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2188-68-3

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Basic Information
CAS No.: 2188-68-3
Name: Lycorine hydrochloride
Molecular Structure:
Molecular Structure of 2188-68-3 (Lycorine hydrochloride)
Formula: C16H17NO4.HCl
Molecular Weight: 323.776
Synonyms: 1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol,2,4,5,7,12b,12c-hexahydro-, hydrochloride, (1S,2S,12bS,12cS)- (9CI);Galanthan-1,2-diol, 3,12-didehydro-9,10-[methylenebis(oxy)]-, hydrochloride, (1a,2b)-;Lycoran-1a,2b-diol, 3,3a-didehydro-, hydrochloride (8CI);Licorin hydrochloride;
Melting Point: 210-212oC
Boiling Point: 477.4 °C at 760 mmHg
Flash Point: 242.5 °C
Appearance: fine crystal powder.
Hazard Symbols:
Risk Codes: 25
Safety: 45
Transport Information: UN 2811 6.1/PG 3
PSA: 62.16000
LogP: 0.68650
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  • Lycorine Hydrochloride

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    2188-68-3

    Lycorine Hydrochloride

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    high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

    Located in Zhengdong New District,?Zhengzhou of Henan province, Henan Allgreen Chemical Co.,Ltd is a comprehensive high-tech modern enterprises integrating professional R&D, pro

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  • Lycorine Hydrochloride

  • Casno:

    2188-68-3

    Lycorine Hydrochloride

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    Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

    Xiamen Aeco Chemical Industrial Co., Ltd(same as Aecochem Corp.) An ISO 9001:2015 Certified Company Your Partner in China, a Professional chemical raw material supplier, our

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  • Lycorine chloride

  • Casno:

    2188-68-3

    Lycorine chloride

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    ADVANTAGE:1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day2. The products are provided with COA, HPLC, NMR, quality assurance, pac

    Chengdu Lemeitian Pharmaceutical Technology Co., Ltd. is a science and technology service enterprise specializing in the basic research of traditional Chinese medicine (botanical m

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Chemistry

Molecular Structure:

Molecular Formula: C16H18ClNO4
Molecular Weight: 323.7714 
Systematic Name: (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol hydrochloride (1:1)
Synonyms of Lycorine hydrochloride (CAS NO.2188-68-3): Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)- ; Licorin hydrochloride ; Lycorine HCl ; Lycoran-1-alpha,2-beta-diol, 3,3-alpha-didehydro-, hydrochloride
CAS NO: 2188-68-3
Classification Code: Peptidyl transferaseCell Signaling and Neuroscience ; Enzyme Inhibitors by Enzyme ; Gene Regulation and Expression ; P to ; RNA-Protein Translation Inhibitors 
Flash Point: 242.5 °C
Enthalpy of Vaporization: 78.09 kJ/mol
Boiling Point: 477.4 °C at 760 mmHg
Vapour Pressure: 6.37E-10 mmHg at 25°C

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 117mg/kg (117mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958.
mouse LD50 intravenous 123mg/kg (123mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: NAUSEA OR VOMITING		 Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958.
mouse LD50 oral 230mg/kg (230mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958.

Safety Profile

Hazard Codes of Lycorine hydrochloride (CAS NO.2188-68-3): ToxicT
Risk Statements: 25 
R25: Toxic if swallowed.
Safety Statements: 45 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 3