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22199-08-2

Basic Information
CAS No.: 22199-08-2
Name: Silver sulfadiazine
Article Data: 7
Molecular Structure:
Molecular Structure of 22199-08-2 (Silver sulfadiazine)
Formula: C10H9AgN4O2S
Molecular Weight: 357.141
Synonyms: Silver,(4-amino-N-2-pyrimidinylbenzenesulfonamidato-NN,O1)-;Sulfanilamide,N1-2-pyrimidinyl-, monosilver(1+) salt (8CI);Benzenesulfonamide,4-amino-N-2-pyrimidinyl-, silver complex;Dermazin;Flamazine;Flammazine;Geben;NSC 625324;Silvadene;Silver 2-sulfanilamidopyrimidine;Silverol;Sulfadiazine silver;
EINECS: 244-834-5
Density: 1.496g/cm3
Melting Point: 285 °C (dec.)(lit.)
Boiling Point: 512.6 °C at 760 mmHg
Flash Point: 263.8 °C
Appearance: solid
Hazard Symbols: IrritantXi
Risk Codes: 36/37/38
Safety: 26-36
PSA: 94.32000
LogP: 3.11490
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    22199-08-2

    Buy Top Purity Silver sulfadiazine

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  • Silversulfadiazine

  • Casno:

    22199-08-2

    Silversulfadiazine

    Min.Order: 1 Milligram

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    GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

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  • Lower Price Sulfadiazine Silver

  • Casno:

    22199-08-2

    Lower Price Sulfadiazine Silver

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    Product name: Sulfadiazine Silver CAS No.: 22199-08-2 Molecule Formula:C10H10AgN4O2S Molecule Weight:358.14 Purity: 99.0% Package: 25kg/drum Description:White to off-white crystalline powder Manufacture Standards:Enterprise Standard

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  • Silver sulfadiazine

  • Casno:

    22199-08-2

    Silver sulfadiazine

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Product Name: Silver sulfadiazine Synonyms: SILVER(I) SULFADIAZINE;silver (4-aminophenyl)sulfonyl-pyrimidin-2-yl-azanide;SILVER SULPHADIAZINE;SILVER SULFADIAZINE;SULPHADIAZINE-AG;SULFADIAZINE SILVER;4-amino-n-(2-pyrimidinyl)benzenesulfonamidesi

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Consensus Reports

Silver and its compounds are on the Community Right-To-Know List. EPA Genetic Toxicology Program.

Standards and Recommendations

OSHA PEL: TWA 0.01 mg(Ag)/m3
ACGIH TLV: TWA 0.01 mg(Ag)/m3

Specification

The Sulfadiazine silver salt is an organic compound with the formula C10H9AgN4O2S. The IUPAC name of this chemical is silver (4-aminophenyl)sulfonyl-pyrimidin-2-ylazanide. With the CAS registry number 22199-08-2, it is also named as Benzenesulfonamide, 4-amino-N-2-pyrimidinyl-, monosilver(1+) salt. The product's categories are Ag (Silver) Compounds;Antibiotics for Research and Experimental Use; Biochemistry; Classes of Metal Compounds; Sulfonamides (Antibiotics for Research and Experimental Use); Transition Metal Compounds; Intermediates & Fine Chemicals; Pharmaceuticals; Sulfur & Selenium Compounds. Besides, it is a topical sulfonamide/silver antibacterial used as a topical burn cream on burns, including chemical burns. It prevents the growth of a wide array of bacteria, as well as yeast, on the damaged skin.

Physical properties about Sulfadiazine silver salt are: (1)ACD/LogP: -0.12; (2)#H bond acceptors: 6; (3)#H bond donors: 3; (4)#Freely Rotating Bonds: 2; (5)Polar Surface Area: 83.57 Å2; (6)Flash Point: 263.8 °C; (7)Enthalpy of Vaporization: 78.38 kJ/mol; (8)Boiling Point: 512.6 °C at 760 mmHg; (9)Vapour Pressure: 1.28E-10 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable protective clothing. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: [Ag+].O=S(=O)([N-]c1ncccn1)c2ccc(N)cc2
(2)InChI: InChI=1/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1
(3)InChIKey: UEJSSZHHYBHCEL-UHFFFAOYAS
(4)Std. InChI: InChI=1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1
(5)Std. InChIKey: UEJSSZHHYBHCEL-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo skin 536mg/kg/21W- (536mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) Lancet. Vol. 340, Pg. 126, 1992.
mouse LDLo intraperitoneal 550mg/kg (550mg/kg)   United States Patent Document. Vol. #4020150,
mouse LDLo oral > 10gm/kg (10000mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 2850, 1980.
mouse LDLo subcutaneous > 10gm/kg (10000mg/kg) LIVER: OTHER CHANGES

BLOOD: CHANGES IN SPLEEN
Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 2850, 1980.
rat LD50 intraperitoneal 126mg/kg (126mg/kg) LIVER: OTHER CHANGES

BLOOD: CHANGES IN SPLEEN

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 2850, 1980.
rat LD50 oral > 10gm/kg (10000mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 637, 1982.
rat LD50 unreported 160mg/kg (160mg/kg)   United States Patent Document. Vol. #4535078,
rat LDLo subcutaneous > 10gm/kg (10000mg/kg) LIVER: OTHER CHANGES

BLOOD: CHANGES IN SPLEEN
Kiso to Rinsho. Clinical Report. Vol. 14, Pg. 2850, 1980.