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| CAS No.: | 23052-81-5 |
|---|---|
| Name: | L-AP4 |
| Article Data: | 12 |
| Molecular Structure: | |
|
|
|
| Formula: | C4H10 N O5 P |
| Molecular Weight: | 183.101 |
| Synonyms: | Butanoicacid, 2-amino-4-phosphono-, (S)-; Butyric acid, 2-amino-4-phosphono-, L- (8CI);(S)-2-Amino-4-phosphonobutanoic acid; L-(+)-2-Amino-4-phosphonobutyric acid;L-2-Amino-4-phosphonobutanoic acid; L-2-Amino-4-phosphonobutyric acid; L-AP 4;L-APB; S-(+)-2-Amino-4-phosphonobutanoic acid |
| EINECS: | 200-258-5 |
| Density: | 1.628g/cm3 |
| Melting Point: | 207-215 ºC |
| Boiling Point: | 491.7°Cat760mmHg |
| Flash Point: | 251.2°C |
| Solubility: | Soluble to 5 mM in water and to 100 mM in 1eq. NaOH |
| Appearance: | white to off-white crystalline powder |
| Hazard Symbols: |
 Xi
|
| Risk Codes: | 36/37/38 |
| Safety: | 26-36 |
| PSA: | 130.66000 |
| LogP: | -0.33360 |
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Chemistry
IUPAC Name: (2S)-2-amino-4-phosphonobutanoic acid
Synonyms: (2S)-2-Amino-4-phosphonobutanoic acid ; Butanoic acid, 2-amino-4-phosphono-, (2S)- ; (S)-2-Amino-4-phosphonobutanoic acid ; (S)-2-Amino-4-phosphono-butyric acid ; 2-Amino-4-phosphonobutanoic acid ; 2-Amino-4-phosphonobutyric acid ; 2-Amino-4-phosphono-butyric acid ; 2-Amino-4-phosphono-butyric acid(S-AP4) ; L-(+)-2-Amino-4-phosphonobutyric acid
CAS NO: 23052-81-5
Molecular Formula of L-AP4 (CAS NO.23052-81-5) : C4H10NO5P
Molecular Weight of L-AP4 (CAS NO.23052-81-5) : 183.1
Molecular Structure of L-AP4 (CAS NO.23052-81-5) : 
Product Categories: Glutamate receptor
Mol File: 23052-81-5.mol
Index of Refraction: 1.545
Surface Tension: 88.8 dyne/cm
Density: 1.628 g/cm3
Flash Point: 251.2 °C
Enthalpy of Vaporization: 83.05 kJ/mol
Boiling Point: 491.7 °C at 760 mmHg
Vapour Pressure: 5.18E-11 mmHg at 25°C
Melting point: 207-215 °C
Storage temp. 0-6°C
Appearance:white to off-white crystalline powder
Uses
L-AP4 (CAS NO.23052-81-5) is a drug used in scientific research, which acts as a group-selective agonist for the group III metabotropic glutamate receptors (mGluR4/6/7/8). It was the first ligand found to act as an agonist selective for this group of mGlu receptors, but does not show selectivity between the different mGluR Group III subtypes. It is widely used in the study of this receptor family and their various functions.
Safety Profile
Hazard Codes 
Xi
Risk Statements 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
WGK Germany 3
Specification
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage: Store in a tightly closed container. Keep refrigerated. (Store below 4°C/39°F.)