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2378-95-2

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Basic Information
CAS No.: 2378-95-2
Name: diethyl N-[4-(methylamino)benzoyl]-L-glutamate
Article Data: 5
Molecular Structure:
Molecular Structure of 2378-95-2 (diethyl N-[4-(methylamino)benzoyl]-L-glutamate)
Formula: C17H24 N2 O5
Molecular Weight: 336.388
Synonyms: Glutamicacid, N-[p-(methylamino)benzoyl]-, diethyl ester (7CI); Glutamic acid,N-[p-(methylamino)benzoyl]-, diethyl ester, L- (8CI); L-Glutamic acid,N-[4-(methylamino)benzoyl]-, diethyl ester (9CI); DiethylN-(p-N-methylaminobenzoyl)glutamate; DiethylN-[4-(methylamino)benzoyl]-L-glutamate; N-(p-Methylaminobenzoyl)glutamic aciddiethyl ester
Density: 1.165g/cm3
Melting Point: 88-89 °C
Boiling Point: 518.3°Cat760mmHg
Flash Point: 267.2°C
PSA: 93.73000
LogP: 2.19700
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Synthetic route
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diethyl N--L-glutamate

2378-95-2

diethyl <4-(N-methylamino)benzoyl>-L-glutamate

Conditions
ConditionsYield
With hydrogenchloride; hydrogen; palladium on activated charcoal In ethanol under 2482.3 Torr; for 3h;80%
13726-52-8

diethyl N-(p-aminobenzoyl)-L-glutamate

74-88-4

methyl iodide

2378-95-2

diethyl <4-(N-methylamino)benzoyl>-L-glutamate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 26h;23%
With N-ethyl-N,N-diisopropylamine In toluene at 90℃; for 18h;
38974-68-4

N-(4-iodo-benzoyl)L-glutamic acid

74-89-5

methylamine

2378-95-2

diethyl <4-(N-methylamino)benzoyl>-L-glutamate

Conditions
ConditionsYield
With sodium hydroxide; copper at 125℃; Behandeln des Dinatrium-Salzes der erhaltenen N-<4-Methylamino-benzoyl>-L-glutaminsaeure mit Chlorwasserstoff enthaltendem Aethanol;
13726-52-8

diethyl N-(p-aminobenzoyl)-L-glutamate

2378-95-2

diethyl <4-(N-methylamino)benzoyl>-L-glutamate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 94 percent / sodium cyanoborohydride, bromocresol green, acetic acid / ethanol / 48 h / Ambient temperature
2: 91 percent / sodium cyanoborohydride, bromocresol green, aq. acetic acid / acetonitrile / 1 h / Ambient temperature
3: 80 percent / hydrogen, HCl / palladium on carbon / ethanol / 3 h / 2482.3 Torr
View Scheme
70280-70-5

diethyl N--L-glutamate

2378-95-2

diethyl <4-(N-methylamino)benzoyl>-L-glutamate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 91 percent / sodium cyanoborohydride, bromocresol green, aq. acetic acid / acetonitrile / 1 h / Ambient temperature
2: 80 percent / hydrogen, HCl / palladium on carbon / ethanol / 3 h / 2482.3 Torr
View Scheme
4271-30-1

N-(4-aminobenzoyl)-L-glutamic acid

2378-95-2

diethyl <4-(N-methylamino)benzoyl>-L-glutamate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium nitrite; aqueous hydrochloric acid; aqueous potassium iodide solution / Diazotization
2: aq. NaOH solution; copper / 125 °C / Behandeln des Dinatrium-Salzes der erhaltenen N-<4-Methylamino-benzoyl>-L-glutaminsaeure mit Chlorwasserstoff enthaltendem Aethanol
View Scheme
13726-52-8, 34136-22-6

diethyl N-(p-aminobenzoyl)-glutamate

584-08-7

potassium carbonate

74-88-4

methyl iodide

2378-95-2

diethyl <4-(N-methylamino)benzoyl>-L-glutamate

Conditions
ConditionsYield
In dichloromethane; ethyl acetate; N,N-dimethyl-formamide
...Expand
2378-95-2

diethyl <4-(N-methylamino)benzoyl>-L-glutamate

106585-53-9

<6-(bromomethyl)-4-oxo-3(4H)-quinazolinyl>methyl 2,2-dimethylpropanoate

106585-59-5

Diethyl N-(4-(N-((3,4-dihydro-4-oxo-3-((pivaloyl)oxy) methyl-6-quinazolinyl)methyl)methylamino)benzoyl)-L-glutamate

Conditions
ConditionsYield
With calcium carbonate In dimethyl amine at 50℃; for 24h;89.3%
624-76-0

Iodoethanol

2378-95-2

diethyl <4-(N-methylamino)benzoyl>-L-glutamate

107716-30-3

diethyl N-<4-benzoyl>-L-glutamate

Conditions
ConditionsYield
In various solvent(s) at 100℃; for 5h;86%
2378-95-2

diethyl <4-(N-methylamino)benzoyl>-L-glutamate

94565-59-0

4-methoxy-6-oxo-7-chloro-5H-pyrimido<4,5-b><1,4>thiazine

94565-72-7

diethyl N-methyl-N-<4-methoxy-6-oxo-5H-pyrimido<4,5-b><1,4>thiazin-7-yl>-p-aminobenzoyl-L-glutamate

Conditions
ConditionsYield
With triethylamine In 1,4-dioxane; water at 18 - 20℃; for 5h;81%
Raw Materials
74-89-5
4271-30-1
74-88-4
38974-68-4
13726-52-8
584-08-7
Downstream Products
59-05-2
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    N-(p-Methylaminobenzoyl)glutamic acid diethyl ester

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  • diethyl N-[4-(methylamino)benzoyl]-L-glutamate

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    2378-95-2

    diethyl N-[4-(methylamino)benzoyl]-L-glutamate

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    2378-95-2

    Diethyl N-(4-Methylamino)-Benzoyl-L-Glutamate

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  • L-Glutamic acid,N-[4-(methylamino)benzoyl]-, 1,5-diethyl ester

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    2378-95-2

    L-Glutamic acid,N-[4-(methylamino)benzoyl]-, 1,5-diethyl ester

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    2378-95-2

    Diethyl N-(4-Methylamino)-Benzoyl-L-Glutamate

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  • 2378-95-2 N-(4-Methylaminobenzoyl)-L-lutamic acid diethylester

  • Casno:

    2378-95-2

    2378-95-2 N-(4-Methylaminobenzoyl)-L-lutamic acid diethylester

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    Specifications CAS No.: 2378-95-2 Other Names: Diethyl N-(4-methylaminobenzoyl)-L-glutamate Place of Origin: Zhejiang, China (Mainland) Type: Pharmaceutical Intermediates Purity: 99.0%min Brand Name: Luyunjia Model Number: 99% Applicat

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  • diethyl N-[4-(methylamino)benzoyl]-L-glutamate

  • Casno:

    2378-95-2

    diethyl N-[4-(methylamino)benzoyl]-L-glutamate

    Min.Order: 0

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    good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg，customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

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     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

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  • L-Glutamic acid,N-[4-(methylamino)benzoyl]-, 1,5-diethyl ester cas 2378-95-2

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    2378-95-2

    L-Glutamic acid,N-[4-(methylamino)benzoyl]-, 1,5-diethyl ester cas 2378-95-2

    Min.Order: 0

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    L-Glutamic acid,N-[4-(methylamino)benzoyl]-, 1,5-diethyl ester cas 2378-95-2Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

    Welcome to Hangzhou Fandachem Co.,Ltd (www.FandaChem.com) Hangzhou Fandachem Co.,Ltd (Fandachem),an experienced and professional China-based Fine Chemical supplier. We supply the

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    China (Mainland)  |  Contact Details

    Business Type:Other

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  • diethyl N-[4-(methylamino)benzoyl]-L-glutamate

  • Casno:

    2378-95-2

    diethyl N-[4-(methylamino)benzoyl]-L-glutamate

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    we produce and sell good chemicals around the world.Appearance:white power Storage:Keep it in dry,shady and cool place Package:as your requirement Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:SEA OR AIR Port:China Main Po

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     China (Mainland)  |  Contact Details

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