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24221-86-1

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Basic Information
CAS No.: 24221-86-1
Name: D-Ephedrine hydrochloride
Article Data: 2
Molecular Structure:
Molecular Structure of 24221-86-1 (D-Ephedrine hydrochloride)
Formula: C10H15 N O . Cl H
Molecular Weight: 201.696
Synonyms: Benzenemethanol,a-[(1R)-1-(methylamino)ethyl]-,hydrochloride, (aS)-(9CI); Benzenemethanol, a-[1-(methylamino)ethyl]-, hydrochloride, [S-(R*,S*)]-; Ephedrine,hydrochloride, (+)- (8CI); (+)-Ephedrine hydrochloride;(1S,2R)-(+)-2-(Methylamino)-1-phenylpropan-1-ol hydrochloride;(1S,2R)-(+)-Ephedrine hydrochloride; (1S,2R)-(+)-Ephedrine hydrochloride;(1S,2R)-(+)-Ephedrinium hydrochloride; (1S,2R)-Ephedrine hydrochloride; CPDD0048; D-(+)-Ephedrine hydrochloride; d-Ephedrine hydrochloride
EINECS: 246-090-7
Density: g/cm3
Melting Point: 218-220 ºC
Boiling Point: 255 °C at 760 mmHg
Flash Point: 85.6 °C
Appearance: White crystalline powder.
Hazard Symbols:
Risk Codes: R22   
Safety: A poison by intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also EPHEDRINE.
PSA: 32.26000
LogP: 2.52080
Raw Materials
90-81-3
Downstream Products
33817-09-3
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Chemistry

Molecular Structure: .
Molecular Formula: C10H15NO.HCl.
Molecular Weight: 201.72.
Melting Point: 218-220 ℃.
Boiling Point: 255 ℃ at 760 mmHg.
Flash Point: 85.6 ℃.

Toxicity Data With Reference

1.   

scu-rat LDLo:160 mg/kg

   JPETAB    Journal of Pharmacology and Experimental Therapeutics. 71 (1941),62.
2.   

orl-mus LD50:785 mg/kg

   JMCMAR    Journal of Medicinal Chemistry. 9 (1966),966.
3.   

ipr-mus LD50:248 mg/kg

   JPETAB    Journal of Pharmacology and Experimental Therapeutics. 158 (1967),135.
4.   

scu-mus LD50:425 mg/kg

   JMCMAR    Journal of Medicinal Chemistry. 9 (1966),966.
5.   

ivn-mus LD50:175 mg/kg

   JMCMAR    Journal of Medicinal Chemistry. 9 (1966),966.
6.   

ivn-rbt LDLo:80 mg/kg

   JPETAB    Journal of Pharmacology and Experimental Therapeutics. 36 (1929),363.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

A poison by intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also EPHEDRINE.