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24390-14-5

Basic Information
CAS No.: 24390-14-5
Name: Doxycycline hyclate
Molecular Structure:
Molecular Structure of 24390-14-5 (Doxycycline hyclate)
Formula: C22H24N2O8.HCl
Molecular Weight: 480.90
Synonyms: Vibramycin (TN);Doxycycline hyclate (USP);(2Z,4S,4aR,5S,5aR,6R,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; ethanol; hydrate; dihydrochloride;Doxycycline hydrochloride hemiethanolate hemihydrate;DOXY;Doryx (TN);Doryx;Doxycycline Hcl;Dipivefrin HCl;
EINECS: 234-198-7
Density:
Melting Point: 206-209?C (dec.)
Boiling Point: 685.2 °C at 760 mmHg
Flash Point: 368.2 °C
Solubility: Soluble in water to 50mg/ml. May require warming.Soluble in water, methanol. Sparingly soluble in ethanol. Insoluble in chloroform and ether.
Appearance: yellow crystallien powder
Hazard Symbols: HarmfulXn
Risk Codes: 22-36/37/38
Safety: 26
Transport Information:
PSA: 392.70000
LogP: 2.24370
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Chemistry

Name: Doxycycline hyclate
Synonyms: Doxycycline hydrochloride hemiethanolate; 2-(Amino-hydroxy-methylidene)-4-dimethylamino-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione hydrochloride hemiethanolate
CAS Registry Number: 24390-14-5
Molecular Formula: C22H24N2O8.HCl
Molecular Weight: 480.90
Molecular Structure:

Uses

DOXYCYCLINE Hyclate may be used to prevent or slow the progression of anthrax after exposure. And DOXYCYCLINE Hyclate may be used in combination with other medicines to treat acne or certain amoeba infections. DOXYCYCLINE Hyclate may also be used to prevent certain types of malaria in travelers who will be visiting malaria-infected areas for less than 4 months.

Consensus Reports

Nick2222 said: Doryx (doxycycline) for Acne: This doesn't allow me to write very much so I can't share my whole story. I hate taking prescription drugs, but I gave Doryx a chance and it's been a God send. I developed acne in my late 20's, after being acne free since puberty. The cyst like acne would hurt badly and leave terrible marks. With Doryx, every zit on my problem areas were completely gone within 4 days and the red marks from past zits have already faded. I was concerned of side effects and I have had none whatsoever. I am supposed to take it everyday, but I only take it Monday-Friday. I once went 5 days without taking it and got a zit, but getting back on the pills cleared it right up. I pay $25 for a months supply, worth every penny.

tonym123 said: doxycycline for Rosacea: Here's the issue, my rosacea abated for the most part while using doxycycline monohydrate 100mg twice daily. The major issue is that I started retaining fluid for no apparent reason (went to doctor, Kidney and endocrinology specialists) and after stopping this drug, the swelling went down remarkably (> 15 lb loss in 4 days). This is a significant problem with other antibiotics also, Levaquin, Ciprofloxacin, etc. Even if a limited number of users have this it is significant. I hope that reading this helps someone else, I suffered for almost 2 years.

Safety Profile

Important safety information:
1)DOXYCYCLINE Hyclate may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to DOXYCYCLINE Hyclate . Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
2)Be sure to use DOXYCYCLINE Hyclate for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
3)DOXYCYCLINE Hyclate only works against bacteria; it does not treat viral infections (eg, the common cold).
4)Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or blood stools occur. Do not treat diarrhea without first checking with your doctor.
5)Long-term or repeated use of DOXYCYCLINE Hyclate may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
6)Do not take more than the recommended dose or take DOXYCYCLINE Hyclate for longer than prescribed without checking with your doctor.
7)Hormonal birth control (eg, birth control pills) may not work as well while you are using DOXYCYCLINE Hyclate . To prevent pregnancy, use an extra form of birth control (eg, condoms).
8)DOXYCYCLINE Hyclate may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking DOXYCYCLINE Hyclate .
9)If you are taking DOXYCYCLINE Hyclate to prevent malaria, please note that no malaria medicine, including DOXYCYCLINE Hyclate , guarantees protection against malaria. Stay in well-screened areas, use mosquito nets, cover the body with clothing, and use insect repellent to avoid being bitten by mosquitoes.
10)Tell your doctor or dentist that you take DOXYCYCLINE Hyclate before you receive any medical or dental care, emergency care, or surgery.
11)Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed while you use DOXYCYCLINE Hyclate . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
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