CAS No.2447-57-6,Sulfadoxine Suppliers,MSDS download

Products Categories

Pharmaceutical (154)
Others (40)
Organic Chemicals (31)
Reagent (6)
Plant Extract (4)
Agrochemicals (3)
Food Additives (2)
(1)
Materials (1)
Basic Inorganic Chemicals (1)

Basic Information

Molecular Structure:
CAS No.:	2447-57-6
Name:	Sulfadoxine

Formula:	C₁₂H₁₄N₄O₄S
Molecular Weight:	310.334
Synonyms:	Benzenesulfonamide,4-amino-N-(5,6-dimethoxy-4-pyrimidinyl)-;4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzensulfonamide;Fanasil;Ro 4-4393;Sulfadoxin;Sulformetoxin;Sulforthodimethoxine;
EINECS:	219-504-9
Density:	1.441 g/cm³
Melting Point:	190-194 °C
Boiling Point:	522.8 °C at 760 mmHg
Flash Point:	270 °C
Solubility:	209.8mg/L(temperature not stated)
Appearance:	White crystalline solid
Hazard Symbols:	Xi
Risk Codes:	36/37/38
Safety:	26
PSA:	124.81000
LogP:	2.61180

Total:185 Page 1 of 5 1 2 3 4 5 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 2447-57-6

Specification

The IUPAC name of 6-(4-Aminobenzenesulfonamido)-4,5-dimethoxypyrimidine is 4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide. With the CAS registry number 2447-57-6, it is also named as Pravadoline; Methanone, (4-methoxyphenyl)(2-methyl-1-(2-(4-morpholinyl)ethyl)-1H-indol-3-yl)-. The product's categories are miscellaneous natural products, intermediates & fine chemicals, pharmaceuticals, antibiotics and bacteriostatic antibiotics. It is white crystalline solid which is toxic and flammable. And it will produce toxic nitrogen oxides and sulfur oxides fumes when buring. So the storage environment should be ventilate, low-temperature and dry.

The other characteristics of this product can be summarized as: (1)ACD/LogP: 0.34; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.33; (4)ACD/LogD (pH 7.4): -0.1; (5)ACD/BCF (pH 5.5): 1.04; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 35.55; (8)ACD/KOC (pH 7.4): 13.23; (9)#H bond acceptors: 8; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 4; (12)Index of Refraction: 1.622; (13)Molar Refractivity: 75.87 cm³; (14)Molar Volume: 215.2 cm³; (15)Polarizability: 30.07×10^-24 cm³; (16)Surface Tension: 69.5 dyne/cm; (17)Enthalpy of Vaporization: 79.63 kJ/mol; (18)Vapour Pressure: 5.01E-11 mmHg at 25°C; (19)Rotatable Bond Count: 5; (20)Tautomer Count: 3; (21)Exact Mass: 310.073576; (22)MonoIsotopic Mass: 310.073576; (23)Topological Polar Surface Area: 125; (24)Heavy Atom Count: 21.

Uses of 6-(4-Aminobenzenesulfonamido)-4,5-dimethoxypyrimidine: It can be used as an antibacterial. And it is an ultra-long-lasting sulfonamide often used in combination with pyrimethamine to treat or prevent malaria. It is usually in combination with other drugs to be used to treat or prevent various infections in livestock. In addition. this chemical can be used in many organic synthesis. For example: 1. It reacts with 5-methyl-indole-2,3-dione to get N-(5,6-dimethoxy-pyrimidin-4-yl)-4-(5-methyl-2-oxo-1,2-dihydro-indol-3-ylideneamino)-benzenesulfonamide. This reaction needs reagent glac. AcOH and solvent ethanol. The yield is 53%.

When you are using this chemical, please be cautious about it as the following. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

People can use the following data to convert to the molecule structure.
1. Smiles: C(=O)(c1c(n(c2ccccc12)CCN1CCOCC1)C)c1ccc(cc1)OC;
2. InChI: InChI=1/C23H26N2O3/c1-17-22(23(26)18-7-9-19(27-2)10-8-18)20-5-3-4-6-21(20)25(17)12-11-24-13-15-28-16-14-24/h3-10H,11-16H2,1-2H3.

The following is the toxicity data which has been tested.

1.	orl-mus LD50:5200 mg/kg	MEIEDD Merck Index. 10 (1983),1276.
2.	ipr-mus LD50:2900 mg/kg	MEIEDD Merck Index. 10 (1983),1276.
3.	scu-mus LD50:2900 mg/kg	MEIEDD Merck Index. 10 (1983),1276.