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247098-18-6

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CAS No.: 247098-18-6
Name: 3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide
Article Data: 7
Molecular Structure:
Molecular Structure of 247098-18-6 (3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide)
Formula: C16H20 N2 O2
Molecular Weight: 272.347
Synonyms: 3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide;3-ETHYL-4-METHYL-2-OXO-PYRROLIDINE-1-[(CARBOXAMIDE)-ETHYL BENZENE)SULPHONYL]-N-ETHYL-CARBAMATE;1-PHENETHYLAMINOCARBONYL-3-ETHYL-4-METHYL-2,5-DIHYDRO-5-PYRROLONE;4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzene
Density: 1.132g/cm3
PSA: 49.41000
LogP: 2.83620
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247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

Conditions
ConditionsYield
In toluene at 120 - 130℃; for 2h; Industrial scale;97%
In n-heptane at 70 - 100℃; for 7h; Temperature;90%
In toluene for 4h; Molecular sieve; Reflux; Inert atmosphere;80%
In toluene Heating;65%
In toluene for 4h; Heating / reflux;

3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamide

622-24-2

2-phenylethyl chloride

247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

Conditions
ConditionsYield
With copper(l) iodide; sodium hydroxide In Petroleum ether at 85℃; for 9h; Temperature;85.24%
With copper(l) iodide; sodium hydroxide In Petroleum ether at 85℃; for 9h; Temperature;85.24%
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1-acetyl-3-ethyl-4-methyl-1,5-dihydro-pyrrol-2-one

247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / Na2CO3; H2O / Heating
2: 65 percent / toluene / Heating
View Scheme
247098-17-5

ethyl-α-ethylacetoacetate cyanohydrin

247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 15 percent / H2; Ac2O / Ra-Ni / 40 °C / 3800 Torr
2: 90 percent / Na2CO3; H2O / Heating
3: 65 percent / toluene / Heating
View Scheme
607-97-6

ethyl 2-ethyl-3-oxobutanoate

247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 80 percent / dimethylformamide / 0 - 5 °C
2: 15 percent / H2; Ac2O / Ra-Ni / 40 °C / 3800 Torr
3: 90 percent / Na2CO3; H2O / Heating
4: 65 percent / toluene / Heating
View Scheme
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

4-{2-[(3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carbonyl)amino]ethyl}benzene-1-sulfonic acid

Conditions
ConditionsYield
With chlorosulfonic acid In tetrahydrofuran at 20℃; Temperature;88.15%
With chlorosulfonic acid In tetrahydrofuran at 20℃; Temperature;88.15%
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

119043-16-2

4-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]benzenesulfonyl chloride

Conditions
ConditionsYield
With chlorosulfonic acid at 10℃;
With chlorosulfonic acid at 15 - 35℃; for 4.5 - 6.5h;
With chlorosulfonic acid In dichloromethane at -5 - 30℃;
With chlorosulfonic acid at 80℃; for 0.5h;
With chlorosulfonic acid In dichloromethane at 30 - 35℃; for 5.5h; Inert atmosphere;
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

119018-29-0

N-{2-[4-(aminosulfonyl)phenyl]ethyl}-3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ClSO3H / 10 °C
2: NH3 / H2O / 4 h / 60 °C
View Scheme
Multi-step reaction with 2 steps
1: chlorosulfonic acid / tetrahydrofuran / 20 °C
2: ammonia / 1,4-dioxane / 35 °C
View Scheme
Multi-step reaction with 2 steps
1: chlorosulfonic acid / dichloromethane / -5 - 30 °C
2: ammonium hydroxide / methanol / 2 h / 20 - 30 °C / Industrial scale
View Scheme
Multi-step reaction with 2 steps
1: chlorosulfonic acid / dichloromethane / 5.5 h / 30 - 35 °C / Inert atmosphere
2: ammonium hydroxide / 16 h / 20 °C
View Scheme
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

trans-hydroxyglimepiride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: ClSO3H / 10 °C
2: NH3 / H2O / 4 h / 60 °C
3: 80 percent / K2CO3 / acetone / 8 h / Heating
4: BF3*OEt2 / CH2Cl2 / 0 °C
View Scheme
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

cis-hydroxyglimepiride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: ClSO3H / 10 °C
2: NH3 / H2O / 4 h / 60 °C
3: 80 percent / K2CO3 / acetone / 8 h / Heating
4: BF3*OEt2 / CH2Cl2 / 0 °C
View Scheme
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  • 3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide

  • Casno:

    247098-18-6

    3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

    Henan Kanbei Chemical Co., Ltd. is a modern high-tech chemical enterprise integrating R&D, production and sales. The company has strong technical strength, advanced equipment, stri

  •  Henan Kanbei Chemical Co.,LTD

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-152-37804566

    Address:Evergrande Future City, intersection of Zhengkai Avenue and Sixteenth Street, Kaifeng Area, Henan Pilot Free Trade Zone

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  • 4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

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    247098-18-6

    4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

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    Hangzhou ZeErRui Chemical Co., Ltd. is focused on customization, research and development and production of APIs and advanced intermediates, which can effectively compensate for the deficiencies of traditional CRO and CMO. Priority of high-tech barri

    Hangzhou ZeErRui Chemical Co., Ltd. located in Lingang industrial areas, our plant covers an area of 6000 square meters.ZeErRui dedicated to the development, production and marketi

  •  Hangzhou ZeErRui Chemical Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-82512721

    Address:No 317,Jingling Road,Guali Town,Xiaoshan District

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  • 4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

  • Casno:

    247098-18-6

    4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Wuhan Xinweiye Chemical Co., Ltd. is mainly engaged in the process development and production of customized synthesis and pharmaceutical intermediates. We have professional researchers in organic synthesis, analytical chemistry and production process

    Wuhan NewGreat Chemical Co., Ltd. is located in Wuhan Donghu High-tech Development Zone. Wuhan has unique geographical advantages. It is close to Zhengzhou, Changsha, Nanchang and

  •  Wuhan Newgreat Chemical Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-027-85953558

    Address:East Lake high tech Development Zone, Wuhan, 262, No.

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  • 3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide

  • Casno:

    247098-18-6

    3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta

    Hebei Quanhe Biotechnology Co. LTD. is an enterprise specializing in the research and development, production and trade of pharmaceutical intermediates, apis and chemical raw mater

  •  Hebei Quanhe Biotechnology Co. LTD

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-0319-5919066

    Address:Haida Business Center, Xiangdu District

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  • 4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

  • Casno:

    247098-18-6

    4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamideAppearance:Powder and crystal Storage:Keep in cool, dry and ventilated place Package:foil bags, drums or bottles as customers' requirements Application:Intermediates Transportation:By e

    Hunan Runhui Chem Co., Ltd. is a comprehensive Fine chemicals and Pharmaceuticals Intermediates supplier in China , Established in Changsha City of Hunan province registered capit

  •  Hunan Longxianng Runhui Trading Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-731-85570686

    Address:29 Floor,Changsheng Upper Strata,Furong District,China

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  • 4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

  • Casno:

    247098-18-6

    4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    factory?direct?sale Application:Fine chemical intermediates, used as the main raw material for the synthesis of various pesticides, medicines, surfactants, polymer monomers, and antifungal agents

    We are a team of industry experts, dedicated to delivering the best chemical solutions from quality suppliers across China. Putting our customers first, we take a holistic approach

  •  Chemlyte Solutions

    China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+86-189 8945 5137

    Address:Jian Qiao Community, 789 Shenhua Road, Xihu District, Hangzhou, China, 310000

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