CAS No.25611-78-3,1,2-Diphenylethylamine Suppliers,MSDS download

Products Categories

Pharmaceutical (24)
Organic Chemicals (9)
Others (4)
Basic Inorganic Chemicals (2)

Basic Information

Molecular Structure:
CAS No.:	25611-78-3
Name:	1,2-Diphenylethylamine
Article Data:	56

Formula:	C₁₄H₁₅N
Molecular Weight:	197.28
Synonyms:	Ethylamine,1,2-diphenyl- (6CI,7CI);(?à)-1,2-Diphenylethylamine;(?à)-a,b-Diphenylethylamine;(?à)-a-Phenylphenethylamine;1,2-Diphenethylamine;1,2-Diphenylethanamine;1,2-Diphenylethylamine;1-Amino-1,2-diphenylethane;DL-1,2-Diphenylethylamine;Ethanamine, 1,2-diphenyl-;dl-a-Benzylbenzylamine;a-Benzylbenzylamine;a-Phenylbenzeneethanamine;
EINECS:	247-126-4
Density:	1.02 g/mL at 25 °C(lit.)
Boiling Point:	311.1 °C at 760 mmHg
Flash Point:	136.8 °C
Appearance:	COLORLESS TO YELLOW LIQUID
Hazard Symbols:	Xi
Risk Codes:	36/37/38
Safety:	26-37/39
PSA:	26.02000
LogP:	3.62940

Synthetic route

: 695231-57-3
(1,2-diphenyl-ethyl)-carbamic acid tert-butyl ester

: 25611-78-3
(R,S)-1,2-diphenylethylamine

Conditions

Conditions	Yield
With water; sodium t-butanolate In tetrahydrofuran Heating;	100%

: 103-30-0
(E)-1,2-diphenyl-ethene

: 25611-78-3
(R,S)-1,2-diphenylethylamine

Conditions

Conditions	Yield
With 10-phenyl-9-(2,4,6-trimethylphenyl)acridinium tetrafluoroborate; ammonium carbonate; 2-amino-benzenethiol In dichloromethane; chlorobenzene at 20℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube; Irradiation;	98%
Multi-step reaction with 2 steps 1: PrPPTNO / acetonitrile / 16 h / 30 °C / Irradiation 2: hydrogen; palladium on activated charcoal / ethyl acetate / 3 h / 50 °C View Scheme

: 451-40-1
phenyl benzyl ketone

: 25611-78-3
(R,S)-1,2-diphenylethylamine

Conditions

Conditions	Yield
With ammonia; hydrogen In water at 130℃; for 24h; Autoclave;	93%
With ammonium formate; C25H29ClIrN2O3P at 50℃; for 18h; Leukardt-Wallach Amination; Sealed tube;	69%
With formic acid; ammonium carbonate
Stage #1: phenyl benzyl ketone With ammonium formate at 160℃; Stage #2: With hydrogenchloride In methanol
Multi-step reaction with 2 steps 1: hydroxylamine hydrochloride; sodium acetate / ethanol / 6 h / 60 °C 2: hydrogenchloride; palladium 10% on activated carbon; hydrogen / ethanol; water View Scheme

: 645-49-8
cis-stilben

: 25611-78-3
(R,S)-1,2-diphenylethylamine

Conditions

Conditions	Yield
With 10-phenyl-9-(2,4,6-trimethylphenyl)acridinium tetrafluoroborate; ammonium carbonate; 2-amino-benzenethiol In dichloromethane; chlorobenzene at 20℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube; Irradiation;	93%

: 100-52-7
benzaldehyde

: 108-88-3
toluene

: 25611-78-3
(R,S)-1,2-diphenylethylamine

Conditions

Conditions	Yield
With sodium hexamethyldisilazane; caesium carbonate at 110℃; for 12h; Catalytic behavior; Reagent/catalyst; Sealed tube; Inert atmosphere; chemoselective reaction;	90%

: 588-59-0
stilbene

: 25611-78-3
(R,S)-1,2-diphenylethylamine

Conditions

Conditions	Yield
With terephthalonitrile; ammonia In water; acetonitrile; benzene for 31h; Ambient temperature; Irradiation;	88%
With terephthalonitrile; ammonia In water; acetonitrile for 20h; Mechanism; Ambient temperature; Irradiation; other solvent; regiochemistry on photoamination of other 1,2-diarylethene via electron transfer;	46%

: N-(1,2-diphenylethyl)-2-(4-methoxyphenyl)propan-2-amine

: 25611-78-3
(R,S)-1,2-diphenylethylamine

Conditions

Conditions	Yield
With trifluoroacetic acid at 50℃; for 12.5h;	88%

: 33542-84-6
N-(1,2-diphenyl-ethyl)-N-benzylamine

: 25611-78-3
(R,S)-1,2-diphenylethylamine

Conditions

Conditions	Yield
With palladium on activated charcoal; hydrogen In ethyl acetate at 50℃; for 3h;	84%

: 1086209-16-6
α-benzylideneamino-α-phenylacetamide

: 100-39-0
benzyl bromide

A: 7505-92-2
2-oxo-2-phenylacetamide

B: 25611-78-3
(R,S)-1,2-diphenylethylamine

C: 145143-11-9
2-Amino-2,3-diphenyl-propionamide

Conditions

Conditions	Yield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In dichloromethane Ambient temperature; phase-transfer conditions; Yields of byproduct given;	A n/a B n/a C 79%

...Expand

: 1589-82-8
phenylmagnesium bromide

: 100-47-0
benzonitrile

: 25611-78-3
(R,S)-1,2-diphenylethylamine

Conditions

Conditions	Yield
Stage #1: phenylmagnesium bromide; benzonitrile In tetrahydrofuran; diethyl ether at 100℃; for 0.166667h; Microwave irradiation; Stage #2: With sodium tetrahydroborate In tetrahydrofuran; methanol; diethyl ether for 0.0833333h;	76%

Country:
- China (Mainland)(37)
- United States(2)
Business Type:
All

Lab/Research institutions

Trading Company

Manufacturers

Other
Certificate:
Manufacturer

Enterprise Authentication

ISO

GMP

FDA

HALAL

Display:default sort
Suppiers of more reward points first

New supplier

Total:36 Page 1 of 1 1

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 25611-78-3

Specification

This chemical is called 1,2-Diphenylethylamine, and it can also be named as Benzeneethanamine, α-phenyl-. With the molecular formula of C₁₄H₁₅N, its molecular weight is 197.28. The CAS registry number of this chemical is 25611-78-3, and its product categories are Amines; C11 to C38; Nitrogen Compounds.

Other characteristics of the 1,2-Diphenylethylamine can be summarised as followings: (1)ACD/LogP: 3.13; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.07; (4)ACD/LogD (pH 7.4): 0.96; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1.04; (8)ACD/KOC (pH 7.4): 8.13; (9)#H bond acceptors: 1; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 3.24 Å²; (13)Index of Refraction: 1.596; (14)Molar Refractivity: 63.82 cm³; (15)Molar Volume: 187.3 cm³; (16)Polarizability: 25.3×10^-24cm³; (17)Surface Tension: 44.4 dyne/cm; (18)Density: 1.02 g/cm³; (19)Flash Point: 136.8 °C; (20)Enthalpy of Vaporization: 55.2 kJ/mol; (21)Boiling Point: 311.1 °C at 760 mmHg; (22)Vapour Pressure: 0.000575 mmHg at 25°C.

Uses of this chemical: The N-bibenzyl-a-yl-benzamide could be obtained by the reactants of benzoyl chloride and 1,2-Diphenylethylamine, the reagent of 15percent sodium hydroxide and the solvent of H₂O. This reaction should be taken for 1 hour at the temperature of 0 °C, and its yield is 98 %.

When you are using this chemical, please be cautious about it as the following: This chemical is irritating to eyes, respiratory system and skin, so you should wear suitable protective clothing when you use it. In case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
1.SMILES: NC(c1ccccc1)Cc2ccccc2
2.InChI: InChI=1/C14H15N/c15-14(13-9-5-2-6-10-13)11-12-7-3-1-4-8-12/h1-10,14H,11,15H2
3.InChIKey: DTGGNTMERRTPLR-UHFFFAOYAN
4.Std. InChI: InChI=1S/C14H15N/c15-14(13-9-5-2-6-10-13)11-12-7-3-1-4-8-12/h1-10,14H,11,15H2
5.Std. InChIKey: DTGGNTMERRTPLR-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	145mg/kg (145mg/kg)	BEHAVIORAL: FOOD INTAKE (ANIMAL) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 1561, 1978. Link to PubMed
rat	LDLo	intraperitoneal	100mg/kg (100mg/kg)		Pharmaceutical Bulletin. Vol. 1, Pg. 174, 1953.