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CAS No.: | 2616-64-0 |
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Name: | (2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic |
Article Data: | 26 |
Molecular Structure: | |
Formula: | C15H22 N2 O18 P2 |
Molecular Weight: | 580.29 |
Synonyms: | Glucopyranuronicacid, 1-ester with uridine 5'-pyrophosphate (7CI); Glucopyranuronic acid, 1®5'-ester with uridine5'-(trihydrogen pyrophosphate), a-D- (8CI); a-D-Glucopyranuronicacid, ester with uridine 5'-pyrophosphate (6CI); UDP-D-glucuronic acid;UDP-GlcUA; UDP-glucuronic acid; UDP-a-D-glucuronic acid; Uridine 5'-diphospho-a-D-glucuronic acid; Uridine5'-diphosphoglucuronic acid; Uridine diphosphate glucuronic acid; Uridinediphospho-D-glucuronic acid; Uridine diphosphoglucuronic acid; Uridinepyrophosphoglucuronic acid |
Density: | 2.05g/cm3 |
Boiling Point: | °Cat760mmHg |
Flash Point: | °C |
PSA: | 333.68000 |
LogP: | -4.70140 |
Conditions | Yield |
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With histidine-6-nicotinamide adenine dinucleotide hydride oxidase; histidine-6-uridine 5’-diphosphate-α-D-glucose-dehydrogenase; sucrose synthase 1; NAD In aq. buffer at 30℃; for 5h; pH=7.8; Enzymatic reaction; | 100% |
Multi-step reaction with 2 steps 1: sucrose synthase 1 / Enzymatic reaction 2: NAD; histidine-6-uridine 5’-diphosphate-α-D-glucose-dehydrogenase; histidine-6-nicotinamide adenine dinucleotide hydride oxidase / aq. buffer / 5 h / 30 °C / pH 8.7 / Enzymatic reaction View Scheme |
Conditions | Yield |
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With glucuronokinase from Arabidopsis thaliana; pyrophosphatase from E. coli; UDP-sugar pyrophosphorylasegene from Arabidopsis thaliana; ATP; magnesium chloride In aq. buffer at 37℃; pH=8; Enzymatic reaction; | 89% |
Conditions | Yield |
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With Tris buffer; NAD; 2-oxo-propionic acid for 12h; lactate dehydrogenase, uridine 5'-diphosphoglucose dehydrogenase (UDP-Glc dehydrogenase); | 87% |
With UDP-glucose dehydrogenase; NAD; 2-oxo-propionic acid for 24h; Ambient temperature; pH 7.5 - 8.2; | 68% |
at 25℃; potassium bicinate buffer (pH 8.5), NAD(+), UDP-glucose dehydrogenase; kinetic parameters: Km, Vm; |
Conditions | Yield |
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With recombinant Arabidopsis thaliana glucuronokinase; molecular weight around 42 kDa; recombinant Bifidobacterium longum UDP-sugar pyrophosphorylase; recombinant Pasteurella multocida inorganic pyrophosphatase; ATP; magnesium chloride In aq. buffer at 37℃; for 36h; pH=6.5; Catalytic behavior; Reagent/catalyst; pH-value; Enzymatic reaction; chemoselective reaction; | 80% |
With glucuronokinase from Arabidopsis thaliana; inorganic pyrophosphatase from P. multocida; UDP-sugar pyrophosphorylase from Arabidopsis thaliana; ATP; sodium hydroxide; magnesium chloride In aq. buffer at 37℃; for 24h; pH=7.5; Enzymatic reaction; |
O5'-(amino-hydroxy-phosphoryl)-uridine
α-D-glucopyranuronic acid 1-phosphate
UDP-glucuronic acid
uridine diphospho-α-D-gluco-hexodialdose
UDP-glucuronic acid
Conditions | Yield |
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With Streptococcus pyogenes UDP-glucose dehydrogenase; nicotinamide adenine dinucleotide Yield given; | |
With Streptococcus pyogenes UDP-glucose dehydrogenase; nicotinamide adenine dinucleotide Rate constant; Michaelis constant; |
UDP-glucuronic acid
Conditions | Yield |
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enzymatische Synthese mit Hilfe von UDPglucose-dehydrogenase aus Leber-Homogenaten; | |
enzymatische Synthese mit Hilfe von UDPglucose-dehydrogenase aus Knorpel-Homogenaten; | |
enzymatische Synthese mit Hilfe von UDPglucose-dehydrogenase aus Erbsen-Saemlingen; | |
enzymatische Synthese mit Hilfe von UDPglucose-dehydrogenase aus Extrakten von Pneumococcus-Staemmen; |
α-D-glucopyranuronic acid 1-phosphate
UDP-glucuronic acid
Conditions | Yield |
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reversible enzymatische Bildung mit Hilfe eines Enzym-Praeparats aus Phaseolus aureus; |
Acetic acid (2S,3R,4S,5S,6S)-2,3,5-triacetoxy-6-formyl-tetrahydro-pyran-4-yl ester
UDP-glucuronic acid
Conditions | Yield |
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Multi-step reaction with 6 steps 1: Zn, TiCl4 2: H3PO4 / 50 °C 3: NaOMe / methanol 4: 1.) O3, 2.) Me2S / 1.) -78 deg C, 2.) -20 deg C, 12 h 5: UDP-glucose pyrophosphorylase, pyrophosphotase 6: Streptococcus pyogenes UDP-glucose dehydrogenase, NAD(+) / Michaelis constant View Scheme |
Conditions | Yield |
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Multi-step reaction with 2 steps 1: UDP-glucose pyrophosphorylase, pyrophosphotase 2: Streptococcus pyogenes UDP-glucose dehydrogenase, NAD(+) / Michaelis constant View Scheme | |
Multi-step reaction with 2 steps 1: Bacillus cerius UDP-Glc phosphorylase / Enzymatic reaction 2: recombinant Bacillus cerius UDP-glucose 6-dehydrogenase; nicotinamide adenine dinucleotide / 0.25 h / 37 °C / pH 8 / aq. phosphate buffer; Enzymatic reaction View Scheme | |
Multi-step reaction with 2 steps 1: bovine serum albumin; magnesium chloride; S. cerevisiae hexokinase; rabbit muscle phosphoglucomutase; UTP-glucose-1-phosphate uridylyltransferase from Bifidobacterium longum subsp. longum JCM 1217; S. cerevisiae inorganic pyrophosphatase; 6-phospho-α-D-glucopyranosyl-1-phosphate / aq. buffer / 24 h / 30 °C / pH 7.5 / Enzymatic reaction 2: 9,10-phenanthrenequinone; Candida tenuis xylose reductase; nicotinamide adenine dinucleotide; human UDP-glucose dehydrogenase; dihydrogen peroxide / aq. buffer / 3 h / 37 °C / pH 7.5 / Enzymatic reaction View Scheme |