CAS No.2682-49-7,1,3-THIAZOLIDIN-2-ONE Suppliers

Products Categories

Pharmaceutical (73)
Organic Chemicals (22)
Agrochemicals (10)
Others (7)
Materials (5)
Reagent (2)
Catalyst and Auxiliary (1)
Plant Extract (1)

Basic Information

Molecular Structure:
CAS No.:	2682-49-7
Name:	1,3-THIAZOLIDIN-2-ONE
Article Data:	27

Formula:	C₃H₅NOS
Molecular Weight:	103.145
Synonyms:	2-Oxothiazolidine;NSC 122613;Thiazolidin-2-one;Thiazolidone;2-Thiazolidinone HOMT;1,3-Thiazolan-2-one;
EINECS:	1312995-182-4
Density:	1.278 g/cm³
Melting Point:	53-54 °C
Boiling Point:	247.6 °C at 760 mmHg
Flash Point:	103.5 °C
PSA:	54.40000
LogP:	0.77160

Synthetic route

: 201230-82-2
carbon monoxide

: 60-23-1
Cysteamine

: 2682-49-7
thiazolidine-2-one

Conditions

Conditions	Yield
With selenium; oxygen; acetonitrile	98%
Stage #1: carbon monoxide; Cysteamine With potassium carbonate; sulfur In N,N-dimethyl-formamide at 20℃; under 760 Torr; for 4h; Stage #2: With oxygen In N,N-dimethyl-formamide at 20℃; under 760 Torr; for 2h;	87%

: 156-57-0
2-mercaptoethylamine hydrochloride

: 57-13-6
urea

: 2682-49-7
thiazolidine-2-one

Conditions

Conditions	Yield
at 180℃; for 3h; Temperature; Time; Concentration;	85%

: 463-58-1
carbon oxide sulfide

: 2576-47-8
2-bromoethylamine hydrobromide

: 2682-49-7
thiazolidine-2-one

Conditions

Conditions	Yield
With potassium hydroxide In methanol at 20℃; for 1h;	80%

: 3582-05-6
trifluoromethyl trifluoromethanesulfonate

: 60-23-1
Cysteamine

: 2682-49-7
thiazolidine-2-one

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 1h; Sealed tube;	78%

: 156-57-0
2-mercaptoethylamine hydrochloride

: 530-62-1
1,1'-carbonyldiimidazole

: 2682-49-7
thiazolidine-2-one

Conditions

Conditions	Yield
Stage #1: 2-mercaptoethylamine hydrochloride; 1,1'-carbonyldiimidazole With 18-crown-6 ether; potassium carbonate In acetonitrile for 18h; Heating; Stage #2: With water In acetonitrile for 4h; Heating; Further stages.;	68%
In ethanol for 15h; Ambient temperature;	63%
Stage #1: 2-mercaptoethylamine hydrochloride; 1,1'-carbonyldiimidazole With potassium carbonate; 18-crown-6 ether In acetonitrile at 80℃; for 19h; Heating / reflux; Stage #2: With sodium carbonate In water for 1h; Heating / reflux;	42%

: 134469-06-0
thiazolidine-2-thione

: 2682-49-7
thiazolidine-2-one

Conditions

Conditions	Yield
With sodium; 2-bromoethanol In ethanol for 4h; Inert atmosphere; Reflux;	56%
With sodium ethanolate; 2-bromoethanol In ethanol at 60℃; for 4h;

: 134469-06-0
thiazolidine-2-thione

: 540-51-2
2-bromoethanol

: 2682-49-7
thiazolidine-2-one

Conditions

Conditions	Yield
With sodium ethanolate In ethanol for 4h; Inert atmosphere; Reflux;	56%

: 88512-18-9
(2-mercapto-ethyl)-carbamic acid ethyl ester

: 2682-49-7
thiazolidine-2-one

Conditions

Conditions	Yield
With hydrotalcite; magnesium aluminum In toluene for 5h; Heating;	50%

: dithiocarbonic acid S-(2-amino-ethyl ester)-S'-methyl ester; hydrochloride

: 2682-49-7
thiazolidine-2-one

Conditions

Conditions	Yield
With sodium hydroxide

: 113511-38-9
S-(2-aminoethyl)-S’-benzyldithiocarbonate hydrochloride

: 2682-49-7
thiazolidine-2-one

Conditions

Conditions	Yield
With sodium hydroxide

Country:
Business Type:
All

Lab/Research institutions

Trading Company

Manufacturers

Other
Certificate:
Manufacturer

Enterprise Authentication

ISO

GMP

FDA

HALAL

Display:default sort
Suppiers of more reward points first

New supplier

Total:97 Page 1 of 3 1 2 3 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 2682-49-7

Specification

The 1,3-Thiazolan-2-one, with the CAS registry number 2682-49-7, is also known as Thiazolidin-2-one. It belongs to the product categories of API intermediates; Agricultural chemical; Plant growth modifier; Fosthiazate;fungicide; Pesticide. This chemical's molecular formula is C₃H₅NOS and molecular weight is 103.14. What's more, its systematic name is 1,3-Thiazolidin-2-one.

Physical properties of 1,3-Thiazolan-2-one are: (1)ACD/LogP: 0.427; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.43; (4)ACD/LogD (pH 7.4): 0.43; (5)ACD/BCF (pH 5.5): 1.24; (6)ACD/BCF (pH 7.4): 1.24; (7)ACD/KOC (pH 5.5): 40.68; (8)ACD/KOC (pH 7.4): 40.68; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 54.4 Å²; (13)Index of Refraction: 1.544; (14)Molar Refractivity: 25.476 cm³; (15)Molar Volume: 80.725 cm³; (16)Polarizability: 10.099×10^-24cm³; (17)Surface Tension: 42.7 dyne/cm; (18)Density: 1.278 g/cm³; (19)Flash Point: 103.5 °C; (20)Enthalpy of Vaporization: 56.32 kJ/mol; (21)Boiling Point: 247.6 °C at 760 mmHg; (22)Vapour Pressure: 0.004 mmHg at 25°C.

Preparation: this chemical can be prepared by carbon oxide sulfide and 2-bromo-ethylamine; hydrobromide at the temperature of 20 °C. This reaction will need reagent KOH and solvent methanol with the reaction time of 1 hour. The yield is about 80%.

1,3-Thiazolan-2-one can be prepared by carbon oxide sulfide and 2-bromo-ethylamine; hydrobromide at the temperature of 20 °C

Uses of 1,3-Thiazolan-2-one: it can be used to produce 3-(3-methyl-5-nitro-3H-imidazol-4-yl)-thiazolidin-2-one at the temperature of 15 - 100 °C. It will need reagent NaH and solvent dimethylformamide with the reaction time of 135 min. The yield is about 83%.

1,3-Thiazolan-2-one can be used to produce 3-(3-methyl-5-nitro-3H-imidazol-4-yl)-thiazolidin-2-one at the temperature of 15 - 100 °C

You can still convert the following datas into molecular structure:
(1)SMILES: O=C1SCCN
(2)Std. InChI: InChI=1S/C3H5NOS/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)
(3)Std. InChIKey: SLYRGJDSFOCAAI-UHFFFAOYSA-N