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CAS No.: | 2706-56-1 |
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Name: | 2-Pyridylethylamine |
Article Data: | 25 |
Molecular Structure: | |
Formula: | C7H10N2 |
Molecular Weight: | 122.17 |
Synonyms: | Pyridine,2-(2-aminoethyl)- (6CI,7CI,8CI);2-(2-Aminoethyl)pyridine;2-(2-Pyridinyl)ethanamine;2-(2-Pyridinyl)ethylamine;2-(2-Pyridyl)ethylamine;2-(2'-Aminoethyl)pyridine;2-(2'-Pyridyl)ethylamine;2-(a-Pyridyl)ethylamine;2-(b-Aminoethyl)pyridine;2-Aminoethylpyridine;2'-Aminoethyl-2-pyridine;Demethylbetahistine;N-[2-(2-Pyridinyl)ethyl]amine;NSC 71989;a-(2-Aminoethyl)pyridine;a-Pyridylethylamine; |
EINECS: | 220-295-1 |
Density: | 1.025 g/cm3 |
Melting Point: | 198-200 °C(Solv: ethanol (64-17-5)) |
Boiling Point: | 207.9 °C at 760 mmHg |
Flash Point: | 100.6 °C |
Solubility: | Soluble in water (partly), and most common polar solvent. Insoluble in non-polar solvents, and oils. |
Appearance: | clear colorless to yellow liquid |
Hazard Symbols: | Xi |
Risk Codes: | 36/37/38-34 |
Safety: | 26-36-45-36/37/39 |
Transport Information: | UN 2735 |
PSA: | 38.91000 |
LogP: | 1.28310 |
2-(aminoethyl)pyridine
Conditions | Yield |
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With palladium on activated charcoal; hydrogen In 1,4-dioxane; ethanol at 20℃; for 4h; | 91% |
Conditions | Yield |
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A 56% B n/a |
Conditions | Yield |
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With ammonium chloride In methanol; water for 8h; Heating; | A 30% B 50% |
With ammonium chloride In methanol Heating; |
Conditions | Yield |
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With ammonium chloride In methanol; water for 16h; Reflux; | 29% |
With ammonium chloride |
2-(2-chloroethyl)pyridine
2-(aminoethyl)pyridine
Conditions | Yield |
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With ethanol; ammonia at 100℃; | |
Multi-step reaction with 2 steps 1: sodium azide / N,N-dimethyl-formamide / 12 h / 70 °C 2: palladium on activated charcoal; hydrogen / ethanol; 1,4-dioxane / 4 h / 20 °C View Scheme |
2-amino-1-[2]pyridyl-ethanone
2-(aminoethyl)pyridine
Conditions | Yield |
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With hydrogenchloride; platinum Hydrogenation; |
α-(aminomethyl)-2-pyridinemethanol
2-(aminoethyl)pyridine
Conditions | Yield |
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With hydrogenchloride; platinum Hydrogenation; |
(2-[2]pyridyl-ethyl)-carbamic acid methyl ester
2-(aminoethyl)pyridine
Conditions | Yield |
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With hydrogenchloride |
Diphenyl-(2-pyridin-2-yl-ethylamino)-methanol
A
2-(aminoethyl)pyridine
B
benzophenone
Conditions | Yield |
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With water In acetonitrile at 30℃; Rate constant; |
2-Pyridylethylamine, with the CAS Registry Number 2706-56-1, has the Synonyms of 2-Aminoethylpyridine; 2-Pyridineethanamine; 2-(2-Aminoethyl)pyridine; 2-(2-Pyridyl)ethylamine. The Molecular Formula is C7H10N2 and Molecular Weight is122.17. It Appearances in yellowish clear liquid. 2-Pyridylethylamine is a histamine agonist which is selective for the H1 subtype. 2-Pyridylethylamine can be used as pharmaceutical intermediate.
Physical properties about 2-Pyridylethylamine are: (1)ACD/LogP: -0.11; (2)ACD/LogD (pH 5.5): -3.09; (3)ACD/LogD (pH 7.4): -1.77; (4)ACD/BCF (pH 5.5): 1.00; (5)ACD/BCF (pH 7.4): 1.00; (6)ACD/KOC (pH 5.5): 1.00; (7)ACD/KOC (pH 7.4): 1.00; (8)#H bond acceptors: 2; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 3; (11)Index of Refraction: 1.541; (12)Molar Refractivity: 37.429 cm3; (13)Molar Volume: 119.152 cm3; (14)Polarizability: 14.838 10-24cm3; (15)Surface Tension: 44.101001739502 dyne/cm; (16)Density: 1.025 g/cm3; (17)Flash Point: 100.556 °C; (18)Enthalpy of Vaporization: 44.418 kJ/mol; (19)Boiling Point: 207.923 °C at 760 mmHg; (20)Vapour Pressure: 0.219999998807907 mmHg at 25°C
When you are using this chemical, please be cautious about it as the following:
1. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice;
2. Wear suitable protective clothing;
3. In case of accident or if you feel unwell, seek medical advice immediately (show label where possible);
4. Wear suitable protective clothing, gloves and eye/face protection;
You can still convert the following datas into molecular structure:
(1)InChI=1S/C7H10N2/c8-5-4-7-3-1-2-6-9-7/h1-3,6H,4-5,8H2;
(2)InChIKey=XPQIPUZPSLAZDV-UHFFFAOYSA-N;
(3)Smilesn1c(cccc1)CCN