CAS No.28300-74-5,Potassium antimonyl tartrate sesquihydrate Suppliers,MSDS download

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Basic Information

Molecular Structure:
CAS No.:	28300-74-5
Name:	Potassium antimonyl tartrate sesquihydrate

Formula:	C₈H₄K₂O₁₂Sb₂^.3(H₂O)
Molecular Weight:	667.87
Synonyms:	Antimonate(2-),bis[m-[2,3-di(hydroxy-kO)butanedioato(4-)-kO1:kO4]]di-, dipotassium, trihydrate, stereoisomer (9CI);Antimonate(2-), bis[m-tartrato(4-)]di-, dipotassium, trihydrate (8CI);Antimonate(1-),aqua[tartrato(4-)]-, potassium, sesquihydrate, dimer;Antimony potassium tartrate;Antimonyl potassium tartrate, sesquihydrate;Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, antimony potassium salt;Potassium antimony tartrate;Tartaremetic;Tartox;
EINECS:	234-293-3
Density:	2.607 g/cm³
Melting Point:	≥300 °C(lit.)
Solubility:	water: 8.3 g/100 mL
Appearance:	colourless crystals
Hazard Symbols:	Xn,N
Risk Codes:	20/22-51/53
Safety:	61
Transport Information:	UN 1551 6.1/PG 3
PSA:	151.35000
LogP:	-2.66350

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Chemistry

Empirical Formula: C₈H₁₀K₂O₁₅Sb₂
Molecular Weight: 667.8726 g/mol
Melting point: ≥300 °C(lit.)
Water solubility: 8.3 g/100 mL
Appearance: Colourless crystals
Structure of Potassium antimonyl tartrate sesquihydrate (CAS NO.28300-74-5):

Product Category of Potassium antimonyl tartrate sesquihydrate (CAS NO.28300-74-5): Industrial/Fine Chemicals;Organometallics

Uses

Potassium antimonyl tartrate sesquihydrate (CAS NO.28300-74-5) can be used for anti-blood-sucking insects drugs added to animal feed.

Production

The product can be derived from tartaric acid by via antimonide. Take the mixture of four copies of Antimony trioxide , and 5 copies of Potassium hydrogen tartrate into 40 copies of hot water. While stirring while heating, so that the most dissolved and still hot filtration, and then cooling and crystallization. Filtration and then refined for re-crystallization.

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	intraperitoneal	15mg/kg (15mg/kg)		Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
guinea pig	LDLo	intramuscular	55mg/kg (55mg/kg)		Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
human	LDLo	oral	2mg/kg (2mg/kg)		Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 1097, 1966.
human	TDLo	intravenous	1392ug/kg (1.392mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Lancet. Vol. 210, Pg. 227, 1926.
man	LD50	intravenous	249mg/kg/9D-I (249mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" GASTROINTESTINAL: NAUSEA OR VOMITING	Journal of Tropical Medicine and Hygiene. Vol. 21, Pg. 38, 1918.
man	LDLo	intravenous	12mg/kg/1W-I (12mg/kg)	LIVER: OTHER CHANGES KIDNEY, URETER, AND BLADDER: OTHER CHANGES	Lancet. Vol. 210, Pg. 227, 1926.
mouse	LD50	intraperitoneal	33mg/kg (33mg/kg)		Bulletin of the World Health Organization. Vol. 53, Pg. 379, 1976.
mouse	LD50	intravenous	45mg/kg (45mg/kg)		Fortschritte der Arzneimittelforschung. Progress in Drug Research. Vol. 17, Pg. 108, 1973.
mouse	LD50	subcutaneous	55mg/kg (55mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Proceedings of the Society for Experimental Biology and Medicine. Vol. 129, Pg. 284, 1968.
mouse	LDLo	oral	600mg/kg (600mg/kg)		Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rabbit	LD50	intravenous	12mg/kg (12mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 196, 1947.
rabbit	LD50	oral	115mg/kg (115mg/kg)		Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rat	LD50	intraperitoneal	11mg/kg (11mg/kg)		Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rat	LD50	oral	115mg/kg (115mg/kg)		Agricultural Research Service, USDA Information Memorandum. Vol. 20, Pg. 24, 1966.
rat	LDLo	intramuscular	33mg/kg (33mg/kg)		Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.

Potassium antimonyl tartrate sesquihydrate (CAS NO.28300-74-5) hasn't been listed as a carcinogen by NTP, IARC, ACGIH, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.

Consensus Reports

Antimony and its compounds are on the Community Right-To-Know List.

Safety Profile

Human poison by intravenous route, producing liver and kidney changes, somnolence, dyspnea, and pupillary dilation. Poison by ingestion, subcutaneous, intravenous, intramuscular, and intraperitoneal routes. Large doses cause severe liver damage. Human mutation data reported. Used medicinally, the therapeutic dose is close to the toxic dose. Upon decomposition it emits toxic fumes of K₂O and Sb.
Hazard Codes: Harmful Xn, Dangerous N
Risk Statements: 20/22-51/53
R20/22:Harmful by inhalation and if swallowed.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 61
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.

Standards and Recommendations

OSHA PEL: TWA 0.5 mg(Sb)/m³
ACGIH TLV: TWA 0.5 mg(Sb)/m³
NIOSH REL: (Antimony) TWA 0.5 mg(Sb)/m³
DOT Classification: 6.1; Label: KEEP AWAY FROM FOOD

Specification

Potassium antimonyl tartrate sesquihydrate , its cas register number is 28300-74-5. It also can be called Antimony potassium tartrate trihydrate ; and Antimonate(2-), bis(mu-(2,3-dihydroxybutanedioato(4-)-O1,O2:O3,O4))di-, dipotassium, trihydrate, stereoisomer . It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: first, should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly, get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While, it's inhaled: Remove from exposure and move to fresh air immediately. Give artificial respiration while not breathing. When breathing is difficult, give oxygen. And as soon as to get medical aid. Then you have the ingesting of the product: Get medical aid if irritation develops or persists. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid
In addition, Potassium antimonyl tartrate sesquihydrate (CAS NO.28300-74-5) could be stable under normal temperatures and pressures. It is not compatible with strong oxidizing agents, acids, bases, carbonates, and you must not take it with incompatible materials. And also prevent it to broken down into hazardous decomposition products: carbon monoxide, carbon dioxide, antimony/antimony oxides, oxides of potassium.