Products Categories
CAS No.: | 28789-35-7 |
---|---|
Name: | NORDIHYDROCAPSAICIN |
Article Data: | 5 |
Molecular Structure: | |
Formula: | C17H27 N O3 |
Molecular Weight: | 293.406 |
Synonyms: | Octanamide,7-methyl-N-vanillyl- (8CI); Nordihydrocapsaicin; Norhydrocapsaicin |
Density: | 1.036 g/cm3 |
Boiling Point: | 487 °C at 760 mmHg |
Flash Point: | 248.3 °C |
PSA: | 58.56000 |
LogP: | 4.01440 |
Conditions | Yield |
---|---|
In diethyl ether 1.) room temp., overnight, 2.) reflux, 3 h; Yield given; |
(Z)-N-(4-hydroxy-3-methoxybenzyl)-7-methyloct-5-enamide
Nordihydrocapsaicin
Conditions | Yield |
---|---|
With hydrogen; palladium on activated charcoal In ethanol under 760 Torr; for 4h; |
norcapsaicin
Nordihydrocapsaicin
Conditions | Yield |
---|---|
With hydrogen; palladium on activated charcoal In ethanol under 760 Torr; for 4h; |
isononoic acid
Nordihydrocapsaicin
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 1.) SOCl2 / 1.) room temp., 3 h, 2.) reflux, 2 h 2: diethyl ether / 1.) room temp., overnight, 2.) reflux, 3 h View Scheme |
7-methyl-6-oxooctanoic acid
Nordihydrocapsaicin
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 93 percent / KOH, N2H4*H2O / bis-(2-hydroxy-ethyl) ether / 23 h / Heating 2: 1.) SOCl2 / 1.) room temp., 3 h, 2.) reflux, 2 h 3: diethyl ether / 1.) room temp., overnight, 2.) reflux, 3 h View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: diethyl ether / 72 h / Ambient temperature 2: H2 / 10percent Pd/C / ethanol / 4 h / 760 Torr View Scheme | |
Multi-step reaction with 2 steps 1: diethyl ether / 72 h / Ambient temperature 2: H2 / 10percent Pd/C / ethanol / 4 h / 760 Torr View Scheme |
methyl 4-formylbutanoate
Nordihydrocapsaicin
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 1.) t-BuOK / 1.) DMF, RT, 5 min, 2.) a) RT, 20 h, b) 90 deg C, 1 h 2: aq. KOH / ethanol / 1 h / Heating 3: thionyl chloride / 1.) RT, 18 h, 2.) 100 deg C, 30 min 4: diethyl ether / 72 h / Ambient temperature 5: H2 / 10percent Pd/C / ethanol / 4 h / 760 Torr View Scheme | |
Multi-step reaction with 6 steps 2: Na(Hg), MeOH / tetrahydrofuran / 8 h / -20 °C 3: aq. KOH / ethanol / 1 h / Heating 4: thionyl chloride / 1.) RT, 18 h, 2.) 100 deg C, 30 min 5: diethyl ether / 72 h / Ambient temperature 6: H2 / 10percent Pd/C / ethanol / 4 h / 760 Torr View Scheme |
methyl 5-hydroxypentanoate
Nordihydrocapsaicin
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: pyridinium chlorochromate (PCC), sodium acetate / CH2Cl2 / 1.5 h / Ambient temperature 2: 1.) t-BuOK / 1.) DMF, RT, 5 min, 2.) a) RT, 20 h, b) 90 deg C, 1 h 3: aq. KOH / ethanol / 1 h / Heating 4: thionyl chloride / 1.) RT, 18 h, 2.) 100 deg C, 30 min 5: diethyl ether / 72 h / Ambient temperature 6: H2 / 10percent Pd/C / ethanol / 4 h / 760 Torr View Scheme | |
Multi-step reaction with 7 steps 1: pyridinium chlorochromate (PCC), sodium acetate / CH2Cl2 / 1.5 h / Ambient temperature 3: Na(Hg), MeOH / tetrahydrofuran / 8 h / -20 °C 4: aq. KOH / ethanol / 1 h / Heating 5: thionyl chloride / 1.) RT, 18 h, 2.) 100 deg C, 30 min 6: diethyl ether / 72 h / Ambient temperature 7: H2 / 10percent Pd/C / ethanol / 4 h / 760 Torr View Scheme |
(E)-7-Methyloct-5-enoic acid
Nordihydrocapsaicin
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: thionyl chloride / 1.) RT, 18 h, 2.) 100 deg C, 30 min 2: diethyl ether / 72 h / Ambient temperature 3: H2 / 10percent Pd/C / ethanol / 4 h / 760 Torr View Scheme |
(Z)-7-Methyl-oct-5-enoic acid
Nordihydrocapsaicin
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: thionyl chloride / 1.) RT, 18 h, 2.) 100 deg C, 30 min 2: diethyl ether / 72 h / Ambient temperature 3: H2 / 10percent Pd/C / ethanol / 4 h / 760 Torr View Scheme |