CAS No.291536-35-1,(Z)-5-(4-Fluorobenzylidene)thiazolidine-2,4-dione Suppliers

Products Categories

Pharmaceutical (17)
Others (6)
Organic Chemicals (4)

Basic Information

Molecular Structure:
CAS No.:	291536-35-1
Name:	(Z)-5-(4-Fluorobenzylidene)thiazolidine-2,4-dione
Article Data:	17

Formula:	C₁₀H₆FNO₂S
Molecular Weight:	223.228
Synonyms:	(Z)-5-(4-Fluorobenzylidene)-1,3-thiazolidine-2,4-dione;(Z)-5-(4-Fluorobenzylidene)thiazolidine-2,4-dione;
Density:	1.495 g/cm³
PSA:	74.96000
LogP:	2.42550

Synthetic route

: 2295-31-0
2,4-thiazolidinedion

: 459-57-4
4-fluorobenzaldehyde

: 291536-35-1
(Z)-5-(4-fluorophenylmethylene)-2,4-thiazolidinedione

Conditions

Conditions	Yield
With Fe3O4/SiO2-NH2/Cu(II) In ethanol for 0.5h; Catalytic behavior; Reflux; Green chemistry;	97%
With aluminum oxide at 108℃; for 0.0833333h; Microwave irradiation;	97%
With piperidine; acetic acid at 20℃; for 0.025h; Knoevenagel condensation; microwave irradiation;	95%

: 2295-31-0
2,4-thiazolidinedion

: sodium (4-fluorophenyl)(hydroxy)methanesulfonate

: 291536-35-1
(Z)-5-(4-fluorophenylmethylene)-2,4-thiazolidinedione

Conditions

Conditions	Yield
With trichlorophosphate In toluene for 8h; Reflux;	36%

: 459-57-4
4-fluorobenzaldehyde

: 291536-35-1
(Z)-5-(4-fluorophenylmethylene)-2,4-thiazolidinedione

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium hydrogensulfite / water; hexane / 1 h / 20 °C 2: trichlorophosphate / toluene / 8 h / Reflux View Scheme

: 444-27-9, 19291-02-2, 34592-47-7, 45521-09-3
(RS)-4-thiazolidinecarboxylic acid

: 291536-35-1
(Z)-5-(4-fluorophenylmethylene)-2,4-thiazolidinedione

: 82-86-0
acenaphthene quinone

: C25H17FN2O3S2

Conditions

Conditions	Yield
In ethanol at 25 - 30℃; for 5h; Sonication;	88%

...Expand

: 107-97-1
sarcosine

: 91-56-5
indole-2,3-dione

: 291536-35-1
(Z)-5-(4-fluorophenylmethylene)-2,4-thiazolidinedione

: 1-N-methyl-spiro[2.3']oxindole-spiro[3.5'']thiazoline-2'',4''-dione-4-(4-fluorophenyl)-pyrrolidine

Conditions

Conditions	Yield
In 1,4-dioxane; water Heating;	83%

...Expand

: 91-56-5
indole-2,3-dione

: 444-27-9, 19291-02-2, 34592-47-7, 45521-09-3
(RS)-4-thiazolidinecarboxylic acid

: 291536-35-1
(Z)-5-(4-fluorophenylmethylene)-2,4-thiazolidinedione

: C21H16FN3O3S2

Conditions

Conditions	Yield
In ethanol at 25℃; for 5h; Sonication; regioselective reaction;	80%

...Expand

: 96-32-2
bromoacetic acid methyl ester

: 291536-35-1
(Z)-5-(4-fluorophenylmethylene)-2,4-thiazolidinedione

: 438190-39-7
{5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-2,4-dioxo-thiazolidin-3-yl}-acetic acid methyl ester

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide Heating;	78%
Stage #1: (Z)-5-(4-fluorophenylmethylene)-2,4-thiazolidinedione With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.166667h; Stage #2: bromoacetic acid methyl ester In N,N-dimethyl-formamide for 24h;

: 135038-33-4
7-(4-(2-chloroacetyl)piperazin-1-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

: 291536-35-1
(Z)-5-(4-fluorophenylmethylene)-2,4-thiazolidinedione

: (Z)-1-ethyl-6-fluoro-7-(4-(2-(5-(4-fluorobenzylidene)-2,4-dioxothiazolidin-3-yl)acetyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Conditions

Conditions	Yield
With potassium carbonate; potassium iodide In acetone for 3h; Reflux;	68%

: 161798-25-0
4-(bromomethyl)-7-hydroxy-2H-chromen-2-one

: 291536-35-1
(Z)-5-(4-fluorophenylmethylene)-2,4-thiazolidinedione

: 1307299-72-4
(Z)-5-(4-fluorobenzylidene)-3-[(7-hydroxy-2-oxo-2H-chromen-4-yl)methyl]thiazolidine-2,4-dione

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 6h;	65%

: 291536-35-1
(Z)-5-(4-fluorophenylmethylene)-2,4-thiazolidinedione

: 5-(4-fluorophenylmethyl)-2,4-thiazolidinedione

Conditions

Conditions	Yield
With pyridine; lithium borohydride In tetrahydrofuran for 2.5h; Reduction; Heating;	62%

Country:
Business Type:
All

Lab/Research institutions

Trading Company

Manufacturers

Other
Certificate:
Manufacturer

Enterprise Authentication

ISO

GMP

FDA

HALAL

Display:default sort
Suppiers of more reward points first

New supplier

Total:26 Page 1 of 1 1

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 291536-35-1

Chemistry

Molecular Structure of 2,4-Thiazolidinedione,5-[(4-fluorophenyl)methylene]-, (5Z)- (CAS NO.291536-35-1):

Empirical Formula: C₁₀H₆FNO₂S
Molecular Weight: 223.2235
ACD/LogP: 1.45
of Rule of 5 Violations: 0
ACD/LogD (pH 5.5): 1.44
ACD/LogD (pH 7.4): 1.18
ACD/BCF (pH 5.5): 7.33
ACD/BCF (pH 7.4): 4.02
ACD/KOC (pH 5.5): 144.42
ACD/KOC (pH 7.4): 79.09
H bond acceptors: 3
H bond donors: 1
Freely Rotating Bonds: 1
Polar Surface Area: 62.68 ?2
Index of Refraction: 1.677
Molar Refractivity: 56.24 cm³
Molar Volume: 149.2 cm³
Surface Tension: 60.7 dyne/cm
Density: 1.495 g/cm³
SMILES: O=C1C(\SC(=O)N1)=C\c2ccc(F)cc2
InChI: InChI=1/C10H6FNO2S/c11-7-3-1-6(2-4-7)5-8-9(13)12-10(14)15-8/h1-5H,(H,12,13,14)/b8-5-

Specification

2,4-Thiazolidinedione,5-[(4-fluorophenyl)methylene]-, (5Z)- , with CAS number of 291536-35-1, can be called 5-(4-Fluoro-benzylidene)-thiazolidine-2,4-dione ; (5Z)-5-(4-fluorobenzylidene)-1,3-thiazolidine-2,4-dione .