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300-37-8

Basic Information
CAS No.: 300-37-8
Name: diodone
Molecular Structure:
Molecular Structure of 300-37-8 (diodone)
Formula: C7H5I2O3•C4H11NO2
Molecular Weight: 510.09
Synonyms: Diodona [INN-Spanish];Diatrast;Diodone;Pyelosil;Diodrast;Ioduron B;Methylglucamine 3,5-diiodo-4-pyridone N-acetate;Ethanol, 2,2-iminodi-, 3,5-diiodo-4-oxo-1(4H)-pyridineacetate (salt);Per-Radiographol;Diaethanolamin. 3,5-dijodpyridon-(4)-essigsaeure [German];Diodon;Neomethiodal;Xumbradil;1(4H)-Pyridineacetic acid, 3,5-diiodo-4-oxo-, compd. with 2,2-iminobis(ethanol) (1:1);Oparenol;Cardiotrast;Nosylan;Ethanol, 2,2-iminodi-, compd. with 3,5-diiodo-4-oxo-1(4H)-pyridineacetic acid (1:1);Bis(hydroxyethyl)ammonium 3,5-diiodo-4-pyridone-N-acetate;Vasiodone;Diodonum [INN-Latin];Iopyracil;Per-Abrodil;Iodopiraceti [DCIT];Savac;Nosydrast;Pylumbrin;bis(2-hydroxyethyl)azanium; 2-(3,5-diiodo-4-oxo-pyridin-1-yl)acetate;Neo-skiodan;RP 3203;1(4H)-Pyridineacetic acid, 3,5-diiodo-4-oxo-, compd. with 2,2-iminodiethanol (1:1);
EINECS: 206-089-4
Melting Point: 245-249°
Boiling Point: 422.8 °C at 760 mmHg
Flash Point: 209.5 °C
PSA: 111.79000
LogP: 0.09360
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Toxicity Data With Reference

1.   

ivn-rat LD50:5400 mg/kg

    AEPPAE    Naunyn-Schmiedebergs Archiv fuer Experimentelle Pathologie und Pharmakologie. 222 (1954),584.
2.   

ivn-mus LD50:6400 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 116 (1956),394.
3.   

ivn-dog LD50:2 g/kg

    BJRAAP    British Journal of Radiology. 6 (1933),304.
4.   

ivn-cat LD50:2800 mg/kg

    MECHAN    Medicinal Chemistry, A Series of Reviews. 6 (1963),344.
5.   

ivn-rbt LD50:4700 mg/kg

    MECHAN    Medicinal Chemistry, A Series of Reviews. 6 (1963),344.

Safety Profile

Moderately toxic by intravenous route. When heated to decomposition it emits very toxic fumes of NOx and I.