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331771-20-1

Basic Information
CAS No.: 331771-20-1
Name: Benzamide,N-[4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]-
Molecular Structure:
Molecular Structure of 331771-20-1 (Benzamide,N-[4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]-)
Formula: C29H31N5O4
Molecular Weight: 513.59
Synonyms: N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide;
EINECS:
Density: 1.282 g/cm3
Melting Point: 117-120 °C
Boiling Point: 639.671 °C at 760 mmHg
Flash Point: 340.661 °C
Solubility:
Appearance: Pale yellow solid
Hazard Symbols:
Risk Codes:
Safety:
Transport Information:
PSA: 97.84000
LogP: 4.81930
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Chemistry

Product Name: N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide
Synonyms of N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide (CAS NO.331771-20-1): ZM 447439
CAS NO: 331771-20-1
Molecular Formula of N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide (CAS NO.331771-20-1): C29H31N5O4
Molecular Weight: 513.5875
Molecular Structure:

Polar Surface Area: 97.84 Å2
Index of Refraction: 1.664
Molar Refractivity: 148.482 cm3
Molar Volume: 400.51 cm3
Surface Tension: 61.616 dyne/cm
Density of N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide (CAS NO.331771-20-1): 1.282 g/cm3
Flash Point: 340.661 °C
Enthalpy of Vaporization: 94.453 kJ/mol
Boiling Point: 639.671 °C at 760 mmHg

Uses

 N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide (CAS NO.331771-20-1) is a potent and selective inhibitor of Aurora B kinase. Cells treated with ZM-447439 progress through interphase, enter mitosis and assemble bipolar spindles but chromosome alignment, segregation and cytokinesis all fail.