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33817-20-8

Basic Information
CAS No.: 33817-20-8
Name: PIVAMPICILLIN
Article Data: 8
Molecular Structure:
Molecular Structure of 33817-20-8 (PIVAMPICILLIN)
Formula: C22H29 N3 O6 S
Molecular Weight: 463.555
Synonyms: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-, hydroxymethyl esterpivalate (ester), D-(-)- (8CI); 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl ester, [2S-[2a,5a,6b(S*)]]-;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl ester, (2S,5R,6R)- (9CI); Ampicillin pivaloyloxymethylester; Hydroxymethyl6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylatepivalate (ester); MK 191; Pivaloylampicillin; Pivaloyloxymethyl D-a-aminobenzylpenicillinate;Pivaloyloxymethyl ampicillinate; Pivampicillin
Density: 1.33g/cm3
Boiling Point: 679°Cat760mmHg
Flash Point: 364.5°C
PSA: 153.33000
LogP: 2.35260
Synthetic route

6β-((R)-2-azido-2-phenyl-acetylamino)-penicillanic acid 2,2-dimethyl-propionyloxymethyl ester

33817-20-8

pivampicillin

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal
18997-19-8

Chloromethyl pivalate

33817-20-8

pivampicillin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aq. NaI / acetone
2: H2 / Pd-C
View Scheme

6β-((R)-2-azido-2-phenyl-acetylamino)-penicillanic acid; potassium salt

33817-20-8

pivampicillin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aq. NaI / acetone
2: H2 / Pd-C
View Scheme
33817-20-8

pivampicillin

(2R,4S)-2-[(R)-((R)-2-Amino-2-phenyl-acetylamino)-carboxy-methyl]-5,5-dimethyl-thiazolidine-4-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester

Conditions
ConditionsYield
With phosphate buffer; penicillinamide β-lactamhydrolase at 25℃; Product distribution; Mechanism; enzymatic hydrolysis under various conditions;
33817-20-8

pivampicillin

69-53-4

ampicillin

Conditions
ConditionsYield
With phosphate buffer; sodium chloride In water at 37℃; half-life value, pH 7.4, other ampicillin esters;
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