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34642-77-8

Basic Information
CAS No.: 34642-77-8
Name: Amoxicillin sodium
Molecular Structure:
Molecular Structure of 34642-77-8 (Amoxicillin sodium)
Formula: C16H18N3NaO5S
Molecular Weight: 387.38
Synonyms: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[2-amino-2-(p-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-, monosodiumsalt, (-)- (8CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2R)-amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, monosodiumsalt, (2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt,[2S-[2a,5a,6b(S*)]]-;Amoxycillin sodium;Amoxycillin sodium salt;BRL 2333AB-B;Sodium amoxycillin;Sodium a-amino-p-hydroxybenzylpenicillin;
EINECS: 252-124-1
Density:
Melting Point: 130℃
Boiling Point: 743.2 °C at 760 mmHg
Flash Point: 403.3 °C
Solubility: Soluble in water.
Appearance: A White CRYSTALLINE powder
Hazard Symbols:
Risk Codes:
Safety:
Transport Information:
PSA: 161.09000
LogP: -0.28190
Raw Materials
26787-78-0
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  • Amoxicillin sodiumCAS NO.: 34642-77-8

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    Amoxicillin sodiumCAS NO.: 34642-77-8

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Chemistry

Molecular Structure:

Molecular Formula: C16H18N3NaO5S
Molecular Weight: 387.386
IUPAC Name: sodium (2S,5R,6R)-6-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Synonyms of Amoxicillin sodium (CAS NO.34642-77-8): Amoxicillin sodium [USAN] ; (2S-(2alpha,5alpha,6beta(S*)))-6-((Amino(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid monosodium salt ; (2S-(2alpha,5alpha.6beta(S*)))-6-((Amino(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid monosodium salt ; Acuotricina ; Agram IM ; Alfida ; Alfoxil Enjektabl ; Amitron ; Amoxicillin natrium ; BRL 23333AB-B ; Danoxillin ; Danoxillin [inj.] ; EINECS 252-124-1 ; Ibiamox ; Ibiamox [inj.] ; Lamoxy ; Lamoxy [inj.] ; Monosodium (-)-(2S,5R,6R)-6-((R)-2-amino(4-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate ; Monosodium (-)-(2S,5R,6R)-6-((R)-2-amino-2-(p-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate ; Moxacin ; Moxacin [inj.] ; Novabritine ; Novabritine [inj.] ; Penamox ; Penamox [inj.] ; Quimiopen ; Riotapen ; Riotapen [inj.] ; Trifamox ; UNII-544Y3D6MYH ; Sodium (2S-(2alpha,5alpha,6beta(S*)))-6-((amino(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate
CAS NO: 34642-77-8
Classification Code: Antibiotic ; Antibiotics
H bond acceptors: 8
H bond donors: 5
Freely Rotating Bonds: 6
Polar Surface Area: 115.69 Å2
Flash Point: 403.3 °C
Enthalpy of Vaporization: 113.73 kJ/mol
Boiling Point: 743.2 °C at 760 mmHg
Vapour Pressure: 3.39E-23 mmHg at 25°C

Uses

 Amoxicillin sodium (CAS NO.34642-77-8) can be used as broad-spectrum antibiotics metandienone. This quality produced by sterile crystallization is suitable for aseptic filling into vials, bottles or other delivery systems using any customary machine. A clear solution for injection is produced by adding water for injection.

Standards and Recommendations

Identification(HPLC): corresponding
Water content(Karl Fischer): not more than 2.0 %
visible particles: essentially free
subvisible particles: particles >= 10 μm: <= 6000/g; particles >= 25 μm: <= 600/g
pH: 8.0 - 10.0
2-Ethylhexanoic acid: not more than 0.8 %
Sterility: sterile
Bacterial endotoxins: not more than 0.03 IU
related substances: Individual: not more than 2.0 %; Dimer: not more than 3.0 %; Total: not more than 9.0 %
Assay/Content(HPLC): Clavulanic acid: 7.4 - 9.02 %; Amoxicillin: 73.8 - 90.2 %
Ratio: Amoxicillin/Clavulanic acid: 9.0 - 11.0 (w/w)

Specification

Storage of Amoxicillin sodium (CAS NO.34642-77-8):
Store between +2°C and +8°C, Protect from light and moisture