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CAS No.: | 34675-84-8 |
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Name: | CETRAXATE, HYDROCHLORIDE |
Article Data: | 2 |
Molecular Structure: | |
Formula: | C17H23 N O4 |
Molecular Weight: | 305.374 |
Synonyms: | Benzenepropanoicacid, 4-[[[4-(aminomethyl)cyclohexyl]carbonyl]oxy]-, trans-; Cetraxate;Tranexamic acid, p-(2-carboxyethyl)phenyl ester; p-(2-Carboxyethyl)phenyltrans-4-(aminomethyl)cyclohexanecarboxylate |
Density: | 1.182g/cm3 |
Melting Point: | melts over a range of 200-280° |
Boiling Point: | 480.9°Cat760mmHg |
Flash Point: | 244.6°C |
Safety: | Poison by intravenous route. Moderately toxic by intraperitoneal and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx. |
PSA: | 89.62000 |
LogP: | 3.07460 |
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IUPAC Name: 3-[4-[4-(Aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid
Synonyms of Cetraxate (CAS NO.34675-84-8) : Benzenepropanoic acid, 4-(((4-(aminomethyl)cyclohexyl)carbonyl)oxy)-, trans- ; Cetraxate ; Hydrocinnamic acid, p-hydroxy-, 4-(aminomethyl)cyclohexanecarboxylate, trans- ; trans-4-(((4-(Aminomethyl)cyclohexyl)carbonyl)oxy)benzenepropanoic acid
CAS NO:34675-84-8
Molecular Formula:C17H23NO4
Molecular Weight :305.3688
Molecular Structure :
Index of Refraction: 1.551
Surface Tension: 49.9 dyne/cm
Density: 1.182 g/cm3
Flash Point: 244.6 °C
Enthalpy of Vaporization: 78.52 kJ/mol
Boiling Point: 480.9 °C at 760 mmHg
Vapour Pressure: 4.67E-10 mmHg at 25°C
Cetraxate (CAS NO.34675-84-8) is an oral gastrointestinal medication which has a cytoprotective effect.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 1520mg/kg (1520mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980. | |
mouse | LD50 | intravenous | 681mg/kg (681mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980. | |
mouse | LD50 | subcutaneous | 4310mg/kg (4310mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980. | |
rat | LD50 | intraperitoneal | 716mg/kg (716mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980. | |
rat | LD50 | intravenous | 345mg/kg (345mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980. | |
rat | LD50 | subcutaneous | 1503mg/kg (1503mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980. |
Poison by intravenous route. Moderately toxic by intraperitoneal and subcutaneous routes. When Cetraxate (CAS NO.34675-84-8) is heated to decomposition, it emits toxic fumes of NOx.