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3562-63-8

Basic Information
CAS No.: 3562-63-8
Name: Megestrol
Article Data: 8
Molecular Structure:
Molecular Structure of 3562-63-8 (Megestrol)
Formula: C22H30O3
Molecular Weight: 342.478
Synonyms: 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione;
EINECS: 222-628-6
Density: 1.15 g/cm3
Melting Point: 207-208 °C(Solv: ethyl ether (60-29-7); acetone (67-64-1))
Boiling Point: 500.4 °C at 760 mmHg
Flash Point: 270.5 °C
Appearance: white solid
PSA: 54.37000
LogP: 4.00450
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Chemistry

IUPAC Name: Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-
The MF of Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl- (3562-63-8) is C22H30O3.

                                     
The MW of Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl- (3562-63-8) is 342.47.
Synonyms of Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl- (3562-63-8): Megestrol ; Megestrolo ; Megestrolum ; Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl- ; 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione
Index of Refraction: 1.569 
Density: 1.15 g/ml
Flash Point: 270.5 °C 
Boiling Point: 500.4 °C 
EINECS: 222-628-6

Uses

  Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl- (3562-63-8) is used for treat dysmenorrhea, dysfunctional uterine bleeding, endometriosis and endometrial adenocarcinoma.

Specification

Megestrol is a progesterone derivative with antineoplastic properties used in the treatment of advanced carcinoma of the breast and endometrium. When given in relatively high doses, Megestrol can substantially increase appetite in most individuals, even those with advanced cancer.
Megestrol Acetate Oral Suspension (a form of Megestrol) is used primarily as an appetite enhancer. The method of appetite enhancement is not known, but it can cause high blood sugar.
Currently, it is manufactured under the trade name Megace