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356560-84-4

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Basic Information
CAS No.: 356560-84-4
Name: 1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione
Article Data: 2
Molecular Structure:
Molecular Structure of 356560-84-4 (1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione)
Formula: C14H10N4O2
Molecular Weight: 266.259
Synonyms: 1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione;QC-1211;1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl);
EINECS: 1308068-626-2
Density: 1.39±0.1 g/cm3(Predicted)
PSA: 77.22000
LogP: 1.49830
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Synthetic route
614750-82-2

1-(6-methylpyridin-2-yl)-2-([1,2,4]triazolo[1,5-a]pyridin-6-yl)ethanone

356560-84-4

1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

Conditions
ConditionsYield
With hydrogen bromide; dimethyl sulfoxide at 60 - 70℃; for 2h;92%
With water; hydrogen bromide In dimethyl sulfoxide at 60 - 70℃; for 2h;
1122-72-1

6-methyl-2-pyridinecarboxaldehyde

356560-84-4

1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: ziconium(IV) oxychloride octahydrate / 1 h / 20 °C
2.1: caesium carbonate / isopropyl alcohol; tetrahydrofuran / 20 °C
2.2: 1 h
2.3: pH 7 - 8
3.1: dimethyl sulfoxide; hydrogen bromide / 2 h / 60 - 70 °C
View Scheme
614750-85-5

diphenyl (6-methylpyridin-2-yl)(phenylamino)methylphosphonate

356560-84-4

1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: caesium carbonate / isopropyl alcohol; tetrahydrofuran / 20 °C
1.2: 1 h
1.3: pH 7 - 8
2.1: dimethyl sulfoxide; hydrogen bromide / 2 h / 60 - 70 °C
View Scheme
356560-84-4

1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

51673-84-8

dimethoxyacetaldehyde

1352609-89-2

6-(2-(dimethoxymethyl)-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine

Conditions
ConditionsYield
With ammonium acetate In methanol; tert-butyl methyl ether; water at 20℃; for 4h;83%
With ammonium acetate In methanol; tert-butyl methyl ether; water at 20℃; for 4h;83%
Stage #1: 1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione; dimethoxyacetaldehyde With ammonium acetate In methanol; tert-butyl methyl ether; water at 20℃; for 3h;
Stage #2: With sodium hydrogencarbonate In methanol; tert-butyl methyl ether; water pH=8;		78%
2913-97-5

N-phthalimidyl-2-aminoacetaldehyde

356560-84-4

1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

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2-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)isoindoline-1,3-dione

Conditions
ConditionsYield
With ammonium acetate In methanol; tert-butyl methyl ether at 20 - 50℃; for 10h;67%
356560-84-4

1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

2120-70-9

2-phenoxyethanal

1352609-80-3

6-(5-(6-methylpyridin-2-yl)-2-(phenoxymethyl)-1H-imidazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine

Conditions
ConditionsYield
With ammonium acetate In methanol; tert-butyl methyl ether at 20℃; for 1.16667h; Inert atmosphere;56%
With ammonium acetate In methanol; tert-butyl methyl ether at 20℃; Inert atmosphere;56%
356560-84-4

1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

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2-(phenylthio)acetaldehyde

1352609-84-7

6-(5-(6-methylpyridin-2-yl)-2-((phenylthio)methyl)-1H-imidazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine

Conditions
ConditionsYield
With ammonium acetate In methanol; tert-butyl methyl ether at 20℃; for 1.16667h; Inert atmosphere;38%
With ammonium acetate In methanol; tert-butyl methyl ether at 20℃; Inert atmosphere;38%
3382-18-1

6,7-dimethoxy-3,4-dihydro-isoquinoline

356560-84-4

1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

C25H22N6O2

Conditions
ConditionsYield
With ammonium acetate; acetic acid In tert-butyl methyl ether Heating / reflux;37%
356560-84-4

1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

109346-98-7

3-cyanophenyl-1-acetaldehyde

1352610-23-1

3-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)benzonitrile

Conditions
ConditionsYield
Stage #1: 1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione; 3-cyanophenyl-1-acetaldehyde With ammonium acetate In methanol; tert-butyl methyl ether at 20℃; for 1.5h; Inert atmosphere;
Stage #2: With sodium hydrogencarbonate In methanol; tert-butyl methyl ether; water pH=8; Inert atmosphere;		33%
356560-84-4

1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

1248456-74-7

2-((2-fluorophenyl)(methyl)amino)acetaldehyde

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N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-fluoro-N-methylaniline

Conditions
ConditionsYield
Stage #1: 1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione; 2-((2-fluorophenyl)(methyl)amino)acetaldehyde With ammonium acetate In methanol; tert-butyl methyl ether at 20℃; for 2h; Inert atmosphere;
Stage #2: With sodium hydrogencarbonate In methanol; tert-butyl methyl ether; water pH=8; Inert atmosphere;		32%
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    1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

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    1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

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  • 1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

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    1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

    Min.Order: 0

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    1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dioneAppearance:detailed see specifications Storage:Store in dry, dark and ventilated place Package:foil bags, drums or bottles Application:Pharmaceutical Intermediates Transpo

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  • 356560-84-4

  • Casno:

    356560-84-4

    356560-84-4

    Min.Order: 0

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    Shanghai Chinqesen Biotechnology Co., Ltd. Company slogan:?Innovation, cooperation and win-win Company introduction:?Shanghai Chinqesen Biotechnology Co., Ltd. is a professional ph

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  • 1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

  • Casno:

    356560-84-4

    1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

    Min.Order: 0

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    factory?direct?sale Application:Fine chemical intermediates, used as the main raw material for the synthesis of various pesticides, medicines, surfactants, polymer monomers, and antifungal agents

    We are a team of industry experts, dedicated to delivering the best chemical solutions from quality suppliers across China. Putting our customers first, we take a holistic approach

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    China (Mainland)  |  Contact Details

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  • 1-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

  • Casno:

    356560-84-4

    1-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

    Min.Order: 0

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    Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

    Bide Pharmatech Ltd., founded in 2007, focuses on the field of organic chemistry by providing organic reagents, functional materials, biochemical reagents and bulk drug intermediat

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     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:021-61629020

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  • 1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

  • Casno:

    356560-84-4

    1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

    Min.Order: 10 Milligram

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    1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

    Founded in 2011, Amadis Chemical Company Limited is an innovative manufacturer of chemical products and technical service providers. Our business includes sales, manufacture, and s

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     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-571-89925085

    Address:Watts Cosine.No.166.Xiangmao Road.

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