Products Categories
| CAS No.: | 36052-24-1 |
|---|---|
| Name: | Methyl 6-aminonicotinate |
| Article Data: | 30 |
| Molecular Structure: | |
|
|
|
| Formula: | C7H8N2O2 |
| Molecular Weight: | 152.153 |
| Synonyms: | Nicotinicacid, 6-amino-, methyl ester (6CI,8CI);2-Amino-5-(methoxycarbonyl)pyridine;3-Pyridinecarboxylicacid, 6-amino-, methyl ester;6-Aminopyridine-3-carboxylic acid methylester;Methyl 2-aminopyridine-5-carboxylate;6-Aminonicotinic acid methyl ester;Methyl6-aminopyridine-3-carboxylate; |
| EINECS: | 629-051-2 |
| Density: | 1.238 g/cm3 |
| Melting Point: | 158-162 °C(lit.) |
| Boiling Point: | 304.5 °C at 760 mmHg |
| Flash Point: | 137.9 °C |
| Appearance: | off-white solid |
| Hazard Symbols: |
 Xi,  Xn
|
| Risk Codes: | 36/37/38-20/21/22 |
| Safety: | 26-36-36/37 |
| Transport Information: | UN 2811 |
| PSA: | 65.21000 |
| LogP: | 1.03160 |
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 68439-39-4Poly(oxy-1,2-ethanediyl), alpha-(2-ethylhexyl)-omega-hydroxy-,
- 852475-26-4MC1568
| Conditions | Yield |
|---|---|
| With hydrogenchloride for 18h; Reflux; | 98% |
| With thionyl chloride at 80℃; for 12h; Inert atmosphere; | 89% |
| With sulfuric acid at 0 - 80℃; | 81.5% |
- 3167-49-5
6-aminonicotinic acid
- 18107-18-1
diazomethyl-trimethyl-silane
- 36052-24-1
methyl 6-aminonicotinoate
| Conditions | Yield |
|---|---|
| In methanol; chloroform; cyclohexane at 20℃; for 1h; | 66% |
| With acetic acid In methanol; chloroform |
- 21550-48-1
6-(acetylamino)pyridine-3-carboxylic acid
- 36052-24-1
methyl 6-aminonicotinoate
| Conditions | Yield |
|---|---|
| With hydrogenchloride; methanol |
- 1603-41-4
(5-methyl-pyridin-2-yl)amine
- 36052-24-1
methyl 6-aminonicotinoate
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: acetic acid 2: aqueous KMnO4 3: methanol; HCl View Scheme |
- 4931-47-9
N-(5-methylpyridin-2-yl)acetamide
- 36052-24-1
methyl 6-aminonicotinoate
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: aqueous KMnO4 2: methanol; HCl View Scheme |
- 3167-49-5
6-aminonicotinic acid
- 36052-24-1
methyl 6-aminonicotinoate
| Conditions | Yield |
|---|---|
| With hydrogenchloride In methanol; water | |
| With sulfuric acid In methanol; water-EtOAc | |
| With thionyl chloride In methanol; water |
| Conditions | Yield |
|---|---|
| In hydrogenchloride; methanol; water |
| Conditions | Yield |
|---|---|
| In hydrogenchloride; methanol; water | |
| In hydrogenchloride; methanol; water | |
| In hydrogenchloride; methanol; water | |
| In hydrogenchloride; methanol; water | |
| In hydrogenchloride; methanol; water |
| Conditions | Yield |
|---|---|
| In methanol |
- 36052-24-1
methyl 6-aminonicotinoate
- 24424-99-5
di-tert-butyl dicarbonate
- 144186-11-8
methyl 6-<(tert-butyloxycarbonyl)amino>nicotinoate
| Conditions | Yield |
|---|---|
| With dmap In tetrahydrofuran at 20℃; | 100% |
| With dmap In acetonitrile for 4h; Ambient temperature; | 79% |
| With dmap In acetone; tert-butyl alcohol for 20h; | 78% |
What can I do for you?
Get Best Price
Chemistry
The molecular structure of 6-Aminonicotinic acid methyl ester (CAS NO.36052-24-1):
IUPAC Name: Methyl 6-aminopyridine-3-carboxylate
Molecular Weight: 152.15062 g/mol
Molecular Formula: C7H8N2O2
Density: 1.238 g/cm3
Melting Point: 158-162 °C(lit.)
Boiling Point: 304.5 °C at 760 mmHg
Flash Point: 137.9 °C
Index of Refraction: 1.57
Molar Refractivity: 40.35 cm3
Molar Volume: 122.8 cm3
Surface Tension: 53.4 dyne/cm
Enthalpy of Vaporization: 54.48 kJ/mol
Vapour Pressure: 0.000872 mmHg at 25 °C
XLogP3: 1.7
H-Bond Donor: 1
H-Bond Acceptor: 4
Rotatable Bond Count: 2
Tautomer Count: 4
Exact Mass: 152.058578
MonoIsotopic Mass: 152.058578
Topological Polar Surface Area 65.2
Heavy Atom Count 11
Canonical SMILES: COC(=O)C1=CN=C(C=C1)N
InChI: InChI=1S/C7H8N2O2/c1-11-7(10)5-2-3-6(8)9-4-5/h2-4H,1H3,(H2,8,9)
InChIKey: JACPDLJUQLKABC-UHFFFAOYSA-N
Product Categories: Amines; blocks; Carboxes; Pyridines; pharmacetical; Esters; Heterocycles; Heterocyclic Building Blocks
Uses
6-Aminonicotinic acid methyl ester (CAS NO.36052-24-1) is used in ointments for treatment of psoriasis.
Safety Profile
Hazard Codes: 
Xi, 
Xn
Risk Statements: 36/37/38-20/21/22
R36/37/38:Irritating to eyes, respiratory system and skin.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36-36/37
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S36/37:Wear suitable protective clothing and gloves.
RIDADR: 2811
WGK Germany: 3
Hazard Note: Irritant
HazardClass: IRRITANT
Specification
6-Aminonicotinic acid methyl ester (CAS NO.36052-24-1) is also named as 3-Pyridinecarboxylic acid, 6-amino-, methyl ester ; 6-Amino-nicotinic acid methyl ester ; Methyl 6-aminonicotinate ; Methyl 2-amino-5-pyridinecarboxylate ; Methyl 2-aminopyridine-5-carboxylate ; Methyl 6-Aminopyridine-3-carboxylate . 6-Aminonicotinic acid methyl ester (CAS NO.36052-24-1) is off-white solid.