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| CAS No.: | 367-27-1 |
|---|---|
| Name: | 2,4-Difluorophenol |
| Article Data: | 23 |
| Molecular Structure: | |
|
|
|
| Formula: | C6H4F2O |
| Molecular Weight: | 130.094 |
| Synonyms: | Phenol, 2,4-difluoro-; |
| EINECS: | 206-688-0 |
| Density: | 1.351 g/cm3 |
| Melting Point: | 22.4 °C(lit.) |
| Boiling Point: | 145.7 °C at 760 mmHg |
| Flash Point: | 56.7 °C |
| Solubility: | slightly soluble in water |
| Appearance: | clear yellow-green liquid after melting |
| Hazard Symbols: |
 Xn,  Xi,  C,  F
|
| Risk Codes: | 20/21/22-37/38-41-34-11-36/37/38 |
| Safety: | 26-36/37/39-45-16 |
| Transport Information: | UN 1992 |
| PSA: | 20.23000 |
| LogP: | 1.67040 |
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Chemistry
MF: C6H4F2O
MW: 130.09
EINECS: 206-688-0
2,4-Difluoro phenol,its melting pont is about 22.4 °C(lit.);boiling point is 52-53 °C at 19 mm Hg(lit.);density is 1.362 g/mL at 25 °C(lit.).
Following is the molecular structure of 2,4-Difluoro phenol:
Uses
Pesticides, pharmaceuticals and dye intermediates.
Toxicity Data With Reference
Acute toxicity: not available.
Safety Profile
Hazard Codes :Xn,Xi,C,F (Harmful;Irritant;Corrosive;Highly Flammable)
Risk Statements :
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed
R41:Risk of serious damage to eyes
R34:Causes burns
R11:Highly Flammable
R36/37/38 :Irritating to eyes, respiratory system and skin
Safety Statements :
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
S16 :Keep away from sources of ignition - No smoking
Specification
2,4-Difluorophenol, is an organic building block used for the synthesis of various pharmaceutical compounds, such as antivirulence agents. It is also used in the synthesis of new α-Phenoxyacetamide derivatives, acting as type III secretion system of Pseudomonas aeruginosa PAO1, a gram-negative bacteria.