Welcome to LookChem.com Sign In|Join Free
  • or
Home > Pharmaceutical > 3680 > 

3680-69-1

Basic Information
CAS No.: 3680-69-1
Name: 7H-Pyrrolo[2,3-d]pyrimidine,4-chloro-
Molecular Structure:
Molecular Structure of 3680-69-1 (7H-Pyrrolo[2,3-d]pyrimidine,4-chloro-)
Formula: C6H4ClN3
Molecular Weight: 153.57
Synonyms: 1H-Pyrrolo[2,3-d]pyrimidine,4-chloro- (7CI,9CI);4-Chloro-7H-pyrrolo[2,3-d]pyrimidine;6-Chloro-7-deazapurine;NSC 64952;7H-Pyrrolo(2,3-d)pyrimidine, 4-chloro-;4-Chloropyrrolo[2,3-d]pyrimidine;
EINECS: 628-079-2
Density: 1.531 g/cm3
Melting Point: 183-184 °C
Boiling Point: 325.9 °C at 760 mmHg
Flash Point: 180.7 °C
Solubility:
Appearance: light brown to brown crystalline powder
Hazard Symbols: IrritantXi,ToxicT,HarmfulXn
Risk Codes: 36/37/38-25-20/21/22
Safety: 26-37-45-36
Transport Information: UN 2811 6.1/PG 3
PSA: 41.57000
LogP: 1.61130
Synthetic route
3680-71-5

Allopurinol

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With chlorine In 1-methyl-pyrrolidin-2-one; toluene at 160 - 180℃; Temperature;95%
With 1,2,3-trichloropropane; chlorine In 1-methyl-pyrrolidin-2-one; toluene Reflux;95%
With dmap; bis(trichloromethyl) carbonate In chlorobenzene at 50 - 60℃; for 6h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;94.2%

6-chloro-5-(2-methoxyvinyl)pyrimidin-4-ylamine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran; water at 20℃; for 7.5h; Reflux;94%
Stage #1: 6-chloro-5-(2-methoxyvinyl)pyrimidin-4-ylamine With hydrogenchloride; water In tetrahydrofuran at 20℃; Reflux;
Stage #2: With sodium hydrogencarbonate In tetrahydrofuran; water at 20℃; for 1h;
With hydrogenchloride In tetrahydrofuran; water for 7.5h; Reflux;54.5 g
3680-71-5

7-deazahypoxanthine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With trichlorophosphate for 2h; Reflux;93%
With trichlorophosphate92%
With trichlorophosphate for 4h; Reflux;91%

4-hydroxypyrrolo[2,3-D]pyrimidine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With trichlorophosphate for 3h; Reflux;93%

4-amino-6-chloro-5-(2,2-diethoxyethyl)pyrimidine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With hydrogenchloride In water at 50℃; for 4h; Reagent/catalyst;92%
With hydrogenchloride; water In Petroleum ether at 50℃; for 4h;91%

4-amino-6-chloropyrimidine-5-acetaldehyde

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With hydrogenchloride In methanol; water at 50℃; for 3h; Concentration; Temperature; Industrial scale;91.4%
With hydrogenchloride In methanol; water at 50 - 60℃; for 3h;82%
With acetic acid at 20℃; for 14h;26.1 g

1,1-dichloro-2-cyano-4-methoxy-1,3-butadiene

6313-33-3

formamidine hydrochloride

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With sodium methylate In methanol at 25 - 70℃; for 10h;91%

1,1-dichloro-2-cyano-4-methoxy-1,3-butadiene

3473-63-0

formamidine acetic acid

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With sodium methylate In methanol at 30 - 70℃; for 10h;90.2%
123148-78-7

4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With potassium benzo[d][1,3]dioxol-5-yltrifluoroborate; PdCl2(1,1'-bis(diphenylphosphino)ferrocene); triethylamine In ethanol; dichloromethane for 19h; Reagent/catalyst; Reflux;90%
3680-71-5

1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With trichlorophosphate at 100℃; for 5h;65.7%
With trichlorophosphate for 5h; Reflux;54%
With trichlorophosphate for 5h; Reflux;54%
With trichlorophosphate for 5h; Reflux;54%
16019-33-3

2-(4,6-dichloropyrimidin-5-yl)acetaldehyde

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With ammonium hydroxide at 60 - 70℃; for 24h;34%
Multi-step reaction with 3 steps
1: toluene-4-sulfonic acid / ethanol / 2 h / 40 °C
2: ammonium hydroxide / ethanol / 20 h / 70 °C
3: hydrogenchloride; water / Petroleum ether / 4 h / 50 °C
View Scheme
Multi-step reaction with 3 steps
1: toluene-4-sulfonic acid / ethanol / 3 h / 40 °C
2: ammonium hydroxide / 3 h / 60 °C
3: hydrogenchloride / water / 4 h / 50 °C
View Scheme
52133-67-2

ethyl 2-cyano-4,4-diethoxybutyrate

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 64 percent / NaOEt
2: 92 percent / aq. HCl
3: 81 percent / H2 / Raney Ni
4: 66 percent / POCl3
View Scheme
Multi-step reaction with 3 steps
1: NaOEt / ethanol
2: 1.) Raney-Nickel; 2.) HCl
3: POCl3
View Scheme
Multi-step reaction with 4 steps
1: 64 percent / EtONa / dimethylformamide; ethanol / 6 h / Heating
2: aq. NH3 / Raney nickel / 6 h / Heating
3: 86 percent / 1N aq. HCl / 1 h / 20 °C
4: 79 percent / POCl3 / 1.5 h / Heating
View Scheme
7400-05-7

6-amino-5-(2,2-diethoxyethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 92 percent / aq. HCl
2: 81 percent / H2 / Raney Ni
3: 66 percent / POCl3
View Scheme
Multi-step reaction with 3 steps
1: aq. NH3 / Raney nickel / 6 h / Heating
2: 86 percent / 1N aq. HCl / 1 h / 20 °C
3: 79 percent / POCl3 / 1.5 h / Heating
View Scheme
Multi-step reaction with 3 steps
1: hydrogenchloride / water / 22 h
2: ammonium hydroxide / water / 72 h / Reflux
3: trichlorophosphate / 5 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1.1: hydrogenchloride / water
2.1: ammonium hydroxide / water
2.2: raney nickel / 5 h / 100 °C
3.1: trichlorophosphate / 5 h / 100 °C
View Scheme
67831-84-9

2-thioxo-1,2,3,7-tetrahydro-4H-pyrrolo[2,3-d]pyrimidin-4-one

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 81 percent / H2 / Raney Ni
2: 66 percent / POCl3
View Scheme
Multi-step reaction with 2 steps
1: ammonium hydroxide / water / 72 h / Reflux
2: trichlorophosphate / 5 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: ammonium hydroxide / water
1.2: raney nickel / 5 h / 100 °C
2.1: trichlorophosphate / 5 h / 100 °C
View Scheme
7400-05-7

6-amino-5-(2,2-diethoxy)-2-mercaptopyrimidine-4-ol

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) Raney-Nickel; 2.) HCl
2: POCl3
View Scheme
Multi-step reaction with 3 steps
1: ammonia / nickel / water / 90 °C
2: hydrogenchloride; water / 2.5 h / 20 °C
3: trichlorophosphate / 2.5 h / 100 °C
View Scheme
Multi-step reaction with 3 steps
1: nickel / water / 1 h / Heating / reflux
3: trichlorophosphate / 1.5 h / Heating / reflux
View Scheme
7400-06-8

4-amino-6-hydroxy-5-(2,2-diethoxyethyl)pyrimidine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 86 percent / 1N aq. HCl / 1 h / 20 °C
2: 79 percent / POCl3 / 1.5 h / Heating
View Scheme
3680-71-5

7-deazahypoxanthine

A

4-CHLORO-5,7-DIHYDRO-PYRROLO[2,3-D]PYRMIDIN-6-ONE

4-CHLORO-5,7-DIHYDRO-PYRROLO[2,3-D]PYRMIDIN-6-ONE

B

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With trichlorophosphateA 49 mg (70%)
B n/a
7400-06-8

6-amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogenchloride / water / 2.5 h / 20 °C
2: trichlorophosphate / 2.5 h / 100 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: hydrogenchloride / water / 4 h / 25 - 30 °C
2: trichlorophosphate / 1 h / 100 - 105 °C
View Scheme
Multi-step reaction with 2 steps
1: hydrogenchloride; water / 2.5 h / 20 °C
2: trichlorophosphate / 2.5 h / 100 °C
View Scheme
Multi-step reaction with 2 steps
2: trichlorophosphate / 1.5 h / Heating / reflux
View Scheme

6-amino-5-(2,2-diethoxyethyl)-2-mercaptopyrimidin-4-ol

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: ammonia / water / 90 °C
2: hydrogenchloride / water / 2.5 h / 20 °C
3: trichlorophosphate / 2.5 h / 100 °C / Inert atmosphere
View Scheme
1615680-91-5

6-chloro-5-((trimethylsilyl)ethynyl)pyrimidin-4-amine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With 1-methyl-pyrrolidin-2-one; potassium tert-butylate at 90℃; for 0.833333h;505 mg
16019-31-1

5-allyl-4,6-dichloropyrimidine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: ammonium hydroxide / ethanol / 24 h / 60 °C / Industrial scale
2: ozone / methanol / -30 °C / Industrial scale
3: hydrogenchloride / methanol; water / 3 h / 50 °C / Industrial scale
View Scheme
Multi-step reaction with 2 steps
1: ozone / methanol; dichloromethane / 2 h / -40 °C
2: ammonium hydroxide / 24 h / 60 - 70 °C
View Scheme
Multi-step reaction with 3 steps
1: ammonium hydroxide / ethanol / 24 h / 70 °C / Sealed tube
2: triethylamine; dimethyl sulfoxide; ozone / methanol / 2 h / -5 - 0 °C
3: acetic acid / 14 h / 20 °C
View Scheme
773076-83-8

2-cyano-4,4-dimethoxybutyric acid ethyl ester

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium ethanolate / ethanol / Reflux
2: hydrogenchloride / water / 45 °C
3: trichlorophosphate; N-ethyl-N,N-diisopropylamine / toluene / 50 °C
View Scheme

6-amino-5-(2,2-dimethoxyethyl)pyrimidin-4-ol

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogenchloride / water / 45 °C
2: trichlorophosphate; N-ethyl-N,N-diisopropylamine / toluene / 50 °C
View Scheme
16019-30-0

5-(prop-2-en-1-yl)pyrimidine-4,6-diol

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: N,N-dimethyl-aniline; trichlorophosphate / acetonitrile / 3 h / 80 °C / Inert atmosphere
2: ozone / methanol; dichloromethane / 2 h / -40 °C
3: ammonium hydroxide / 24 h / 60 - 70 °C
View Scheme
Multi-step reaction with 4 steps
1: N,N-dimethyl-aniline; trichlorophosphate / acetonitrile / 3 h / 80 °C / Inert atmosphere
2: ammonium hydroxide / ethanol / 24 h / 70 °C / Sealed tube
3: triethylamine; dimethyl sulfoxide; ozone / methanol / 2 h / -5 - 0 °C
4: acetic acid / 14 h / 20 °C
View Scheme
Multi-step reaction with 5 steps
1: N,N-dimethyl-aniline; trichlorophosphate / acetonitrile / 3 h / 80 °C / Inert atmosphere
2: ozone / methanol; dichloromethane / 2 h / -40 °C
3: toluene-4-sulfonic acid / ethanol / 2 h / 40 °C
4: ammonium hydroxide / ethanol / 20 h / 70 °C
5: hydrogenchloride; water / Petroleum ether / 4 h / 50 °C
View Scheme
14052-82-5

4,6-dichloro-5-(2,2-diethoxyethyl)pyrimidine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ammonium hydroxide / ethanol / 20 h / 70 °C
2: hydrogenchloride; water / Petroleum ether / 4 h / 50 °C
View Scheme
40637-56-7

dimethyl allylmalonate

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium methylate / methanol / 5 h / 0 - 60 °C
2: N,N-dimethyl-aniline; trichlorophosphate / acetonitrile / 3 h / 80 °C / Inert atmosphere
3: ozone / methanol; dichloromethane / 2 h / -40 °C
4: ammonium hydroxide / 24 h / 60 - 70 °C
View Scheme
Multi-step reaction with 5 steps
1: sodium methylate / methanol / 5 h / 0 - 60 °C
2: N,N-dimethyl-aniline; trichlorophosphate / acetonitrile / 3 h / 80 °C / Inert atmosphere
3: ammonium hydroxide / ethanol / 24 h / 70 °C / Sealed tube
4: triethylamine; dimethyl sulfoxide; ozone / methanol / 2 h / -5 - 0 °C
5: acetic acid / 14 h / 20 °C
View Scheme
Multi-step reaction with 6 steps
1: sodium methylate / methanol / 5 h / 0 - 60 °C
2: N,N-dimethyl-aniline; trichlorophosphate / acetonitrile / 3 h / 80 °C / Inert atmosphere
3: ozone / methanol; dichloromethane / 2 h / -40 °C
4: toluene-4-sulfonic acid / ethanol / 2 h / 40 °C
5: ammonium hydroxide / ethanol / 20 h / 70 °C
6: hydrogenchloride; water / Petroleum ether / 4 h / 50 °C
View Scheme
67831-84-9

2-mercapto-4-hydroxy-7H-pyrrolo[2,3-d]pyrimidine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium hydroxide; dihydrogen peroxide / water / 2 h / 15 - 20 °C
2: hydrogenchloride / water / 1 h
3: trichlorophosphate / 85 °C
View Scheme

C10H19N3O3S

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: hydrogenchloride / water / 20 °C / pH 2 - 3
2: sodium hydroxide; dihydrogen peroxide / water / 2 h / 15 - 20 °C
3: hydrogenchloride / water / 1 h
4: trichlorophosphate / 85 °C
View Scheme
3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

74-89-5

methylamine

78727-16-9

4-(methylamino)-7H-pyrrolo<2,3-d>pyrimidine

Conditions
ConditionsYield
In ethanol at 100℃; for 2h; Sealed tube;100%
With hydrogenchloride In methanol for 6h; Heating;85%
3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

123148-78-7

4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With N-iodo-succinimide; sodium sulfate In ethanol; N,N-dimethyl-formamide100%
With N-iodo-succinimide; sodium sulfate In ethanol; N,N-dimethyl-formamide100%
With N-iodo-succinimide; sodium sulfate In ethanol; N,N-dimethyl-formamide100%
916177-00-9

(5-(methoxycarbonyl)-1-tosyl-1H-pyrrol-3-yl)boronic acid

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1-(toluene-4-sulfonyl)-1H-pyrrole-2-carboxylic acid methyl ester

Conditions
ConditionsYield
With potassium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 170℃; for 0.166667h; Microwave irradiation;100%
956460-98-3

4-tert-butoxycarbonylamino-piperidine-4-carboxylic acid ethyl ester

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

956460-97-2

4-tert-butoxycarbonylamino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-piperidine-4-carboxylic acid ethyl ester

Conditions
ConditionsYield
With triethylamine In 1-methyl-pyrrolidin-2-one at 110℃; for 68h;100%
With triethylamine In 1-methyl-pyrrolidin-2-one at 110℃; for 68h;100%
With triethylamine In 1-methyl-pyrrolidin-2-one at 110℃; for 68h;100%
3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

870706-50-6

4-chloro-7-triisopropylsilanyl-7H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Stage #1: 4-chloro-1H-pyrrolo[2,3-d]pyrimidine With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 5.5h;
Stage #2: With water; ammonium chloride In tetrahydrofuran; hexane
100%
3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

1100318-96-4

4-iodo-7H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With hydrogen iodide In water at 20℃; for 80h; Inert atmosphere;100%
With hydrogen iodide at 20℃; for 80h; Inert atmosphere;98%
With hydrogen iodide In water at 20℃; for 48h;91%
76513-69-4

(2-trimethylethylsilylethoxy)methyl chloride

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

941685-26-3

4-chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrole[2,3-d]pyrimidine

Conditions
ConditionsYield
Stage #1: 4-chloro-1H-pyrrolo[2,3-d]pyrimidine With sodium hydride In N,N-dimethyl-formamide at 20℃; for 1h; Cooling with ice;
Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In N,N-dimethyl-formamide Cooling with ice;
100%
Stage #1: 4-chloro-1H-pyrrolo[2,3-d]pyrimidine With sodium hydride In N,N-dimethyl-formamide at 20℃; for 1h; Cooling with ice;
Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In N,N-dimethyl-formamide for 1h; Cooling with ice;
100%
Stage #1: 4-chloro-1H-pyrrolo[2,3-d]pyrimidine With sodium hydride In N,N-dimethyl-formamide; mineral oil at 10℃; for 1h; Cooling with ice; Inert atmosphere;
Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In N,N-dimethyl-formamide; mineral oil at 10 - 20℃;
97%
13154-24-0

triisopropylsilyl chloride

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

870706-50-6

4-chloro-7-triisopropylsilanyl-7H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
Stage #1: 4-chloro-1H-pyrrolo[2,3-d]pyrimidine With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere;
Stage #2: triisopropylsilyl chloride In tetrahydrofuran; hexane at -78 - 20℃; for 4.5h; Inert atmosphere;
100%
Stage #1: 4-chloro-1H-pyrrolo[2,3-d]pyrimidine With sodium hydride In tetrahydrofuran; mineral oil at 0 - 6.8℃; for 0.916667h; Inert atmosphere;
Stage #2: triisopropylsilyl chloride In tetrahydrofuran; mineral oil at 0℃; for 4h; Inert atmosphere; Reflux;
99%
942185-01-5

1H-pyrazolo[3,4-b]pyridin-5-amine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

N-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazolo[3,4-b]pyridin-5-amine

Conditions
ConditionsYield
With hydrogenchloride In ethanol; water for 6h; Reflux;100%

(+/-)-cis-4-methyl-1-(phenylmethyl)-piperidin-3-ylamine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

cis-1-benzyl-4-methyl-N-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidin-3-amine

Conditions
ConditionsYield
With potassium carbonate In water at 100℃; for 48h; Sealed tube;100%
309956-78-3

(R)-piperidin-3-ylcarbamic acid tert-butyl ester

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

(R)-tert-butyl (1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl)carbamate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In butan-1-ol at 80℃; for 52h; Inert atmosphere; Sealed tube;100%

tert-butyl N-methyl-N-[(3R,4R)-4-methylpiperidin-3-yl]carbamate

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

C18H27N5O2

Conditions
ConditionsYield
With potassium carbonate In 1,4-dioxane; water at 100℃; for 10h;100%

(R)-N-methyl-5-((R)-1-phenylethyl)-5-azaspiro[2.4]heptan-7-amine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

N-methyl-N-((R)-5-((R)-1-phenylethyl)-5-azaspiro[2.4]heptan-7-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Conditions
ConditionsYield
With potassium carbonate In water for 18h; Reflux;100%

benzyl (3S,4R)-3-methyl-1,6-diazaspiro[3.4]octane-1-carboxylate oxalate

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

benzyl (3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octane-1-carboxylate

Conditions
ConditionsYield
With potassium phosphate In ethanol; water at 40 - 80℃; for 5h; Inert atmosphere;100%
With potassium phosphate In ethanol; water at 80℃; for 5h; Inert atmosphere;
With potassium phosphate In ethanol; water at 80℃; for 5h; Temperature; Inert atmosphere;
3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

22276-95-5

5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With N-Bromosuccinimide In acetonitrile at 100℃; for 0.166667h; microwave irradiation;99%
With N-Bromosuccinimide In N,N-dimethyl-formamide at 20℃; for 12h;95%
With N-Bromosuccinimide In N,N-dimethyl-formamide at 20℃; for 72h;95%
100-60-7

N-methylcyclohexylamine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

252722-30-8

N-cyclohexyl-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Conditions
ConditionsYield
In 1,4-dioxane at 110℃; for 9h; Microwave irradiation; Sealed tube;99%
Stage #1: N-methylcyclohexylamine; 4-chloro-1H-pyrrolo[2,3-d]pyrimidine In tert-butyl alcohol at 100℃; for 24h;
Stage #2: With hydrogenchloride In water; tert-butyl alcohol pH=1;
Stage #3: With sodium hydroxide In water; tert-butyl alcohol pH=14;
88%
In tert-butyl alcohol at 85℃;
3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

57260-71-6

1-t-Butoxycarbonylpiperazine

4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With RuPhos palladacycle; lithium hexamethyldisilazane; ruphos In tetrahydrofuran at 65℃; for 4h; Inert atmosphere; Sealed vial;99%
With triethylamine In butan-1-ol at 90℃;74%
With triethylamine In N,N-dimethyl-formamide at 110℃; for 16h;59%
1153949-15-5

tert-butyl 3-(cyanomethyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidine-1-carboxylate

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

1,1-dimethylethyl 3-(cyanomethyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-1-azetidinecarboxylate

Conditions
ConditionsYield
With [1,1′-bis(di-cyclohexylphosphino)ferrocene]dichloro palladium(II); cesium fluoride In water; tert-butyl alcohol Suzuki Coupling; Inert atmosphere; Reflux;99%
With [1,1′-bis(di-cyclohexylphosphino)ferrocene]dichloropalladium (II); cesium fluoride In water; tert-butyl alcohol Inert atmosphere; Reflux;99%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,4-dioxane; water for 1h; Reflux;

2-(1-(ethanesulfonyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidine-3-yl)acetonitrile

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

1187594-09-7

Baricitinib

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,4-dioxane; water at 80 - 85℃; for 5h;99%
With tetrakis(triphenylphosphine) palladium(0); cesium fluoride In water; toluene; tert-butyl alcohol at 100℃; for 48h; Concentration; Temperature; Solvent; Reagent/catalyst; Suzuki Coupling; Inert atmosphere;90%
With potassium phosphate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In tetrahydrofuran; water at 90℃; for 19h; Autoclave; Inert atmosphere;90%
With tetrakis(triphenylphosphine) palladium(0); cesium fluoride In water; toluene; tert-butyl alcohol for 48h; Suzuki Coupling; Reflux; Inert atmosphere;84%
960-16-7

tributylphenylstannane

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

1168106-39-5

4-phenyl-7H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With 1,8-Cineole; bis-triphenylphosphine-palladium(II) chloride; triphenyl-arsane at 100℃; for 32h; Stille Cross-Coupling (Migita-Kosugi-Stille Coupling);99%

t-butyl (3S,4R)-3-methyl-1,6-diazaspiro[3.4]octane-1-carboxylate

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

t-butyl (3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octane-1-carboxylate

Conditions
ConditionsYield
With potassium carbonate In water at 110℃; for 4h;99%
18997-19-8

Chloromethyl pivalate

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

1146629-75-5

(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl 2,2-dimethylpropanoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 14h;98.85%
Stage #1: 4-chloro-1H-pyrrolo[2,3-d]pyrimidine With sodium hydride In tetrahydrofuran at 0 - 20℃; Inert atmosphere;
Stage #2: Chloromethyl pivalate In tetrahydrofuran at 0 - 20℃; Inert atmosphere;
91%
Stage #1: 4-chloro-1H-pyrrolo[2,3-d]pyrimidine With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; Inert atmosphere;
Stage #2: Chloromethyl pivalate In tetrahydrofuran; mineral oil at 0 - 20℃; Product distribution / selectivity; Inert atmosphere;
91%
98-09-9

benzenesulfonyl chloride

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

186519-89-1

4-chloro-7-(phenylsulfonyl)-7H-pyrrolo [2,3-d]pyrimidine

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 0 - 20℃;98%
With sodium hydride at 0 - 25℃; for 4h;98%
With sodium t-butanolate In tetrahydrofuran at 10 - 22℃; for 2h;92%
110-89-4

piperidine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

94581-94-9

4-(piperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With silver trifluoromethanesulfonate In N,N-dimethyl-formamide at 90℃;98%
With potassium hydroxide In water at 100℃; under 750.075 Torr; for 0.166667h; Microwave irradiation;84%
In tert-butyl alcohol at 85℃; for 3h;60%
In tert-butyl alcohol at 100℃; for 0.166667h; Microwave irradiation;
367-21-5

3-chloro-4-fluorophenylamine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

346600-33-7

(3-chloro-4-fluoro-phenyl)-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine

Conditions
ConditionsYield
With silver trifluoromethanesulfonate In N,N-dimethyl-formamide at 90℃;98%
57946-56-2

2-fluoro-4-chloroaniline

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

865364-20-1

(4-chloro-2-fluoro-phenyl)-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine

Conditions
ConditionsYield
With silver trifluoromethanesulfonate In N,N-dimethyl-formamide at 90℃;98%
54060-30-9

3-acetylenephenylamine

3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

186519-85-7

(3-ethynyl-phenyl)-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine

Conditions
ConditionsYield
With silver trifluoromethanesulfonate In N,N-dimethyl-formamide at 90℃;98%
3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

271-70-5

7H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With hydrogen; palladium 10% on activated carbon In methanol under 760.051 Torr; for 16h;98%
With ammonium formate; 20% Pd(OH)2 on carbon In methanol for 2h; Heating / reflux;97%
With hydrogen; palladium on activated charcoal84%
With ammonium hydroxide; hydrogen; palladium on activated charcoal In ethanol at 20℃; for 6h;83.7%
With hydrogen; palladium 10% on activated carbon In methanol at 20℃;
3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

98-59-9

p-toluenesulfonyl chloride

479633-63-1

4-chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine

Conditions
ConditionsYield
With sodium hydroxide In water; acetone at 0 - 20℃; for 6h;97%
With dmap; triethylamine In dichloromethane at 0 - 20℃; for 0.5h; Large scale;97.7%
With dmap; triethylamine In dichloromethane at 0 - 20℃; Industrial scale;97.7%
3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

74-88-4

methyl iodide

7781-10-4

4-Chlor-7-methyl-7H-pyrrolo<2,3-d>pyrimidin

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 4h;97%
With caesium carbonate In DMF (N,N-dimethyl-formamide) at 20℃; for 1h;94%
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 6h;88%
  • Display:default sort

    New supplier

  • 4-Chloropyrrolo[2,3-d]pyrimidine Manufacturer/High quality/Best price/In stock

  • Casno:

    3680-69-1

    MSDS/COA Download

    4-Chloropyrrolo[2,3-d]pyrimidine Manufacturer/High quality/Best price/In stock

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 3.0-3.0/Kilogram

    Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

    Dayang Chem (Hangzhou) Co.,Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredi

  •  Dayang Chem (Hangzhou) Co.,Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-88938639

    Address:9/F, Unit 2 Changdi Torch Building, 259# WenSan Road, Xihu District, Hangzhou City 310012, P.R.China

       Inquiry Now

  • 4-chloro-7H-pyrrolo[2,3-d]pyrimidine 99% 3680-69-1

  • Casno:

    3680-69-1

    4-chloro-7H-pyrrolo[2,3-d]pyrimidine 99% 3680-69-1

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    1,8 years exporting experience; 2.Competitive price and quality; 3,Free sample can be provided; 4,We are sincerely responsible for the"sample quality" , "product quality" and "After Service"; 5. prom

    Enbridge PharmTech Co., Ltd. is an innovative company integrated with R&D, manufacturing, marketing and distribution of intermediates and fine chemicals, mainly used to pharmaceuti

  •  EnBridge PharmTech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-510-83591909

    Address:Huishan Zone, Wuxi City, Jiangsu Province, P.R.China

       Inquiry Now

  • 4-Chloropyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    MSDS/COA Download

    4-Chloropyrrolo[2,3-d]pyrimidine

    Min.Order: 100 Gram

    FOB Price:  USD $ 10.0-10.0/Gram

    Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

    Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,an

  •  Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:0086-317-5105699

    Address:40# Shuiyuesi Street, Cangzhou City,Hebei Province, China.

       Inquiry Now

  • 4-chloro-7H-pyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    4-chloro-7H-pyrrolo[2,3-d]pyrimidine

    Min.Order: 50 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    High quality / commercialize; 200kg in stock; Stable production capacity. Wit Pharma is a high-tech pharmaceutical company integrating R&D, production and sales, which is committed to the research and development of small molecule pharmac

    Wit Pharma is a high-tech pharmaceutical company integrating R&D, production and sales, which is committed to the research and development of small molecule pharmaceutical intermed

  •  Nanjing Zhiyan Pharmaceutical Technology Co. Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-18602559219

    Address:Nanjing

       Inquiry Now

  • 3680-69-1 7H-Pyrrolo[2,3-d]pyrimidine,4-chloro-

  • Casno:

    3680-69-1

    3680-69-1 7H-Pyrrolo[2,3-d]pyrimidine,4-chloro-

    Min.Order: 1 Gram

    FOB Price:  USD $ 40.0-50.0/Gram

    1.good quality 1) good quality is the basic of our goal; 2) we can offer samples to be tested; 3) 98% of our products have exported to uk, usa, germany, spain, australia, middle east and many other countries. 4) Good feedback of quality from our cu

    Mulei (Wuhan) New Material Technology Co. Ltd is a scientific and technological company integrating product research and development, manufacture and trading of chemical intermedia

  •  WUHAN MULEI NEW MATERIAL CO., LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8619831967063

    Address:Office1201#, Block C, Hanjie Headquarters International Plaza, Zhongbei Rd, Wuchang District, Wuhan

       Inquiry Now

  • 4-Chloropyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    4-Chloropyrrolo[2,3-d]pyrimidine

    Min.Order: 10 Gram

    FOB Price:  USD $ 560.0-600.0/Gram

    CAS NO. 3680-69-1 4 - Chloropyrrolo English name [2, 3 - d] pyrimidine Chinese name 4 - chlorine pyrrole and pyrimidine Molecular formula C6H4ClN3 The molecular weight of 153.57 Specifications/purity 99% Supply capacity Appearance:white powde

    Hebei yanxi chemical co. LTD. has expanded a compositive entity from initially only as a small manufacturer. The company dedicated to the development, production and marketing of

  •  Hebei yanxi chemical co.,LTD.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:86-0311-66561638

    Address:Zhang zhe, guangzong county, xingtai city, hebei province

       Inquiry Now

  • High quality 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Cas 3680-69-1 with best price

  • Casno:

    3680-69-1

    High quality 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Cas 3680-69-1 with best price

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Unique advantages of 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Cas 3680-69-1 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White to almost white powder Storage:Cool dry pla

    Wuhan Fortuna Chemical Co., Ltd, located in the predominant Wu Han City where is a traffic hinge of China, is a big integrative chemical enterprise being engaged in producing and

  •  Wuhan Fortuna Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-27-59207852

    Address:A2705,Dong Yi Shi Qu,129# XinHua Road,WuHan,China

       Inquiry Now

  • 4-Chloro-1H-pyrrolo(2,3-d)pyrimidine

  • Casno:

    3680-69-1

    4-Chloro-1H-pyrrolo(2,3-d)pyrimidine

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

    Located in Zhengdong New District,?Zhengzhou of Henan province, Henan Allgreen Chemical Co.,Ltd is a comprehensive high-tech modern enterprises integrating professional R&D, pro

  •  Henan Allgreen Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-0371-87507775

    Address:No 260 Dongming Road,Jinshui District

       Inquiry Now

  • 4-Chloropyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    4-Chloropyrrolo[2,3-d]pyrimidine

    Min.Order: 10 Gram

    FOB Price:  USD $ 1.0-1.0/Gram

    Superiority: Hebei Huanhao Biotechnology co., Ltd. specializing in the production of research and development of pharmaceutical intermediates, this kind of products with high quality price concessions,welcomed the new and old customers advisory

    Hebei Yingong New Material Technology Co.,Ltd is one of the most dynamic research and advanced technology companies.We now have the most complete range of pharmaceutical intermedia

  •  Hebei Yingong New Material Technology Co.,Ltd .

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-18034554576

    Address:Shijiazhuang

       Inquiry Now

  • 4-Chloropyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    4-Chloropyrrolo[2,3-d]pyrimidine

    Min.Order: 10 Milligram

    FOB Price:  USD $ 0.0-0.0/Milligram

    1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

    Founded in 2011, Amadis Chemical Company Limited is an innovative manufacturer of chemical products and technical service providers. Our business includes sales, manufacture, and s

  •  Amadis Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-571-89925085

    Address:Watts Cosine.No.166.Xiangmao Road.

       Inquiry Now

  • 4-Chloropyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    4-Chloropyrrolo[2,3-d]pyrimidine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA.Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Active pharmaceutical ingredients(APIs), Veterinary, Indole derivatives, Aro

    Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Fine chemicals, Active pharmaceutical ingredients(APIs), Veterinary, In

  •  Chemwill Asia Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:021-51086038

    Address:High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China

       Inquiry Now

  • 6-Chloro-7-deazapurine

  • Casno:

    3680-69-1

    6-Chloro-7-deazapurine

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 1.0-1.0/Kilogram

    Product Name: 4-Chloropyrrolo[2,3-d]pyrimidine Synonyms: 4-Chloro-1H-pyrrolo[2,3-d]pyrimidine; 6-Chloro-7-deazapurine; 4-chloro-7H-pyrrolo[2,3-d]pyrimidine; 4-methyl-1,3-thiazole-2,5-diamine

    Welcome to Henan Sinotech! Sinotech Corporation has exceptional sourcing ability for chemicals used in Organic Fine Chemicals and APIs; Inorganic chemicals; Flame Retardants;OLED

  •  Henan Sinotech Import&Export Corporation

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-371-86181678

    Address:No. 260, Dongming Road,Jinshui District

       Inquiry Now

  • 4-Chloropyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    4-Chloropyrrolo[2,3-d]pyrimidine

    Min.Order: 1 Gram

    FOB Price:  USD $ 34.0-34.0/Gram

    Product Description

    Jinan Finer Chemical Co., Ltd is established under the support of Jinan city government, so it has many advantages in company credibility, finance safe, product quality control and

  •  Jinan Finer Chemical Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-531-88989536

    Address:New Material Industry Park, Jinan Ciyt, China

       Inquiry Now

  • Cheap 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine 100kg in stock

  • Casno:

    3680-69-1

    Cheap 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine 100kg in stock

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    TianYuan Pharmaceutical Co.,Limited was established in December 2009 for Hongkong. We are a leading high-tech enterprise expertised in researching, developing and manufacturing innovative and generic drugs on anticancer, anti-HIV, anti-tumor, an

    Tianyuan pharmaceutical company in Zhangjiang Eastern has built 500 square meters of pilot laboratories, equipped with two sets of 50L glass reactor, four sets of 100L double react

  •  Shenzhen Tianyuan Pharmaceutical Technology Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-755-23284190

    Address:B302,2 unit, Jin Lian Building, No. 134 Qianjin 2 Road, Taoyuan village, Xixiang Street, Baoan,Shenzhen,China

       Inquiry Now

  • 4-Chloropyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    4-Chloropyrrolo[2,3-d]pyrimidine

    Min.Order: 1 Gram

    FOB Price:  USD $ 1.0-1.0/Gram

    Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&

    LIDE PHARMACEUTICALS LIMITED is one of the fastest growing pharmaceutical company in China. We have developed strategic partnership with our manufacturing associates having state o

  •  LIDE PHARMACEUTICALS LIMITED

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-25-58409506

    Address:11F, Building A1, No.288 North Zhongshan Road, Gulou District, Nanjing,210003, P.R.China.

       Inquiry Now

  • best offer 4-Chloropyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    best offer 4-Chloropyrrolo[2,3-d]pyrimidine

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    4-Chloropyrrolo[2,3-d]pyrimidine Basic information Product Name: 4-Chloropyrrolo[2,3-d]pyrimidine Synonyms: 4-CHLORO-1H-PYRROLO(2,3-D)PYRIMIDINE;4-CHLOROPYRROLO[2,3-D]PYRIMIDINE;4-CHLORO

    Our company engages in Electronic chemicals such as OLED,Photoresist chemical,Electrolyte additive and Intermediate Pharmaceutical production; development of noble metal catalysts,

  •  Henan Tianfu Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-371-55170693/55170694

    Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China

       Inquiry Now

  • 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine  CAS 3680-69-1

  • Casno:

    3680-69-1

    4-Chloro-7H-pyrrolo[2,3-d]pyrimidine CAS 3680-69-1

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

    Hubei Xinrunde Chemical Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s)

  •  Hubei XinRunde Chemical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+8618874586545

    Address:No.43, Xinandu Industrial Park, East and West Lake District, Wuhan, Hubei, China

       Inquiry Now

  • New production CAS 3680-69-1 with best quality

  • Casno:

    3680-69-1

    New production CAS 3680-69-1 with best quality

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 139.0-210.0/Kilogram

    WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

    Zhuo Zhou Wen Xi Import and Export Co., Ltd. is a company mainly engaged in the export of pharmaceutical raw materials. Its parent company is (Wen Xi Pharma), including three subs

  •  Zhuozhou Wenxi import and Export Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-13111626072

    Address:Room 1710, Baoxin International Phase I, 19 Guanyun East Road, Zhuozhou, Hebei

       Inquiry Now

  • 7H-Pyrrolo[2,3-d]pyrimidine,4-chloro-

  • Casno:

    3680-69-1

    MSDS/COA Download

    7H-Pyrrolo[2,3-d]pyrimidine,4-chloro-

    Min.Order: 10 Gram

    FOB Price:  USD $ 10.0-1000.0/Gram

    7H-Pyrrolo[2,3-d]pyrimidine,4-chloro- 1) Quick Response Within 12 hours; 2) Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc.

    HUBEI AOKS BIO-TECH CO.,LTD is located in Hubei province of China.We specialized in Active pharmaceutical ingredient,pharmaceutical intermediates,veterinary drug intermediates and

  •  HUBEI AOKS BIO-TECH CO.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-27-52345788

    Address:28F,China Construction Third Bureau,Wuhan,Hubei Province, China

       Inquiry Now

  • Competitive Price CAS 3680-69-1  4-Chloropyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    Competitive Price CAS 3680-69-1 4-Chloropyrrolo[2,3-d]pyrimidine

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    1.High quality and competetive price 1)we are manufacturer with own lab and factory, can provide high quality products with factory price. 2)products purity is test by our quality department strictly before sending, and you can also ask

    We are Hebei miaobian Biotechnology Co., Ltd , mainly deal in pharmaceutical intermediates and various chemicals. It is with a registered capital of 3 million yuan, is one of the m

  •  Hebei miaobian Biotechnology Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:15032793961

    Address:Federal Business Plaza, Qiaoxi District,Shijiazhuang

       Inquiry Now

  • High purity 4-Chloropyrrolo[2,3-d]pyrimidine CAS No.:3680-69-1

  • Casno:

    3680-69-1

    High purity 4-Chloropyrrolo[2,3-d]pyrimidine CAS No.:3680-69-1

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 2.0-2.0/Kilogram

    4-Chloropyrrolo[2,3-d]pyrimidine CAS No.:3680-69-1 Name: 4-Chloropyrrolo[2,3-d]pyrimidine Synonyms: 4-Chloro-1H-pyrrolo[2,3-d]pyrimidine; 6-Chloro-7-deazapurine

    HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketi

  •  Hangzhou Think Chemical Co. Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-571-89986307/81956191/81956084/81956192

    Address:Room 719 Building D Meidu Plaza 789 Moganshan Road

       Inquiry Now

  • 7H-Pyrrolo[2,3-d]pyrimidine,4-chloro- 3680-69-1

  • Casno:

    3680-69-1

    7H-Pyrrolo[2,3-d]pyrimidine,4-chloro- 3680-69-1

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

    Shanghai Upbio Tech Co.,Ltd (Former Onchem (China)Co.,Ltd) is a comprehensive manufacturer and an international distribution of chemicals throughout the world, The predecessor of

  •  Shanghai Upbio Tech Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-52196435

    Address:No.2 Floor,No.979 Yunhan Rd,Nicheng,Pudong New Area,Shanghai,China

       Inquiry Now

  • 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine CAS 3680-69-1

  • Casno:

    3680-69-1

    4-Chloro-7H-pyrrolo[2,3-d]pyrimidine CAS 3680-69-1

    Min.Order: 0 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    1. Rich experience. Our company is a professional production leading factory in China in pharmaceutical area of many years, our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other country,

    Hubei Jusheng Technology Co., Ltd., is a large group corporation which engaged in the R&D and manufacture of chemicals, Pharmaceuticals and intermediates. We have earned ourselves

  •  Hubei Jusheng Technology Co., Ltd.,

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-18871490254

    Address:High-tech Industrial Park,Tianmen city,Hubei province.

       Inquiry Now

  • 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 130.0-154.0/Kilogram

    Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

    Baoji Guokang Healthchem co.,ltd located in Baoji High-tech Zone,is epitomizing international,cooperative and honest.We are a young company full of action and energy,and our profes

  •  Baoji Guokang Healthchem co.,ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-917-3909592

    Address:China

       Inquiry Now

  • Nice Quality 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Cas No: 3680-69-1

  • Casno:

    3680-69-1

    MSDS/COA Download

    Nice Quality 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Cas No: 3680-69-1

    Min.Order: 10 Gram

    FOB Price:  USD $ 1.0-3.0/Gram

    Our Service: 1. Best quality in your requirement 2. Competitive price in china market 3. Mature technical support 4. Professional logistic support 5 . Full experience of large numberscontainers loading in chinese sea port 6 .Fast

    Wuhan Monad Medicine Tech Co.,LTD is a research and development, production, sales in one high-tech company, own about 100 kinds of products, can provide about more than 30000 kind

  •  Wuhan Monad Medicine Tech Co.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8613397160123

    Address:13th Floor, Tower B, Century Plaza, Zhongnan Road, Wuchang District, Wuhan, China.

       Inquiry Now

  • 4-Chloropyrrolo[2,3-d]pyrimidine CAS NO.3680-69-1

  • Casno:

    3680-69-1

    4-Chloropyrrolo[2,3-d]pyrimidine CAS NO.3680-69-1

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,

    Changchun Artel Import and Export Trade Co., Ltd. is located in Changchun City, Jilin Province. It is a high-tech modern private enterprise specializing in the research, developme

  •  Changchun Artel lmport and Export trade company

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-0431-80543058

    Address:Dianshi Plazza,Chaoyang District

       Inquiry Now

  • 7H-Pyrrolo[2,3-d]pyrimidine,4-chloro- factory

  • Casno:

    3680-69-1

    7H-Pyrrolo[2,3-d]pyrimidine,4-chloro- factory

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers. Our advantages:1, High quality with competitive price:1) Standard:BP/USP/EP/Enterprise standard2) All Purity≥99%3) We are manufacturer

    Shaanxi Mingqi Chemical Co., Ltd is committed to the development of import and export trade in the production, operation and plant extracts of pharmaceutical raw materials and inte

  •  Shaanxi Mingqi Chemical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:18092428356

    Address:Weiyang District

       Inquiry Now

  • 7H-Pyrrolo[2,3-d]pyrimidine,4-chloro-3680-69-1

  • Casno:

    3680-69-1

    7H-Pyrrolo[2,3-d]pyrimidine,4-chloro-3680-69-1

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 178.0-188.0/Kilogram

    Name:Jilin Tely Imp & Exp Co., Ltd √ Verified Category:LLC (Ltd Liability Corp) Trade Category: Trading Company√ Verified Registered Time: 2016 √ Verified Registered Capital: US$101 Thousand - US$500 Thousa

    We, Jilin Tely Imp & Exp Co., Ltd. mainly supply and export products including: pharmaceutical raw materials,Chemical reagents, Food additives, pharmaceutical and pesticide interme

  •  Jilin Tely Imp.& Exp.Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-0431-81915458

    Address:Room 302, 47 Changping Street, Chaoyang District, Changchun, Jilin Province,China

       Inquiry Now

  • 4-Chloropyrrolo[2,3-d]pyrimidine  Tofacitinib citrate CAS NO.3680-69-1

  • Casno:

    3680-69-1

    4-Chloropyrrolo[2,3-d]pyrimidine Tofacitinib citrate CAS NO.3680-69-1

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 1.0-9999.0/Kilogram

    Changzhou Pesan Chemical Co., Ltd. is a dynamic and professional chemical company. Since its establishment, We provide raw materials and intermediates for the pharmaceutical industry and organic electronic materials. All of our staff have a chem

    Changzhou Pesan Chemical Co., Ltd. is a dynamic and specialized chemical company. Since our establishment, We provide raw materials and key intermediates for pharmaceutical industr

  •  Changzhou Pesan Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+86 021 61559630

    Address:No.7-9,Guanghua St.,Zhonglou District,Changzhou,China

       Inquiry Now

  • 4-Chloropyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    4-Chloropyrrolo[2,3-d]pyrimidine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

    Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, special chemicals and OLED materials &

  •  Xiamen Hisunny Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:86-592-3327115

    Address:Unit 603,No.879,Xiahe Road,Meixin Building,Xiamen,China

       Inquiry Now

  • 6-Chloro-7-deazapurin

  • Casno:

    3680-69-1

    6-Chloro-7-deazapurin

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 150.0-150.0/Kilogram

    Career Henan Chemical focus on high complex new type intermediates and fine chemical custom synthesis,scale-up production and rare chemicals. Product category including intermediates&api,catalyst and electronic chemicals. We have our R&

    Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded t

  •  Career Henan Chemical Co

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-371-86658258

    Address:Building 3 of Innovation Park, East District of the National University Science Park

       Inquiry Now

  • 4-Chloro-1H-pyrrolo(2,3-d)pyrimidine

  • Casno:

    3680-69-1

    4-Chloro-1H-pyrrolo(2,3-d)pyrimidine

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Betterbiochem is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in

    Shanghai BetterBioChem Co., Ltd. specializes in research, production of APIs, building blocks and key pharmaceutical intermediates. We provide our products from milligrams to kilog

  •  Shanghai BetterBioChem Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-18013506594

    Address:No. 8 Building, 18 nong, Xi Yingnan Road, Pudong, Shanghai,China

       Inquiry Now

  • 4-chloro-7,7a-dihydro-4aH-pyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    4-chloro-7,7a-dihydro-4aH-pyrrolo[2,3-d]pyrimidine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Wuhan Sun-shine Bio-technology Corporation Limited is specializing in the anticancer, antitumor,heart head blood-vessel,pharmaceutical intermediates,fine Chemicals production and customization. Company has strong ability of research and development

    Wuhan Sun-shine Bio-technology Corporation Limited (Shanghai Sun-shine Chemical Technology Corporation Limited) is a high-tech enterprise engaged inR&D and sales of related compoun

  •  Wuhan Sun-shine Bio-technology Corporation Limited

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-27-65522452

    Address:No. 388 Gaoxin Road(No. 2), East Lake Hi-tech Development Zone, Wuhan, Hubei Province, PRC

       Inquiry Now

  • 4-Chloropyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    4-Chloropyrrolo[2,3-d]pyrimidine

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    4-Chloropyrrolo[2,3-d]pyrimidine CAS:3680-69-1 (1)professional manufacturer (2)competitive price and first-grade quality (3)good service Appearance:White crystal powder Storage:Store in dry, dark and ventilated place. Package:Aluminum foil ba

    Shandong Bolode BIO-Technology Co.LTD is a professional company which engaged in the R&D and manufacture of Pharmaceuticals intermediates and Chemical Raw materials. The company is

  •  Shandong Bolode Bio-Technology Co., LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-0531-58966870

    Address:136 Jingyi Road,Huaiyin District,Jinan,Shandong,China

       Inquiry Now

  • 4-Chloropyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    4-Chloropyrrolo[2,3-d]pyrimidine

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Name: Tofacitinib intermediate Other name:4-Chloropyrrolo[2,3-d]pyrimidine Purity: 98% Stock:Fesh CAS No.:3680-69-1 Standard: In-house Application:It is the intermediate of Tofacitinib. Port:FOB China

    Hangzhou Jinlan Pharm-Drugs Technology Co.,Ltd is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pudon

  •  Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+86-571-85829053

    Address:Rm A606, Fuyi Center, jianqiao street, Jianggan Area

       Inquiry Now

  • 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

  • Casno:

    3680-69-1

    MSDS/COA Download

    4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 160.0-160.0/Kilogram

    in stock Assay:99% white powder dentification(HPLC) :The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the Conformal standard preparation, as obtained in the ass

    Wuhan Yingyuanbei Biotechnology Co., Ltd. is a high-tech enterprise specializing in R&D and production of pharmaceutical raw materials and intermediates. At present, t

  •  Wuhan Ying Yuan Bei Biological Limited

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-13349903920

    Address:Wuhan

       Inquiry Now

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Chemistry

IUPAC Name: 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
Systematic of 4-chloro-7H-pyrrolo[2,3-d]pyrimidine (CAS NO.3680-69-1): 4-Chloropyrrolo(2,3-d)pyrimidine ; BRN 0607871 ; NSC 64952 ; 7H-Pyrrolo(2,3-d)pyrimidine, 4-chloro-
CAS NO: 3680-69-1
Classification Code: Drug / Therapeutic Agent
Molecular Formula of 4-chloro-7H-pyrrolo[2,3-d]pyrimidine (CAS NO.3680-69-1): C6H4ClN3
Molecular Weight: 153.5691
Molecular Structure:

ProductCategories: Heterocycles ; Heterocycles series ; Halides ; Pyrimidine ; Heterocyclic Compounds ; Biochemistry ; Nucleobases and their analogs ; Nucleosides, Nucleotides & Related Reagents ; CHIRAL CHEMICALS ; Naphthyridine,Quinoline ; Bases & Related Reagents ; Intermediates ; Nucleotides ; Fused Ring Systems ; Heterocyclic Building Blocks
Melting Point: 183-184°C
Polar Surface Area: 30.71 Å2
Index of Refraction: 1.72
Molar Refractivity: 39.6 cm3
Molar Volume: 100.2 cm3
Surface Tension: 74.7 dyne/cm
Density of 4-chloro-7H-pyrrolo[2,3-d]pyrimidine (CAS NO.3680-69-1): 1.531 g/cm3
Flash Point: 180.7 °C
Enthalpy of Vaporization: 54.55 kJ/mol
Boiling Point: 325.9 °C at 760 mmHg
Vapour Pressure: 0.000424 mmHg at 25°C

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 297mg/kg (297mg/kg)   Gann. Japanese Journal of Cancer Research. Vol. 56, Pg. 219, 1965.

Safety Profile

Hazard Codes: IrritantXi,ToxicT,Xn
Risk Statements: 36/37/38-25-20/21/22 
R36/37/38: Irritating to eyes, respiratory system and skin. 
R25: Toxic if swallowed. 
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-37-45-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S37: Wear suitable gloves. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36: Wear suitable protective clothing.
RIDADR: UN 2811 6.1/PG 3
RTECS: UY9360000
HazardClass: IRRITANT