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38748-32-2

Basic Information
CAS No.: 38748-32-2
Name: Triptolide
Article Data: 9
Molecular Structure:
Molecular Structure of 38748-32-2 (Triptolide)
Formula: C20H24O6
Molecular Weight: 360.407
Synonyms: (-)-Triptolide;NSC 163062;PG 490;[3bS-(3ba,4aa,5aR*,6b,6ab,7ab,7ba,8aR*,8bb)]-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one;
EINECS: 300-006-3
Density: 1.48 g/cm3
Melting Point: 226-227 °C
Boiling Point: 601.7 °C at 760 mmHg
Flash Point: 220.7 °C
Solubility: soluble in DMSO
Appearance: White crystalline solid
Safety: 22-24/25
PSA: 84.12000
LogP: 1.10310
Downstream Products
195883-06-8
38647-11-9
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    Tel:15053231572

    Address:No.1581-12,Jinshui Road, Licang, Qingdao,China

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  • Triptolide

  • Casno:

    38748-32-2

    Triptolide

    Min.Order: 10 Milligram

    FOB Price:  USD $ 0.0-0.0

    Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine)

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  •  Hubei CuiRan Biotechnology Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:18162791556

    Address:Room 301, 3rd Floor, R&D Building, Private Science and Technology Park, Checheng South Road, Wuhan Economic and Technological Development Zone, Hubei Province

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  • TriptolidefromTripterygium wilfordii≥ 98% (HPLC)

  • Casno:

    38748-32-2

    TriptolidefromTripterygium wilfordii≥ 98% (HPLC)

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Why choice me: √1, We guarantee deeply analyze and demonstrate, purity more than 99% √ 2, Factory outlet with priority price & large stock. √ 3, Special magic vacuum safe package & safe shipping way.All parcel shipments

    Zibo Dorne chemical technology co., LTD. Is a comprehensive chemical enterprise integrating r&d, production and sales. It is a leading manufacturer and supplier of chemical product

  •  Zibo Dorne chemical technology co. LTD

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-13583358881

    Address:No. 416, 4th floor, zhongguancun science and technology city, no. 1, west 6th road, zhangdian district

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  • Thunder God Vine Extract Triptolide 98%

  • Casno:

    38748-32-2

    Thunder God Vine Extract Triptolide 98%

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

    Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, s

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    Business Type:Lab/Research institutions

    Tel:+86-15965530500

    Address:shandong

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  • Triptolide

  • Casno:

    38748-32-2

    Triptolide

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

    Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns

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     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:0731-85567275

    Address:No.10048, xiangjiang centry bulding ,kaifu district ,changsha city ,Hunan

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Chemistry

Name : Triptolide 

Molecular Structure :  

Molecular Formula : C20H24O6
Molecular Weight : 360.41
CAS Registry Number : 38748-32-2
storage temp : 2-8°C
form : solid
solubility :soluble
color :white to off-white
Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease Triptolide is a potent, biologically active compound isolated from the medicinal 'Thunder God Vine' Tripterygium wilfordii Hook F. The TCM tea Lei Gong Teng made from this plant has been used for centuries, as a therapeutic against cancer, inflammation, and auto-immune diseases. Crews and colleagues showed that triptolide causes cell growth arrest in certain cell types.

Uses

Diterpenoid triepoxide with immunosuppressant
antitumor properties

Toxicity Data With Reference

1.   

ipr-mus LD50:900 µg/kg

   CYLPDN    Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 2 (1981),70.
2.   

ivn-mus LD50:800 µg/kg

   CYLPDN    Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 2 (1981),70.
3.   

ivn-dog LDLo:160 µg/kg

   CYLPDN    Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 2 (1981),70.

Safety Profile

Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits acrid smoke and irritating fumes.