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3886-08-6

Basic Information
CAS No.: 3886-08-6
Name: N-Cbz-L-Glutamic acid 5-tert-butyl ester
Article Data: 6
Molecular Structure:
Molecular Structure of 3886-08-6 (N-Cbz-L-Glutamic acid 5-tert-butyl ester)
Formula: C17H23NO6
Molecular Weight: 337.373
Synonyms: (Benzyloxycarbonyl)-L-glutamic acid 5-tert-butyl ester;4(S)-Carboxy-4-(N-(benzyloxycarbonyl)amino)butanoic acid tert-butyl ester;Na-Benzyloxycarbonyl-g-tert-butyl-L-glutamic acid;(2S)-2-[[(Benzyloxy)carbonyl]amino]-5-tert-butoxy-5-oxopentanoicacid;Glutamicacid, N-carboxy-, N-benzyl 5-tert-butyl ester, L- (8CI);
EINECS: 223-421-3
Density: 1.197g/cm3
Melting Point: 83-87 °C
Boiling Point: 522.6 °C at 760 mmHg
Flash Point: 269.9 °C
Appearance: white to light yellow crystal powder
Hazard Symbols: Xi
Risk Codes: 36/37/38-43
Safety: 26-36/37
PSA: 101.93000
LogP: 2.87880
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Chemistry

IUPAC Name: 5-tert-Butyl N-((phenylmethoxy)carbonyl)-L-glutamate
The MF of 5-tert-Butyl N-((phenylmethoxy)carbonyl)-L-glutamate (3886-08-6) is C17H23NO6.

                            
The MW of 5-tert-Butyl N-((phenylmethoxy)carbonyl)-L-glutamate (3886-08-6) is 337.37.
Synonyms of 5-tert-Butyl N-((phenylmethoxy)carbonyl)-L-glutamate (3886-08-6): N-Cbz-L-Glutamic acid gamma-tert-butyl ester ; Z-Glu(OtBu)-OH 
Product Categories: chiral;Amino Acid Derivatives;PROTECTED AMINO ACID & PEPTIDES;Glutamic acid [Glu, E];Z-Amino Acids and Derivatives;Amino Acids;Amino Acids (N-Protected);Biochemistry;Cbz-Amino Acids;Z-Amino acid series
Form: white to light yellow crystal powder
Index of Refraction: 1.523  
EINECS: 223-421-3
Density: 1.197 g/ml
Flash Point: 271.5 °C
Boiling Point: 525.3 °C
Melting Point: 78-82 °C
Storage temp: -20 °C

Uses

    5-tert-Butyl N-((phenylmethoxy)carbonyl)-L-glutamate (3886-08-6) is monomer used for the protection of amino acids in peptide synthesis.

Production

With tert-butyl alcohol, and Cbz-L-glutamic acid esterification reaction.Products were purified by crystallization.

Safety Profile

Safety information of 5-tert-Butyl N-((phenylmethoxy)carbonyl)-L-glutamate (3886-08-6):
WGK Germany  3