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CAS No.: | 3978-86-7 |
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Name: | AZATADINE MALEATE (200 MG) |
Molecular Structure: | |
Formula: | C20H22N2.2(C4H4O4) |
Molecular Weight: | 522.60 |
Synonyms: | 6,11-dihydro-11-(1-methylpiperidin-4-ylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine dimaleate;6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine maleate (1:2);Optimine (TN);Azatadinum [INN-Latin];Azatadine maleate (USP);Azatadine maleate [USAN];Azatadina [INN-Spanish];5H-Benzo[5,6]cyclohepta[1,2-b]pyridine,6,11- dihydro-11-(1-methyl-4-piperidinylidene)-,(2Z)-2-butenedioate (1:2); |
EINECS: | 223-615-8 |
Melting Point: | 152-154° |
Boiling Point: | 450.1 °C at 760 mmHg |
Flash Point: | 226 °C |
Appearance: | Powder |
PSA: | 165.33000 |
LogP: | 3.06920 |
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Product Name: Azatadine maleate (200 mg)
Synonyms: 11H-benzo(5,6)cyclohepta(1,2-b)pyridine,5,6-dihydro-11-(1-methyl-4-piperidylid ; 6,11-Dihydro-11-(1-methyl-4-piperidylidene)5H-benzo(5,6)cyclohepta(1,2-b)pyr ; Azatadinedimaleate ; Azatadinemaleate ; Idinedimaleate ; Idulian ; Optimine ; SCH10649
CAS NO: 3978-86-7
Molecular Formula: C28H30N2O8
Molecular Weight: 522.5464
Molecular Structure:
EINECS: 223-615-8
Mol File: 3978-86-7.mol
Flash Point: 226 °C
Enthalpy of Vaporization: 70.89 kJ/mol
Boiling Point: 450.1 °C at 760 mmHg
Vapour Pressure: 2.71E-08 mmHg at 25°C
Appearance: 6,11-Dihydro-11-(1-methyl-4-piperidylidene)5H-benzo(5,6)cyclohepta(1,2-b)pyr (CAS NO. 3978-86-7) is white or beige powder, odorless.
1. 6,11-Dihydro-11-(1-methyl-4-piperidylidene)5H-benzo(5,6)cyclohepta(1,2-b)pyr (CAS NO. 3978-86-7) is anti-allergic drug .
2. 6,11-Dihydro-11-(1-methyl-4-piperidylidene)5H-benzo(5,6)cyclohepta(1,2-b)pyr (CAS NO. 3978-86-7) is release resistance agent of allergy media.
1. | orl-rat LD50:440 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),185. | ||
2. | ipr-rat LD50:166 mg/kg | JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 1 (1975),173. | ||
3. | scu-rat LD50:1000 mg/kg | JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 1 (1975),173. | ||
4. | orl-mus LD50:184 mg/kg | JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 1 (1975),173. | ||
5. | ipr-mus LD50:105 mg/kg | JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 1 (1975),173. | ||
6. | scu-mus LD50:178 mg/kg | JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 1 (1975),173. | ||
7. | scu-mus LDLo:50 mg/kg | JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 1 (1975),79. |
Poison by ingestion, subcutaneous, and intraperitoneal routes. An antihistamine. When heated to decomposition it emits toxic fumes of NOx.