Products Categories
CAS No.: | 407-97-6 |
---|---|
Name: | 1-Bromo-5-fluoropentane |
Article Data: | 3 |
Molecular Structure: | |
Formula: | C5H10BrF |
Molecular Weight: | 169.037 |
Synonyms: | 1-Bromo-5-fluoropentane;5-Fluoroamyl bromide; |
Density: | 1.303 g/cm3 |
Boiling Point: | 162 °C at 760 mmHg |
Flash Point: | 50.1 °C |
Solubility: | Soluble in methanol (in methanol). Slightly soluble in water. |
PSA: | 0.00000 |
LogP: | 2.52110 |
5-bromopentan-1-ol
1-bromo-5-fluoropentane
Conditions | Yield |
---|---|
With diethylamino-sulfur trifluoride In dichloromethane at -70 - 20℃; Inert atmosphere; | 61% |
Conditions | Yield |
---|---|
With potassium fluoride; diethylene glycol at 100℃; |
Conditions | Yield |
---|---|
Stage #1: indole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.166667h; Stage #2: 1-bromo-5-fluoropentane In N,N-dimethyl-formamide for 1h; Stage #3: trifluoroacetic anhydride In N,N-dimethyl-formamide for 1h; | 95% |
Stage #1: indole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.166667h; Inert atmosphere; Stage #2: 1-bromo-5-fluoropentane In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 1h; Inert atmosphere; Stage #3: trifluoroacetic anhydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 1h; Inert atmosphere; | |
Stage #1: indole With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 0.5h; Inert atmosphere; Stage #2: 1-bromo-5-fluoropentane In N,N-dimethyl-formamide at 0 - 20℃; for 1h; Inert atmosphere; Stage #3: trifluoroacetic anhydride In N,N-dimethyl-formamide at 0 - 20℃; for 2h; Inert atmosphere; |
Conditions | Yield |
---|---|
With 1,10-Phenanthroline; nickel(II) bromide diethylene glycol dimethyl ether; zinc In N,N-dimethyl-formamide at 60℃; for 10h; Inert atmosphere; Sealed tube; | 83% |
1-bromo-5-fluoropentane
1-(1,1,1-trifluoroprop-2-en-2-yl)-4-methoxybenzene
Conditions | Yield |
---|---|
With 3,4,7,8-Tetramethyl-o-phenanthrolin; (η(5)-indenyl)trichlorotitanium; nickel dibromide; zinc In N,N-dimethyl acetamide at 60℃; for 24h; Schlenk technique; Inert atmosphere; | 82% |
1-bromo-5-fluoropentane
tert-butylisonitrile
Conditions | Yield |
---|---|
With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); water; sodium t-butanolate In acetonitrile at 40℃; for 22h; Inert atmosphere; Sealed tube; | 78% |
1-bromo-5-fluoropentane
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 50℃; | 77% |
1-bromo-5-fluoropentane
N-[(1Z)-8-mercapto-5,6-dimethyl-3-oxo-2,3-dihydro-1H-imidazo[5,1-c][1,4]thiazin-1-ylidene]-4-methylbenzenesulfonamide
N-{(1Z)-8-[(5-fluoropentyl)thio]-5,6-dimethyl-3-oxo-2,3-dihydro-1H-imidazo[5,1-c][1,4]thiazin-1-ylidene}-4-methylbenzenesulfonamide
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide Heating; | 77% |
Conditions | Yield |
---|---|
With potassium carbonate In acetonitrile at 60℃; for 48h; | 76% |
Conditions | Yield |
---|---|
With methyllithium In tetrahydrofuran at 0 - 20℃; for 1.5h; Inert atmosphere; | 73% |
What can I do for you?
Get Best Price
The Pentane,1-bromo-5-fluoro- is an organic compound with the formula C5H10BrF. The IUPAC name of this chemical is 1-bromo-5-fluoropentane. With the CAS registry number 407-97-6, it is also named as 5-Fluoroamyl bromide.
Physical properties about Pentane,1-bromo-5-fluoro- are: (1)ACD/LogP: 2.50; (2)ACD/LogD (pH 5.5): 2.5; (3)ACD/LogD (pH 7.4): 2.5; (4)ACD/BCF (pH 5.5): 46.5; (5)ACD/BCF (pH 7.4): 46.5; (6)ACD/KOC (pH 5.5): 543.47; (7)ACD/KOC (pH 7.4): 543.47; (8)#Freely Rotating Bonds: 4; (9)Index of Refraction: 1.424; (10)Molar Refractivity: 33.1 cm3; (11)Molar Volume: 129.6 cm3; (12)Polarizability: 13.12×10-24cm3; (13)Surface Tension: 25.9 dyne/cm; (14)Density: 1.303 g/cm3; (15)Flash Point: 50.1 °C; (16)Enthalpy of Vaporization: 38.22 kJ/mol; (17)Boiling Point: 162 °C at 760 mmHg; (18)Vapour Pressure: 2.89 mmHg at 25°C.
You can still convert the following datas into molecular structure:
(1)SMILES: BrCCCCCF
(2)InChI: InChI=1/C5H10BrF/c6-4-2-1-3-5-7/h1-5H2
(3)InChIKey: GMYIZICPHREVDH-UHFFFAOYAM
(4)Std. InChI: InChI=1S/C5H10BrF/c6-4-2-1-3-5-7/h1-5H2
(5)Std. InChIKey: GMYIZICPHREVDH-UHFFFAOYSA-N
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 10480ug/kg (10.48mg/kg) | Canadian Journal of Biochemistry and Physiology. Vol. 36, Pg. 339, 1958. |