Welcome to LookChem.com Sign In|Join Free
  • or
Home > Pharmaceutical > 4472 > 

4472-02-0

Products Categories

Basic Information
CAS No.: 4472-02-0
Name: 3α-Acetyloxy-12-oxo-5β-chol-9(11)-en-24-oic acid methyl ester
Article Data: 21
Molecular Structure:
Molecular Structure of 4472-02-0 (3α-Acetyloxy-12-oxo-5β-chol-9(11)-en-24-oic acid methyl ester)
Formula: C27H40O5
Molecular Weight: 444.612
Synonyms: Methyl Ursodeoxycholate;methyl ester of ursodeoxycholic acid;Ursodeoxycholic Acid Methyl Ester;Methyl 3|A,7|A-Dihydroxy-5|A-cholanoate;
Density: 1.12g/cm3
Boiling Point: 531°Cat760mmHg
Flash Point: 224.6°C
PSA: 69.67000
LogP: 5.26540
Related products
Synthetic route
5143-55-5

methyl 3α-acetoxy-12-oxo-5β-cholan-24-oate

4472-02-0

methyl 3α-acetoxy-12-oxo-5β-chol-9(11)-en-24-oate

Conditions
ConditionsYield
With 3-iodosylbenzoic acid; diphenyl diselenide In toluene for 96h; Heating;89%
With selenium(IV) oxide; acetic acid for 18h; Reflux;78%
With selenium(IV) oxide; acetic acid
With selenium(IV) oxide; acetic acid at 180℃; for 0.5h; Temperature; Microwave irradiation;
30365-63-0

methyl 3α-acetoxy-5β-chol-9(11)-en-24-oate

A

1311972-67-4

C31H50O6

B

4472-02-0

methyl 3α-acetoxy-12-oxo-5β-chol-9(11)-en-24-oate

Conditions
ConditionsYield
Stage #1: methyl 3α-acetoxy-5β-chol-9(11)-en-24-oate With tert.-butylhydroperoxide; sodium hypochlorite In water; ethyl acetate at 0 - 5℃; for 7h;
Stage #2: With sodium sulfite In ethyl acetate
Stage #3: With pyridinium chlorochromate In ethyl acetate Product distribution / selectivity;		A n/a
B 63%
30365-63-0

methyl 3α-acetoxy-5β-chol-9(11)-en-24-oate

4472-02-0

methyl 3α-acetoxy-12-oxo-5β-chol-9(11)-en-24-oate

Conditions
ConditionsYield
Stage #1: methyl 3α-acetoxy-5β-chol-9(11)-en-24-oate With tert.-butylhydroperoxide; sodium hypochlorite In water; ethyl acetate at 0℃; for 8 - 10h;
Stage #2: With sodium sulfite In water; ethyl acetate at 50 - 55℃; for 2h;
Stage #3: With pyridinium chlorochromate In ethyl acetate at 25 - 30℃; for 6 - 8h; Product distribution / selectivity;		62%
Stage #1: methyl 3α-acetoxy-5β-chol-9(11)-en-24-oate With tert.-butylhydroperoxide; sodium hypochlorite In water; ethyl acetate at 0 - 5℃;
Stage #2: With pyridinium chlorochromate In ethyl acetate Solvent; Reagent/catalyst; Temperature;		60.6%
Multi-step reaction with 2 steps
1: tert.-butylhydroperoxide; sodium hypochlorite / ethyl acetate; water / 7 h / 0 - 5 °C
2: potassium carbonate; hydrogen / palladium on activated charcoal / dichloromethane / 24 h / 20 °C
View Scheme
Stage #1: methyl 3α-acetoxy-5β-chol-9(11)-en-24-oate With tert.-butylhydroperoxide; sodium hypochlorite In water; ethyl acetate at 0 - 5℃;
Stage #2: With pyridinium chlorochromate In ethyl acetate at 25 - 30℃; Reagent/catalyst; Solvent; Time; Temperature;		13 g
With chromium(VI) oxide In acetic acid at 50℃;
1311972-67-4

C31H50O6

4472-02-0

methyl 3α-acetoxy-12-oxo-5β-chol-9(11)-en-24-oate

Conditions
ConditionsYield
With tert.-butylhydroperoxide; palladium on activated charcoal; potassium carbonate In dichloromethane at 20℃; for 24h;11%
With hydrogen; potassium carbonate; palladium on activated charcoal In dichloromethane at 20℃; for 24h;11 %Chromat.
110-86-1

pyridine

88128-14-7

3α-acetoxy-11β-bromo-12-oxo-5β-cholan-24-oic acid methyl ester

4472-02-0

methyl 3α-acetoxy-12-oxo-5β-chol-9(11)-en-24-oate

108-75-8

2,4,6-trimethyl-pyridine

17550-22-0

3α-acetoxy-11α-bromo-12-oxo-5β-cholan-24-oic acid methyl ester

4472-02-0

methyl 3α-acetoxy-12-oxo-5β-chol-9(11)-en-24-oate

30365-63-0

methyl 3α-acetoxy-5β-chol-9(11)-en-24-oate

A

4472-02-0

methyl 3α-acetoxy-12-oxo-5β-chol-9(11)-en-24-oate

B

107329-63-5

3α-acetoxy-9,11β-epoxy-5β,9β-cholan-24-oic acid methyl ester

Conditions
ConditionsYield
With potassium permanganate; acetic acid
24637-48-7

12α-hydroxy-3α-acetoxy-5β-cholen-(9(11))-oic acid-(24)-methyl ester

4472-02-0

methyl 3α-acetoxy-12-oxo-5β-chol-9(11)-en-24-oate

Conditions
ConditionsYield
With chromium(VI) oxide; acetic acid
88128-14-7

3α-acetoxy-11β-bromo-12-oxo-5β-cholan-24-oic acid methyl ester

4472-02-0

methyl 3α-acetoxy-12-oxo-5β-chol-9(11)-en-24-oate

Conditions
ConditionsYield
With pyridine
65065-56-7

methyl 3α-hydroxy-12-oxo-5β-chol-9(11)-en-24-oate

108-24-7

acetic anhydride

4472-02-0

methyl 3α-acetoxy-12-oxo-5β-chol-9(11)-en-24-oate

Conditions
ConditionsYield
With pyridine
Hot Products
  • Display:default sort

    New supplier

  • 5.beta.-Chol-9 (11)-en-24-oic acid, 3.alpha.-hydroxy-12-oxo-, methyl ester, acetate

  • Casno:

    4472-02-0

    5.beta.-Chol-9 (11)-en-24-oic acid, 3.alpha.-hydroxy-12-oxo-, methyl ester, acetate

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 3.0-3.0

    DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

    Dayang Chem (Hangzhou) Co.,Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredi

  •  Dayang Chem (Hangzhou) Co.,Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-88938639

    Address:9/F, Unit 2 Changdi Torch Building, 259# WenSan Road, Xihu District, Hangzhou City 310012, P.R.China

       Inquiry Now

  • 5.beta.-Chol-9 (11)-en-24-oic acid, 3.alpha.-hydroxy-12-oxo-, methyl ester, acetate 4472-02-0

  • Casno:

    4472-02-0

    5.beta.-Chol-9 (11)-en-24-oic acid, 3.alpha.-hydroxy-12-oxo-, methyl ester, acetate 4472-02-0

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

    Shanghai Upbio Tech Co.,Ltd (Former Onchem (China)Co.,Ltd) is a comprehensive manufacturer and an international distribution of chemicals throughout the world, The predecessor of

  •  Shanghai Upbio Tech Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-52196435

    Address:No.2 Floor,No.979 Yunhan Rd,Nicheng,Pudong New Area,Shanghai,China

       Inquiry Now

  • 5.beta.-Chol-9 (11)-en-24-oic acid, 3.alpha.-hydroxy-12-oxo-, methyl ester, acetate

  • Casno:

    4472-02-0

    5.beta.-Chol-9 (11)-en-24-oic acid, 3.alpha.-hydroxy-12-oxo-, methyl ester, acetate

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

    The company is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds,

  •  Henan Wentao Chemical Product Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-370-2722992

    Address:32 Room, 5th Floor, Building 11, No. 6 Yinxing Road, High-tech Industrial Development Zone, Zhengzhou City, Henan Province

       Inquiry Now

  • 3|A,7|A-Dihydroxy-5|A-cholanic Acid Methyl Ester

  • Casno:

    4472-02-0

    3|A,7|A-Dihydroxy-5|A-cholanic Acid Methyl Ester

    Min.Order: 10 Gram

    FOB Price:  USD $ 100.0-100.0

    Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

    Hangyu Biotech is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and O

  •  Zibo Hangyu Biotechnology Development Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-15965530500

    Address:Room1701, Tianxing Building,Licheng district, jinan, Shandong, China

       Inquiry Now

  • 3|A,7|A-Dihydroxy-5|A-cholanic Acid Methyl Ester

  • Casno:

    4472-02-0

    3|A,7|A-Dihydroxy-5|A-cholanic Acid Methyl Ester

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

    Hangzhou Dingyan Chem Co., LTD. is located in the beautiful tourist city of hangzhou, is a comprehensive chemical enterprice which doing import and export business by its own comp

  •  Hangzhou Dingyan Chem Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:86-571-86465881,86-571-87157530,86-571-88025800

    Address:RM.1118,NO.1 Building, Baiyun Tower,Jianggan Area, Hangzhou city, China,310004

       Inquiry Now

  • 5.beta.-Chol-9 (11)-en-24-oic acid, 3.alpha.-hydroxy-12-oxo-, methyl ester, acetate

  • Casno:

    4472-02-0

    5.beta.-Chol-9 (11)-en-24-oic acid, 3.alpha.-hydroxy-12-oxo-, methyl ester, acetate

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

    Antimex Chemical Limied, was founded in 2001, we are specializing in manufacturing & researching of Active pharmaceutical Ingredients,Veterinary pharm APIs,cosmetic ingredients,and

  •  Antimex Chemical Limied

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:0086-21-50563169

    Address:Room1027,No.Jinyu Road,Pudong

       Inquiry Now

  • 3α-Acetyloxy-12-oxo-5β-chol-9(11)-en-24-oic acid methyl ester

  • Casno:

    4472-02-0

    3α-Acetyloxy-12-oxo-5β-chol-9(11)-en-24-oic acid methyl ester

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

    Henan Kanbei Chemical Co., Ltd. is a modern high-tech chemical enterprise integrating R&D, production and sales. The company has strong technical strength, advanced equipment, stri

  •  Henan Kanbei Chemical Co.,LTD

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-152-37804566

    Address:Evergrande Future City, intersection of Zhengkai Avenue and Sixteenth Street, Kaifeng Area, Henan Pilot Free Trade Zone

       Inquiry Now

  • 4472-02-0

  • Casno:

    4472-02-0

    4472-02-0

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

    Shanghai Chinqesen Biotechnology Co., Ltd. Company slogan:?Innovation, cooperation and win-win Company introduction:?Shanghai Chinqesen Biotechnology Co., Ltd. is a professional ph

  •  Shanghai Chinqesen Biotechnology Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8617316470195

    Address:333 Songze Avenue, Qingpu District, Shanghai

       Inquiry Now

  • 3|A,7|A-Dihydroxy-5|A-cholanic Acid Methyl Ester

  • Casno:

    4472-02-0

    3|A,7|A-Dihydroxy-5|A-cholanic Acid Methyl Ester

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Changzhou Extraordinary Pharmatech co., LTD. As a leading chemical manufacturer and supplier in China.DAS authentication is passed.We can provide the popular precursor chemicals, we have our own strong R & D team, have our own laboratories and fa

    Changzhou Extraordinary Pharmatech co., LTD. Is a full technical team and for the development of hardware and software facilities manufacturing enterprises,The company is located i

  • Changzhou Extraordinary Pharmatech co.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86 519 82111935

    Address:Chinese Jiangsu Province Changzhou City Jintan District Jincheng Town Miaotou NO4（Pharmaceutical Park）

       Inquiry Now

  • 5.beta.-Chol-9 (11)-en-24-oic acid, 3.alpha.-hydroxy-12-oxo-, methyl ester, acetate

  • Casno:

    4472-02-0

    5.beta.-Chol-9 (11)-en-24-oic acid, 3.alpha.-hydroxy-12-oxo-, methyl ester, acetate

    Min.Order: 1 Gram

    FOB Price:  USD $ 1.0-2.0

    HuBei ipure is a diversified product production and operation enterprise, with API, pharma intermediates, and other fine chemicals as well as R&D and pigments development and sales as one of the large enterprises, with more than 130 acres of plant

    Hubei Ipure biotech Co., Ltd. is Established in 2011,which is located in Wuhan, Hubei Province where is the largest city in central China. The company is a diversified product pr

  • HuBei Ipure Biotech CO.,ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:18062427325

    Address:NO 18. 81F street Future city ,Hongshan district ,WuHan city ,Hubei province ,China

       Inquiry Now

  • 5.beta.-Chol-9 (11)-en-24-oic acid, 3.alpha.-hydroxy-12-oxo-, methyl ester, acetate

  • Casno:

    4472-02-0

    5.beta.-Chol-9 (11)-en-24-oic acid, 3.alpha.-hydroxy-12-oxo-, methyl ester, acetate

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    5.beta.-Chol-9 (11)-en-24-oic acid, 3.alpha.-hydroxy-12-oxo-, methyl ester, acetateAppearance:Pls see the Details Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate T

    Nanjing Raymon Biotech Co., Ltd. is specialized in developing and marketing middle & high level pharmaceutical intermediates. We are supplying different categories of high-quality

  • Nanjing Raymon Biotech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-025-52181296

    Address:Block B, No. 918, Shuanglong Avenue

       Inquiry Now

  • 4472-02-0

  • Casno:

    4472-02-0

    4472-02-0

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Supply top quality products with a reasonable price Application:api

    Hebei Ruishun Trade Co.,Ltd registered capital one million, we have a production of pharmaceutical raw materials, pharmaceutical raw materials factory reagent r&d center, we do

  • Hebei Ruishun Trade Co.,Ltd

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-311-68037669

    Address:WanDa commerce building ,yuhua district

       Inquiry Now

  • Total:17 Page 1 of 1 1
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 4472-02-0