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460-35-5

Basic Information
CAS No.: 460-35-5
Name: 3-CHLORO-1,1,1-TRIFLUOROPROPANE
Article Data: 22
Molecular Structure:
Molecular Structure of 460-35-5 (3-CHLORO-1,1,1-TRIFLUOROPROPANE)
Formula: C3H4 Cl F3
Molecular Weight: 132.513
Synonyms: 1,1,1-Trifluoro-3-chloropropane;1-Chloro-3,3,3-trifluoropropane; 3,3,3-Trifluoro-1-chloropropane;3,3,3-Trifluorochloropropane; 3-Chloro-1,1,1-trifluoropropane; HCFC 253fb; R253fb
EINECS: 207-307-0
Density: 1.290
Melting Point: -106.2℃
Boiling Point: 44.1 °C at 760 mmHg
Flash Point: °C
Hazard Symbols:
Risk Codes: 22-36
Safety: A poison by ingestion. Moderately toxic by inhalation. When heated to decomposition it emits toxic fumes of F and Cl. See also CHLORINATED HYDROCARBONS, ALIPHATIC; and FLUORIDES.
PSA: 0.00000
LogP: 2.17760
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Chemistry

IUPAC Name: 3-Chloro-1,1,1-trifluoropropane
The MF of 3-Chloro-1,1,1-trifluoropropane (CAS NO.460-35-5) is C3H4ClF3.

                                  
The MW of 3-Chloro-1,1,1-trifluoropropane (CAS NO.460-35-5) is 132.51.
Synonyms of 3-Chloro-1,1,1-trifluoropropane (CAS NO.460-35-5): 1-Chloro-3,3,3-trifluoropropane ; Propane, 3-chloro-1,1,1-trifluoro- ; 1,1,1-Trifluoro-3-chloropropane
Product Categories: refrigerants;Fluorochemicals;API intermediates
Apperance: colorless odorless nonflammable liquid
Index of Refraction: 1.324  
EINECS: 207-307-0
Density: 1.252 g/ml 
Boiling Point: 44.1 °C

Uses

 3-Chloro-1,1,1-trifluoropropane (CAS NO.460-35-5) is used as chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.

Toxicity Data With Reference

1.    

ihl-rat LCLo:1800 mg/m3/2H

    85GMAT    Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow, USSR.: Centre of International Projects, GKNT,1982,115.
2.    

orl-mus LD50:62 mg/kg

    GISAAA    Gigiena i Sanitariya. 28 (12)(1963),9.
3.    

ihl-mus LC50:800 mg/m3/2H

    85GMAT    Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow, USSR.: Centre of International Projects, GKNT,1982,115.
4.    

ihl-rbt LCLo:2300 mg/m3/2H

    85GMAT    Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow, USSR.: Centre of International Projects, GKNT,1982,115.

Consensus Reports

Reported in EPA TSCA inventory.

Safety Profile

A poison by ingestion. Moderately toxic by inhalation. When heated to decomposition it emits toxic fumes of F and Cl. See also CHLORINATED HYDROCARBONS, ALIPHATIC; and FLUORIDES.Safety information of 3-Chloro-1,1,1-trifluoropropane (CAS NO.460-35-5):
Hazard Codes  IrritantXi
Safety Statements 
23 Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer)
24/25 Avoid contact with skin and eyes
Hazard Note  Irritant

Specification

It is chemically inert in many situations, but can react violently with strong reducing agents such as the very active metals and the active metals. Undergoes oxidation with strong oxidizing agents and under extremes of temperature.Poisonous by inhalation. Emits toxic fumes of chlorine and fluorine when heated to decomposition.