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484-23-1

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Basic Information
CAS No.: 484-23-1
Name: Ophthazin
Article Data: 14
Molecular Structure:
Molecular Structure of 484-23-1 (Ophthazin)
Formula: C8H10 N6
Molecular Weight: 190.208
Synonyms: 1,4-Phthalazinedione,2,3-dihydro-, dihydrazone (9CI); Phthalazine, 1,4-dihydrazino- (7CI,8CI);1,4-Dihydrazinophthalazine; C 7441; Cassella 532; Dihydralazin; Dihydralazine;Dihydrazinophthalazine; Hypopresol; NSC 526654; Nepresol; Nepresolin;Nepressol; Ophthazin; Tonolysin
EINECS: 207-605-0
Density: 1.543 g/cm3
Melting Point: 180ºC
Boiling Point: 648.3 °C at 760 mmHg
Flash Point: 345.9 °C
Safety: Poison by intravenous route. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx.
PSA: 108.34000
LogP: 0.44540
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  • Dihydralazine

  • Casno:

    484-23-1

    Dihydralazine

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  • Ophthazin

  • Casno:

    484-23-1

    Ophthazin

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  • Ophthazin

  • Casno:

    484-23-1

    Ophthazin

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  • 1,4-Dihydrazino-phthalazine

  • Casno:

    484-23-1

    1,4-Dihydrazino-phthalazine

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Chemistry

MF: C8H10N6
MW: 190.21
EINECS: 207-605-0
Density: 1.543 g/cm3
Flash Point: 345.9 °C 
Index of Refraction: 1.899 
Appearance: Orange needle crystal
Enthalpy of Vaporization: 95.58 kJ/mol 
Boiling Point: 648.3 °C at 760 mmHg 
Vapour Pressure: 1.09E-16 mmHg at 25°C
IUPAC Name: (4-Hydrazinylphthalazin-1-yl)hydrazine
Solubility Ophthazin (484-23-1): Slightly soluble in water, soluble in water or ethanol
Synonyms: 1,4-Dihydrazinonaphthalazine ; 1,4-Dihydrazino-phthalazin ; 2,3-Dihydro-1,4-phthalazinedionedihydrazone ; 4-Phthalazinedione,2,3-dihydro-Dihydrazone ; C7441 ; Cassella532 ; Dihydralazin
Following is the molecular structure of Ophthazin (484-23-1):

Uses

Ophthazin (484-23-1) for blood. Direct effect on peripheral vascular, reduce blood pressure especially suitable for renal insufficiency, and diastolic blood pressure patients with high, rarely orthostatic hypotension. Also can be used as high-molecular compounds containing carbonyl of chain, complexing agent and applied in analytical chemistry.

Toxicity Data With Reference

1.    

ivn-mus LD50:300 mg/kg

     EJMCA5    European Journal of Medicinal Chemistry. Chimie Therapeutique. 11 (1976),107.

Safety Profile

Poison by intravenous route. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx.