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Basic Information
CAS No.: 49557-75-7
Name: Glycyl-L-Histidyl-L-Lysine
Molecular Structure:
Molecular Structure of 49557-75-7 (Glycyl-L-Histidyl-L-Lysine)
Formula: C14H24N6O4
Molecular Weight: 340.382
Synonyms: L-Lysine,N2-(N-glycyl-L-histidyl)-;Glycyl-L-histidyl-L-lysine;Growth-modulating peptide (human);Liver cell growthfactor;Liver growth factor;NSC 379527;
EINECS: 1592732-453-0
Density: 1.324 g/cm3
Boiling Point: 831 °C at 760 mmHg
Flash Point: 456.4 °C
Appearance: White powder
PSA: 176.22000
LogP: 0.27650
Synthetic route
29022-11-5

N-(fluoren-9-ylmethoxycarbonyl)glycine

71989-26-9

Fmoc-Lys(tert-butoxycarbonyl)

109425-51-6

Fmoc-His(Trt)-OH

49557-75-7

glycyl-L-histidyl-L-lysine

Conditions
ConditionsYield
Multistep reaction;40%
64516-48-9

malondialdehyde

75-07-0

acetaldehyde

49557-75-7

glycyl-L-histidyl-L-lysine

(S)-6-Amino-2-[(S)-2-[2-(3,5-diformyl-4-methyl-4H-pyridin-1-yl)-acetylamino]-3-(1H-imidazol-4-yl)-propionylamino]-hexanoic acid

Conditions
ConditionsYield
In water at pH 4.2;
120550-35-8

biotin pentafluorophenyl ester

49557-75-7

glycyl-L-histidyl-L-lysine

C24H38N8O6S

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 20℃; for 5h;
PEG succinimidyl propionate derivative

PEG succinimidyl propionate derivative

49557-75-7

glycyl-L-histidyl-L-lysine

PEG-glycyl-L-histidyl-L-lysine

PEG-glycyl-L-histidyl-L-lysine

Conditions
ConditionsYield
at 20℃;
at 20℃;

potassium tetrachloropalladate(II)

49557-75-7

glycyl-L-histidyl-L-lysine

[(NH2(CH2CO)NCH(CONHCH(COO)CH2CH2CH2CH2NH3)CH2(CCHNHCHN))PdCl]

Conditions
ConditionsYield
In water acidic soln.;; monitored by (1)H/(13)C-NMR spectroscopy;;
In water-d2 acidic soln.;; monitored by (1)H/(13)C-NMR spectroscopy;;
142-71-2

copper diacetate

49557-75-7

glycyl-L-histidyl-L-lysine

copper tripeptide-1

Conditions
ConditionsYield
With sodium methylate In methanol; water at 20℃; for 2h;
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    Copper peptide GHK-Cu CAS:49557-75-7 Specification Test Items Standard Results Appearance Blue powder Blue powder Identit

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  • L-Lysine,glycyl-L-histidyl-

  • Casno:

    49557-75-7

    L-Lysine,glycyl-L-histidyl-

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  • Copper Peptide 99% Pure High Quality Anti-Aging /Anti-Wriklepeptide Peptide

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    49557-75-7

    Copper Peptide 99% Pure High Quality Anti-Aging /Anti-Wriklepeptide Peptide

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    Hubei Mawer Biological Technology Co., Ltd is a leading manufacturer and supplier of API,Steroids,Peptide,HGH, Pharma intermediates, organic and inorganic compounds, rare earth, pe

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  • Copper Peptide

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    49557-75-7

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  • Glycyl-L-Histidyl-L-Lysine

  • Casno:

    49557-75-7

    Glycyl-L-Histidyl-L-Lysine

    Min.Order: 100 Gram

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  • GHK-GHK-Cu cas no.49557-75-7 0.98

  • Casno:

    49557-75-7

    GHK-GHK-Cu cas no.49557-75-7 0.98

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    Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

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Specification

The L-Lysine,glycyl-L-histidyl-, with the CAS registry number 49557-75-7, has the systematic name of glycyl-L-histidyl-L-lysine.
 
The physical properties of this chemical are as follows: (1)ACD/LogP: -2.24; (2)# of Rule of 5 Violations: 2; (3)ACD/LogD (pH 5.5): -6.61; (4)ACD/LogD (pH 7.4): -5.23; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 10; (10)#H bond donors: 8; (11)#Freely Rotating Bonds: 13; (12)Polar Surface Area: 91.22 ; (13)Index of Refraction: 1.582; (14)Molar Refractivity: 85.82 cm3; (15)Molar Volume: 256.9 cm3; (16)Polarizability: 34.02×10-24 cm3; (17)Surface Tension: 67.4 dyne/cm; (18)Density: 1.324 g/cm3; (19)Flash Point: 456.4 °C; (20)Enthalpy of Vaporization: 126.59 kJ/mol; (21)Boiling Point: 831 °C at 760 mmHg; (22)Vapour Pressure: 2.86E-29 mmHg at 25°C.

Additionally, you could obtain the molecular structure by converting the following datas:
(1)SMILES:O=C(O)[C@@H](NC(=O)[C@@H](NC(=O)CN)Cc1cncn1)CCCCN
(2)InChI:InChI=1/C14H24N6O4/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9/h7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24)/t10-,11-/m0/s1
(3)InChIKey:MVORZMQFXBLMHM-QWRGUYRKBM