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| CAS No.: | 514-61-4 |
|---|---|
| Name: | Normethisterone |
| Molecular Structure: | |
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|
|
| Formula: | C19H28O2 |
| Molecular Weight: | 288.43 |
| Synonyms: | Estr-4-en-3-one,17b-hydroxy-17-methyl- (8CI);17-Methyl-19-nortestosterone;17a-Methyl-17b-hydroxy-4-estrene-3-one;17a-Methyl-19-nortestosterone;17a-Methyl-3-oxo-4-estren-17b-ol;17a-Methylestra-4-en-17-ol-3-one;17b-Hydroxy-17a-methylestr-4-en-3-one;19-Normethisterone;Lutenin;Methylnortestosterone;NSC 10039;Normetandrone;Orgasteron;RU 598; |
| EINECS: | 208-183-0 |
| Density: | 1.12 g/cm3 |
| Melting Point: | 153-158 °C |
| Boiling Point: | 434.6 °C at 760 mmHg |
| Flash Point: | 185.4 °C |
| Appearance: | white solid |
| Risk Codes: | R20/21; R65 |
| PSA: | 37.30000 |
| LogP: | 3.87920 |
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
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- 68439-39-4Poly(oxy-1,2-ethanediyl), alpha-(2-ethylhexyl)-omega-hydroxy-,
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- 2863-88-9
3-ethoxy-19-nor-3,5-androstadiene-17-one
- 75-16-1
methylmagnesium bromide
- 514-61-4
normethandrolone
| Conditions | Yield |
|---|---|
| With hydrogenchloride |
- 75-16-1
methylmagnesium bromide
- 96111-40-9
3,3-ethanediyldioxy-17ξ-hydroxy-estr-5-ene-17ξ-carbonitrile
- 514-61-4
normethandrolone
| Conditions | Yield |
|---|---|
| With hydrogenchloride |
| Conditions | Yield |
|---|---|
| With acetic acid |
- 514-61-4
normethandrolone
| Conditions | Yield |
|---|---|
| With hydrogenchloride; ammonia; lithium |
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: CrO3 3: aqueous HCl View Scheme |
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 2: aqueous HCl View Scheme |
- 514-61-4
normethandrolone
A
- 1428370-33-5
17α-methyl-6β,17β-dihydroxyestr-4-en-3-one
B
- 1428370-34-6
17α-(hydroxymethyl)-11β,17β-dihydroxyestr-4-en-3-one
C
- 1428370-35-7
17α-methyl-2α,11β,17β-trihydroxyestr-4-en-3-one
D
- 1428370-36-8
17α-methyl-1β,17β-dihydroxyestr-4-en-3-one
E
- 7100-20-1
17α-methyl-11β,17β-dihydroxyestr-4-en-3-one
F
- 7100-20-1
17α-methyl-11α,17β-dihydroxyestr-4-en-3-one
| Conditions | Yield |
|---|---|
| With Macrophomina phaseolina KUCC 730 In water for 192h; Microbiological reaction; | A 0.018% B 0.008% C 0.006% D 0.045% E 0.014% F 0.0045% |
- 514-61-4
normethandrolone
A
- 1428370-37-9
17α-methyl-3,17β-dihydroxyestr-1,3,5(10)-trien-6-one
B
- 302-76-1
17-methyl-estra-1,3,5(10)-triene-3,17α-diol
C
- 7100-20-1
17α-methyl-11β,17β-dihydroxyestr-4-en-3-one
| Conditions | Yield |
|---|---|
| With Gibberella fujikuroi ATCC 10704 In water; acetone for 264h; Microbiological reaction; | A 0.01% B 0.014% C n/a |
- 514-61-4
normethandrolone
A
- 1428370-33-5
17α-methyl-6β,17β-dihydroxyestr-4-en-3-one
B
- 18318-25-7
17α-methyl-10β,17β-dihydroxyestr-4-en-3-one
C
- 67473-37-4
17α-(hydroxymethyl)-17β-hydroxyestr-4-en-3-one
| Conditions | Yield |
|---|---|
| With Aspergillus niger ATCC 10549 In water; acetone for 336h; Microbiological reaction; | A n/a B 0.008% C 0.012% |
- 514-61-4
normethandrolone
A
- 1428370-38-0
17α-methyl-6β,10β,17β-trihydroxyestr-4-en-3-one
B
- 7100-20-1
17α-methyl-11α,17β-dihydroxyestr-4-en-3-one
| Conditions | Yield |
|---|---|
| With Cunninghamella echinulata ATCC 9244 In water; acetone for 288h; Microbiological reaction; | A 0.006% B n/a |
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Chemistry
Product Name: Metalutin (CAS NO.514-61-4)
Molecular Formula: C19H28O2
Molecular Weight: 288.42g/mol
Mol File: 514-61-4.mol
Einecs: 208-183-0
Melting Point: 153-158°C
Boiling point: 434.6 °C at 760 mmHg
Flash Point: 185.4 °C
Density: 1.12 g/cm3
Surface Tension: 44.4 dyne/cm
Enthalpy of Vaporization: 79.75 kJ/mol
Vapour Pressure: 2.22E-09 mmHg at 25°C
XLogP3-AA: 2.8
H-Bond Donor: 1
H-Bond Acceptor: 2
Toxicity Data With Reference
| 1. | orl-wmn TDLo:18 mg/kg (12-24W preg):TER | BRGOAY Bulletin de la Societa Royale Belge de Gynecologie et dObstetrique. 28 (1958),137. | ||
| 2. | orl-rbt TDLo:200 µg/kg (female 1D pre):REP | 85GRAA The Control of Fertility Pincus, G.,New York, NY.: Academic Press,1965,57. |
Safety Profile
Human teratogenic effects by ingestion: extra embryonic structures and developmental abnormalities of the urogenital system. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes. See also TESTOSTERONE.
Specification
Metalutin ,its CAS NO. is 514-61-4,the synonyms is Normethandrolone ; Normethandrone ; Normethisterone ; Norethandrone ; 17-Alpha-methyl-17-beta-hydroxy-4-estren-3-one ; 17-Beta-hydroxy-17-alpha-methyl-estr-4-en-3-on ; 17-Beta-hydroxy-17-methylestr-4-en-3-one ; 17-Methyl-19-nortestosterone .