CAS No.51627-14-6,Cefatrizine Suppliers

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Basic Information

Molecular Structure:
CAS No.:	51627-14-6
Name:	Cefatrizine

Formula:	C₁₈H₁₈N₆O₅S₂
Molecular Weight:	538.59 .
Synonyms:	5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-amino(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(1H-1,2,3-triazol-4-ylthio)methyl]-,(6R,7R)- (9CI);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[amino(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(1H-1,2,3-triazol-4-ylthio)methyl]-,[6R-[6a,7b(R*)]]-;7-[D-a-Amino-a-(4-hydroxyphenyl)acetamido]-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylicacid;Antibiotic BL-S 640;BL-S 640;Cefaperos;Cefatrizine;Cephatrizin;Cepticol;S 640P;SKF 60771;
EINECS:	257-324-2
Density:	1.73 g/cm³
Boiling Point:	948.1 °C at 760 mmHg
Flash Point:	527.2 °C
Appearance:	White to slightly yellowish powder
PSA:	225.13000
LogP:	1.07010

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Chemistry

Chemical Name: Cefatrizine
IUPAC NAME: (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-
8-oxo-3-(2H-triazol-4-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-
2-ene-2-carboxylic acid
CAS No.: 51627-14-6
EINECS: 257-324-2
Molecular Formula: C₁₈H₁₈N₆O₅S₂
Molecular Weight: 538.6 g/mol
Density: 1.73 g/cm³
Flash Point: 527.2 °C
Boiling Point: 948.1 °C at 760 mmHg
Following is the structure of ANTIBIOTIC BL-640 (51627-14-6):

The chemical synonymous of ANTIBIOTIC BL-640 (51627-14-6) are CEFATRIZINE ; CEFATRIZINE PROPYLENE GLYCOL ; 7-[2-(4-hydroxyphenyl)-2-aminoacetamido]-3-(1,2,3-triazole-4-ylthio)methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ; antibioticbl-640 ; antibioticbl-s640 ; bls640 ; cephatriazine ; eta(r)))-

Uses

ANTIBIOTIC BL-640 (51627-14-6) is primarily used to treat liver and gallbladder infections caused by susceptible strains, urinary tract infections, respiratory infections, septicemia, endocarditis and meningitis and other illnesses.

Toxicity Data With Reference

1.	orl-rat TDLo:175 mg/kg (8-14D preg):REP	JJANAX Japanese Journal of Antibiotics. 29 (1976),129.
2.	orl-rat TDLo:5600 mg/kg (female 8-14D post):TER	JJANAX Japanese Journal of Antibiotics. 29 (1976),129.
3.	orl-rat LD:>6 g/kg	JJANAX Japanese Journal of Antibiotics. 29 (1976),612.
4.	ipr-rat LD50:4325 mg/kg	JJANAX Japanese Journal of Antibiotics. 29 (1976),612.
5.	ipr-mus LD50:6410 mg/kg	JJANAX Japanese Journal of Antibiotics. 29 (1976),612.
6.	ipr-rbt LD50:1500 mg/kg	JJANAX Japanese Journal of Antibiotics. 29 (1976),612.
7.	scu-rbt LD50:3000 mg/kg	JJANAX Japanese Journal of Antibiotics. 29 (1976),612.

Safety Profile

Moderately toxic by intraperitoneal and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very highly toxic fumes of NO_x and SO_x.