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CAS No.: | 51781-06-7 |
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Name: | 5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydro-1H-quinolin-2-one |
Article Data: | 9 |
Molecular Structure: | |
Formula: | C16H24 N2 O3 |
Molecular Weight: | 292.378 |
Synonyms: | (?à)-Carteolol; Carteolol;dl-Carteolol |
Density: | 1.13 g/cm3 |
Boiling Point: | 518.6 °C at 760 mmHg |
Flash Point: | 267.4 °C |
Safety: | Poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. |
PSA: | 70.59000 |
LogP: | 2.22800 |
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Chemistry informtion about Carteolol (CAS NO.51781-06-7) is:
IUPAC Name: 5-[3-(Tert-Butylamino)-2-Hydroxypropoxy]-3,4-Dihydro-1h-Quinolin-2-One
Synonyms: 2(1h)-Quinolinone, 5-[3-[(1,1-Dimethylethyl)Amino]-2-Hydroxypropoxy]-3,4-Dihydro- ; Carteolol ; 2(H)-Quinolinone, 5-[3-[(1,1-Dimethylethyl)Amino]-2-Hydroxypropoxy]-3,4-Dihydro- ; Dl-Carteolol ; Carteolol (Base And/Or Unspecified Salts) ; 5-[3-(Tert-Butylamino)-2-Hydroxypropoxy]-3,4-Dihydro-1h-Quinolin-2-One ; 5-(2-Hydroxy-3-Tert-Butylaminopropoxy)-3,4-Dihydro-2(1h)-Quinolone ; 5-[3-(Tert-Butylamino)-2-Hydroxypropoxy]-3,4-Dihydrocarbostyril
MF: C16H24N2O3
MW: 292.37
Density: 1.13 g/cm3
Flash Point: 267.4 °C
Boiling Point: 518.6 °C at 760 mmHg
Vapour Pressure: 1.4E-11 mmHg at 25°C
Enthalpy of Vaporization: 83.29 kJ/mol
Following is the molecular structure of Carteolol (CAS NO.51781-06-7) is:
Carteolol (CAS NO.51781-06-7) is a non-selective beta blocker used to treat glaucoma.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | oral | 830mg/kg (830mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980. | |
mouse | LD50 | oral | 810mg/kg (810mg/kg) | Japanese Journal of Toxicology. Vol. 4, Pg. 121, 1991. | |
rabbit | LD50 | intravenous | 112mg/kg (112mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980. | |
rabbit | LD50 | oral | 740mg/kg (740mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980. |
Poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.