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CAS No.: | 5189-11-7 |
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Name: | Pizotifen Malate |
Molecular Structure: | |
Formula: | C19H21NS |
Molecular Weight: | 429.53 |
Synonyms: | Butanedioicacid, hydroxy-, compd. with4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine(1:1) (9CI);Malic acid, compd. with 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine(1:1) (8CI);Malic acid, compd. with4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine(7CI);4H-Benzo[4,5]cyclohepta[1,2-b]thiophene, 9,10-dihydro-4-(1-methyl-4-piperidylidene)-,malate (1:1) (8CI);4H-Benzo[4,5]cyclohepta[1,2-b]thiophene, piperidine deriv.;Piperidine,4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methyl-,hydroxybutanedioate (1:1) (9CI);Piperidine, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methyl-,malate (1:1) (8CI);4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidiniumhydrogen malate;Mosegor;Pizotifen hydrogen malate;Pizotifen malate;Pizotyline malate;Sanmigran;Sanomigran; |
EINECS: | 225-970-4 |
Density: | 1.164 g/cm3 |
Melting Point: | 185-186° (dec) |
Boiling Point: | 436.7 °C at 760 mmHg |
Flash Point: | 217.9 °C |
Hazard Symbols: | Xi |
Risk Codes: | 36/37/38 |
Safety: | 26-37/39 |
PSA: | 106.08000 |
LogP: | 4.02390 |
Product Name: Pizotyline malate (CAS NO.5189-11-7)
Molecular Formula: C23H27NO5S
Molecular Weight: 429.53g/mol
Mol File: 5189-11-7.mol
Einecs: 225-970-4
Boiling point: 436.7 °C at 760 mmHg
Flash Point: 217.9 °C
Enthalpy of Vaporization: 69.32 kJ/mol
Vapour Pressure: 7.92E-08 mmHg at 25
H-Bond Donor: 3
H-Bond Acceptor: 6
InChI: InChI=1S/C19H21NS.C4H6O5/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-
18-17(19)10-13-21-18;5-2(4(8)9)1-3(6)7/h2-5,10,13H,6-9,11-12H2,1H3;2,5H,
1H2,(H,6,7)(H,8,9)
InChIKey: IWAWCPZVTXCFKD-UHFFFAOYSA-N
Product Categories: Active Pharmaceutical Ingredients
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intravenous | 43mg/kg (43mg/kg) | Japanese Journal of Pharmacology. Vol. 19, Pg. 19, 1969. | |
rabbit | LD50 | intravenous | 19mg/kg (19mg/kg) | Japanese Journal of Pharmacology. Vol. 19, Pg. 19, 1969. | |
rat | LD50 | intravenous | 17mg/kg (17mg/kg) | Japanese Journal of Pharmacology. Vol. 19, Pg. 19, 1969. | |
women | TDLo | oral | 600ug/kg (0.6mg/kg) | SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP | Postgraduate Medical Journal. Vol. 63, Pg. 59, 1987. |
Safety Information of Pizotyline malate (CAS NO.5189-11-7):
Hazard Codes: Xi
Risk Statements: 36/37/38
36: Irritating to the eyes
37: Irritating to the respiratory system
38: Irritating to the skin
Safety Statements: 26-37/39
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
37: Wear suitable gloves
39: Wear eye/face protection
Pizotyline malate ,its CAS NO. is 5189-11-7,the synonyms is Litec malate ; Mosegor ; Pizotifen hydrogen malate ; Pizotifen malate ; Sandomigran malate ; Sandomygran malate ; Sanomtgran ; Malic acid, compound with 4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methylpiperidine (1:1) ; Piperidine, 4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methyl-, malate (1:1) .