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52092-47-4

Basic Information
CAS No.: 52092-47-4
Name: 5-Chloro-2-nitropyridine
Article Data: 11
Molecular Structure:
Molecular Structure of 52092-47-4 (5-Chloro-2-nitropyridine)
Formula: C5H3ClN2O2
Molecular Weight: 158.544
Synonyms: 2-Nitro-5-chloropyridine;NSC 90388;
Density: 1.489 g/cm3
Melting Point: 119-123oC
Boiling Point: 275.3 °C at 760 mmHg
Flash Point: 120.3 °C
Hazard Symbols: IrritantXi
Risk Codes: 20/21/22-36/37/38
Safety: 26-36/37/39-36
PSA: 58.71000
LogP: 2.16640
Synthetic route
1072-98-6

5-chloro-2-pyridylamine

52092-47-4

5-chloro-2-nitropyridine

Conditions
ConditionsYield
With sulfuric acid; dihydrogen peroxide at 20℃; for 48h;71%
With caro's acid
Multi-step reaction with 2 steps
1: 94 percent / trifluoroacetic anhydride / CH2Cl2 / -60 °C
2: 62 percent / trifluoroacetic acid, H2O2 / CH2Cl2 / 1.5 h / 0 °C
View Scheme
134251-85-7

2-dimethylsulfilimino-5-chloropyridine

A

52092-47-4

5-chloro-2-nitropyridine

B

134251-87-9

5-Chloro-2-nitro-pyridine 1-oxide

Conditions
ConditionsYield
With dihydrogen peroxide; trifluoroacetic acid In dichloromethane at 0℃; for 1.5h;A 62%
B 38%
99848-04-1

(3-chloro-6-nitro-[2]pyridyl)-hydrazine

52092-47-4

5-chloro-2-nitropyridine

Conditions
ConditionsYield
With water; silver(I) acetate
15128-82-2

3-hydroxy-2-nitropyridine

52092-47-4

5-chloro-2-nitropyridine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: acetic acid anhydride; nitric acid
2: phosphorus (V)-chloride / 130 °C
3: methanol; N2H4
4: silver acetate; water
View Scheme
Multi-step reaction with 4 steps
1: acetic acid; acetic acid anhydride; nitric acid
2: phosphorus (V)-chloride / 130 °C
3: methanol; N2H4
4: silver acetate; water
View Scheme
15128-91-3

3-hydroxy-2,6-dinitropyridine

52092-47-4

5-chloro-2-nitropyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: phosphorus (V)-chloride / 130 °C
2: methanol; N2H4
3: silver acetate; water
View Scheme
101079-67-8

3-chloro-2,6-dinitro-pyridine

52092-47-4

5-chloro-2-nitropyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: methanol; N2H4
2: silver acetate; water
View Scheme
1072-98-6

5-chloro-2-pyridylamine

concentrated H2 SO4

concentrated H2 SO4

7722-84-1

dihydrogen peroxide

52092-47-4

5-chloro-2-nitropyridine

Conditions
ConditionsYield
In ethyl acetate; toluene
67-56-1

methanol

52092-47-4

5-chloro-2-nitropyridine

124-41-4

sodium methylate

126739-64-8

3-methoxy-6-nitropyridine

Conditions
ConditionsYield
at 20℃;100%
52092-47-4

5-chloro-2-nitropyridine

106-44-5

p-cresol

2-nitro-5-(p-tolyloxy)pyridine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 12h;94%
110-85-0

piperazine

52092-47-4

5-chloro-2-nitropyridine

775288-71-6

1-(6-nitropyridin-3-yl)piperazine

Conditions
ConditionsYield
In butan-1-ol at 22 - 100℃;89.5%
In isopropyl alcohol at 80 - 85℃; for 24h; Time;102.2 g
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    5-Chloro-2-nitropyridine Chemical Properties Melting point 119-123℃ Boiling point 275.3±20.0 °C(Predicted) density 1.489±0.06 g/cm3(Predicted) pka -4.87±0.22(Predicted) CAS DataBase Reference 52092-47-4(CAS

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Chemistry

Molecular Structure of 5-Chloro-2-nitropyridine(52092-47-4)

IUPAC Name:5-chloro-2-nitropyridine
Molecular Formula:C5H3ClN2O2
Molecular Weight:158.542520 g/mol
Density:1.489 g/cm3
Flash Point:120.3 °C
Enthalpy of Vaporization:49.3 kJ/mol
Boiling Point:275.3 °C at 760 mmHg
Vapour Pressure:0.00865 mmHg at 25 °C
Water Solubility:2345 mg/L at 25 °C
Synonyms of 5-Chloro-2-nitropyridine(52092-47-4):
5-CHLORO-2-NITROPYRIDINE;3-Chloro-6-nitropyridine;5-CHLORO-2-NITROPYRIDINE/2-NITRO-5-CHLOROPYRIDINE
Categories of 5-Chloro-2-nitropyridine(52092-47-4):
Pyridine;Pyridines

Safety Profile

Safety Information of 5-Chloro-2-nitropyridine(52092-47-4):
Hazard Codes:Xi
Risk Statements:20/21/22-36/37/38
20/21/22:Harmful by inhalation, in contact with skin and if swallowed
36/37/38:Irritating to eyes, respiratory system and skin
Safety Statements:26-36/37/39-36
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39:Wear suitable protective clothing, gloves and eye/face protection
36:Wear suitable protective clothing
Hazard Note:Irritant
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