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| CAS No.: | 524-42-5 |
|---|---|
| Name: | 1,2-NAPHTHOQUINONE |
| Article Data: | 113 |
| Molecular Structure: | |
|
|
|
| Formula: | C10H6O2 |
| Molecular Weight: | 158.156 |
| Synonyms: | NSC 9831;SID 8139964;o-Naphthoquinone; |
| EINECS: | 208-360-2 |
| Density: | 1.29 g/cm3 |
| Melting Point: | 139-142 °C (dec.)(lit.) |
| Boiling Point: | 296.068 °C at 760 mmHg |
| Flash Point: | 117.376 °C |
| Appearance: | brown powder |
| Hazard Symbols: |
 Xn, Xi, C, F
|
| Risk Codes: | 22-36/37/38-34-11 |
| Safety: | 26-36-45-36/37/39-16 |
| PSA: | 34.14000 |
| LogP: | 1.46520 |
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Chemistry
Chemical Name: 1,2-Naphthoquinone
IUPAC NAME: Naphthalene-1,2-dione
CAS No.: 524-42-5
EINECS: 208-360-2
RTECS: QL7000000
Molecular Formula: C10H6O2
Molecular Weight: 158.15 g/mol
Melting Point: 139-142 °C (dec.)(lit.)
Density: 1.29 g/cm3
Flash Point: 117.4 °C
Boiling Point: 296.1 °C at 760 mmHg
Storage temp.: 2-8°C
Following is the structure of 1,2-Naphthoquinone (CAS No.524-42-5):
Product Categories about 1,2-Naphthoquinone (CAS No.524-42-5) are Intermediates of Dyes and Pigments ; Anthraquinones, Hydroquinones and Quinones
The chemical synonymous of 1,2-Naphthoquinone (CAS No.524-42-5) are 1,2-Dihydro-1,2-Diketo-Naphthalene ; 1,2-Naftochinon ; 1,2-Naphthaquinone ; O-Naphthoquinone ; Naphthoquinone, 1,2- ; Beta-Naphthoquinone ; 1,2-Naphthalenedione ; 1,2-Naphthoquinone
Toxicity Data With Reference
| 1. | orl-rat LDLo:250 mg/kg | NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. 5 (1953),39. | ||
| 2. | orl-mus LDLo:1070 mg/kg | AECTCV Archives of Environmental Contamination and Toxicology. 14 (1985),111. | ||
| 3. | orl-bwd LD50:75 mg/kg | AECTCV Archives of Environmental Contamination and Toxicology. 12 (1983),355. |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
Poison by ingestion. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Note: Irritant
Hazard Codes: 
Xn 
F 
Xi 
C
Risk Statements about 1,2-Naphthoquinone (CAS No.524-42-5):
R11:Highly flammable.
R22:Harmful if swallowed.
R34:Causes burns.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements about 1,2-Naphthoquinone (CAS No.524-42-5):
S16:Keep away from sources of ignition.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Attention:
1. Storage: Store in a cool, dry place. Store in a tightly closed container
2. Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Specification
1,2-Naphthoquinone (CAS No.524-42-5) is a polycyclic aromatic ketone. It is a reactive metabolite of naphthalene. This compound is a quinone found in diesel exhaust particles. The accumulation of this toxic metabolite in rats from doses of naphthalene has been shown to cause eye damage, including the formation of cataracts.