Products Categories
| CAS No.: | 52415-29-9 |
|---|---|
| Name: | 6-Bromo-1H-indole |
| Article Data: | 36 |
| Molecular Structure: | |
|
|
|
| Formula: | C8H6BrN |
| Molecular Weight: | 196.046 |
| Synonyms: | 1H-Indole, 6-bromo-;6-bromo-1H-indole;Bromoindole; |
| EINECS: | -0 |
| Density: | 1.66 g/cm3 |
| Melting Point: | 92-96 °C(lit.) |
| Boiling Point: | 316.9 °C at 760 mmHg |
| Flash Point: | 145.5 °C |
| Appearance: | white to brown powder |
| Hazard Symbols: |
 Xi
|
| Risk Codes: | 36/37/38 |
| Safety: | 26-36-37/39 |
| PSA: | 15.79000 |
| LogP: | 2.93040 |
- 81281-59-67-Benzylideneaminotheophylline
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 68439-39-4Poly(oxy-1,2-ethanediyl), alpha-(2-ethylhexyl)-omega-hydroxy-,
- 852475-26-4MC1568
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 717878-06-31-(4-fluorophenyl)-4-nitro-1H-imidazole
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 548773-13-32-amino-4,6-dimethylpyrimidine-5-carboxylic acid
- 16732-65-3
6-bromo-indole-2-carboxylic acid(Ref.7.)
- 52415-29-9
6-bromo-1H-indole
| Conditions | Yield |
|---|---|
| With quinoline; copper Heating; | 98% |
| With copper In quinoline Heating; | 95% |
| With quinoline; copper(I) bromide |
- 99474-21-2
(E)-2-(4-bromo-2-nitrophenyl)-N,N-dimethylethyleneamine
- 52415-29-9
6-bromo-1H-indole
| Conditions | Yield |
|---|---|
| With iron(III) chloride hexahydrate; pyrographite; hydrazine hydrate In ethanol at 75℃; for 7h; | 93% |
| With zinc In acetic acid at 85℃; for 2h; | 62% |
| With acetic acid; zinc In methanol; dichloromethane Heating; | 52% |
| With acetic acid; zinc at 75 - 85℃; for 3.5h; | 2.675 g |
- 60956-26-5
4-bromo-2-nitrotoluene
- 4637-24-5
N,N-dimethyl-formamide dimethyl acetal
- 52415-29-9
6-bromo-1H-indole
| Conditions | Yield |
|---|---|
| Stage #1: 4-bromo-2-nitrotoluene; N,N-dimethyl-formamide dimethyl acetal With pyrrolidine In N,N-dimethyl-formamide at 110℃; for 2h; Stage #2: With hydrogenchloride; titanium(III) chloride; ammonium acetate In N,N-dimethyl-formamide at 0℃; for 0.25h; | 90% |
| Stage #1: 4-bromo-2-nitrotoluene; N,N-dimethyl-formamide dimethyl acetal With pyrrolidine In 1,4-dioxane at 102℃; for 3.5h; Leimgruber-Batcho Indole Synthesis; Reflux; Inert atmosphere; Stage #2: With hydrazine hydrate In 1,4-dioxane at 45℃; for 1h; Leimgruber-Batcho Indole Synthesis; | 82% |
| Stage #1: 4-bromo-2-nitrotoluene; N,N-dimethyl-formamide dimethyl acetal With pyrrolidine In N,N-dimethyl-formamide at 105 - 110℃; for 21h; Leimgruber-Batcho Indole Synthesis; Stage #2: With acetic acid; zinc at 70 - 90℃; for 3h; Temperature; Reagent/catalyst; Leimgruber-Batcho Indole Synthesis; | 56% |
- 99365-40-9
6-bromo-2,3-dihydro-1H-indole-2-one
- 52415-29-9
6-bromo-1H-indole
| Conditions | Yield |
|---|---|
| With bis(trimethylsilyl)amide yttrium(III); 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane In toluene at 120℃; for 36h; Inert atmosphere; | 90% |
- 189265-99-4
6-bromo-1-(4-methylphenylsulfonyl)-1H-indole
- 52415-29-9
6-bromo-1H-indole
| Conditions | Yield |
|---|---|
| With sodium hydride In N,N-dimethyl acetamide at 60℃; for 5h; Inert atmosphere; | 85% |
- 496-15-1
1-indoline
- 52415-29-9
6-bromo-1H-indole
| Conditions | Yield |
|---|---|
| Stage #1: 1-indoline With silver(II) sulfate; sulfuric acid for 0.5h; Stage #2: With bromine for 0.5h; Stage #3: With chloranil In 5,5-dimethyl-1,3-cyclohexadiene for 5h; Reflux; | 73% |
- 52448-17-6
(2S)-2-amino-3-(6-bromo-1H-indol-3-yl)propanoic acid
- 52415-29-9
6-bromo-1H-indole
| Conditions | Yield |
|---|---|
| With dipotassium hydrogenphosphate; tryptophanase TnaA at 25℃; pH=7.4; Enzymatic reaction; | 70.4% |
- 52415-29-9
6-bromo-1H-indole
| Conditions | Yield |
|---|---|
| With ammonium hydroxide; iron(II) sulfate Heating; | 31% |
- 78508-22-2
β-dimethylamino-2-nitrostyrene
- 52415-29-9
6-bromo-1H-indole
| Conditions | Yield |
|---|---|
| With acetic acid; zinc In water at 75℃; for 1h; Stirred; | 27% |
| With hydrogen; W-2 Raney nickel In ethanol | 340 mg |
| With acetic acid; zinc | |
| With hydrogen In benzene under 2585.81 Torr; for 26h; | 0.29 g |
- 123-75-1
pyrrolidine
- 60956-26-5
4-bromo-2-nitrotoluene
- 4637-24-5
N,N-dimethyl-formamide dimethyl acetal
- 52415-29-9
6-bromo-1H-indole
| Conditions | Yield |
|---|---|
| With ammonium acetate; titanium(III) chloride 1) DMF, 100-110 deg C, 2 h, 2) water, DMF; Yield given. Multistep reaction; | |
| With zinc In hexane; acetic acid; N,N-dimethyl-formamide | |
| With zinc In hexane; acetic acid; N,N-dimethyl-formamide | |
| With zinc In hexane; acetic acid; N,N-dimethyl-formamide |
What can I do for you?
Get Best Price
Chemistry
Molecule structure of 6-Bromoindole (CAS NO.52415-29-9):
IUPAC Name: 6-Bromo-1H-indole
Molecular Weight: 196.04394 g/mol
Molecular Formula: C8H6BrN
Density: 1.66 g/cm3
Melting Point: 92-96 °C(lit.)
Boiling Point: 316.9 °C at 760 mmHg
Flash Point: 145.5 °C
Index of Refraction: 1.711
Molar Refractivity: 46.21 cm3
Molar Volume: 118 cm3
Polarizability: 18.32×10-24 cm3
Surface Tension: 54.8 dyne/cm
Enthalpy of Vaporization: 53.61 kJ/mol
Vapour Pressure: 0.000738 mmHg at 25 °C
XLogP3: 3.3
H-Bond Donor :1
Exact Mass: 194.968362
MonoIsotopic Mass: 194.968362
Topological Polar Surface Area: 15.8
Heavy Atom Count: 10
Canonical SMILES: C1=CC(=CC2=C1C=CN2)Br
InChI: InChI=1S/C8H6BrN/c9-7-2-1-6-3-4-10-8(6)5-7/h1-5,10H
InChIKey: MAWGHOPSCKCTPA-UHFFFAOYSA-N
Product Categories: blocks; Bromides; IndolesOxindoles; Indole/indoline/oxindole; Indoles and derivatives; pharmacetical; Indole; Indoles; Heterocyclic Compounds; Halogenated; Organohalides; Simple Indoles; Halogenated Heterocycles; Heterocyclic Building Blocks; IndolesBuilding Blocks
Safety Profile
Hazard Codes: 
Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany: 3
Hazard Note: Irritant
HazardClass: IRRITANT
Specification
6-Bromoindole (CAS NO.52415-29-9) is also named as 1H-indole, 6-bromo- ; 6-Brom-1H-indol ; 6-Bromo-1H-indole . 6-Bromoindole (CAS NO.52415-29-9) is white to brown powder.