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| CAS No.: | 53-41-8 |
|---|---|
| Name: | Androsterone |
| Article Data: | 109 |
| Molecular Structure: | |
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|
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| Formula: | C19H30O2 |
| Molecular Weight: | 290.446 |
| Synonyms: | 3-Epihydroxyetioallocholan-17-one;3a-Hydroxy-17-androstanone;3a-Hydroxy-5a-androstan-17-one;3a-Hydroxy-5a-androstane-17-one;5a-Androstan-17-one-3a-ol;5a-Androstane-3a-ol-17-one;5a-Androsterone;Androkinin;Androtin;Atromide ICI;NSC9898;U 60366; |
| EINECS: | 200-173-4 |
| Density: | 1.085 g/cm3 |
| Melting Point: | 181-184 °C(lit.) |
| Boiling Point: | 413.139 °C at 760 mmHg |
| Flash Point: | 176.377 °C |
| Solubility: | 11.5mg/L(23.5 oC) |
| Appearance: | white to light beige crystalline powder |
| Hazard Symbols: | Xi |
| Risk Codes: | 36/37/38-43 |
| Safety: | 22-24/25 |
| PSA: | 37.30000 |
| LogP: | 3.95910 |
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- 111222-34-5
(3R,5S,8R,9S,10S,13S,14S)-10,13-Dimethyl-3-(tetrahydro-furan-2-yloxy)-hexadecahydro-cyclopenta[a]phenanthren-17-one
- 53-41-8
cis-androsterone
| Conditions | Yield |
|---|---|
| With toluene-4-sulfonic acid In ethanol for 1h; Ambient temperature; | 100% |
| Conditions | Yield |
|---|---|
| With methanol; sodium hydroxide at 40℃; for 4h; Inert atmosphere; | 94.6% |
| With potassium carbonate |
| Conditions | Yield |
|---|---|
| With Oxone; edetate disodium; sodium hydrogencarbonate In water; acetonitrile at 20℃; for 120h; | A 20% B 78% |
| Conditions | Yield |
|---|---|
| With sodium methylate In methanol; dichloromethane at 20℃; | 75% |
| Conditions | Yield |
|---|---|
| With trimethylamine-borane; silica gel; iron(III) chloride In benzene for 2h; Ambient temperature; | A 60.2% B 20.9% |
| With trimethylamine-borane; silica gel; iron(III) chloride In benzene for 2h; Product distribution; Ambient temperature; various catalysts and times; | A 60.2% B 20.9% |
| With hydrogen; Nic In tetrahydrofuran; ethanol at 25℃; under 760 Torr; for 1.16667h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; |
- 5717-77-1, 15807-49-5, 35420-27-0, 57194-49-7
(3α,5α)-3-hydroxyandrostan-17-one 1,2-ethanediyl acetal
- 53-41-8
cis-androsterone
| Conditions | Yield |
|---|---|
| With methanesulfonic acid In methanol; water for 0.25h; | 57% |
| With acetic acid |
- 592509-66-5
2-Oxo-heptanoic acid (3R,5S,8R,9S,10S,13S,14S)-10,13-dimethyl-17-oxo-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester
A
- 53-41-8
cis-androsterone
| Conditions | Yield |
|---|---|
| With Oxone; edetate disodium; sodium hydrogencarbonate In water; acetonitrile at 20℃; for 72h; | A 45% B 55% |
| Conditions | Yield |
|---|---|
| With HEK-293 cells expressing Haliotis diversicolor supertexta 17β-hydroxysteroid dehydrogenase 11; fetal bovine serum In dimethyl sulfoxide for 23h; aq. buffer; Enzymatic reaction; | 53.4% |
| With rabbit 3-hydroxyhexobarbital dehydrogenase (AKR1C29); NADP In aq. phosphate buffer; ethyl acetate at 37℃; for 0.5h; pH=7.4; Catalytic behavior; Kinetics; Enzymatic reaction; | |
| With recombinant male golden hamster liver aldo-keto reductase AKR1C35; NAD In aq. phosphate buffer at 25℃; pH=7.4; Kinetics; Enzymatic reaction; |
- 10429-07-9
3β-tosyloxy-5α-androstan-17-one
A
- 53-41-8
cis-androsterone
B
- 846-46-8
androstanedione
C
- 14639-79-3, 24174-20-7, 82467-84-3, 963-75-7
5α-androst-2-en-17-one
| Conditions | Yield |
|---|---|
| With potassium nitrite In N,N-dimethyl-formamide at 80 - 85℃; for 18h; | A 51.5% B 0.03 g C 0.01 g |
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Chemistry
Chemical Formula: C19H30O2 
Molecular Weight: 290.44
Synonyms: 3-hydroxy-,(3alpha,5alpha)-androstan-17-on ; 5alpha-Androstan-17-one, 3alpha-hydroxy- ; 3-alpha-hydroxy-17-androstanone ; 3-Epihydroxyetioallocholan-17-one ; 5alpha-Androstane-3alpha-ol-17-one
Melting Point: 181-184 °C(lit.)
Flash Point: 176.4 °C
Boiling Point: 413.1 °C at 760 mmHg
Density of Androsterone (53-41-8) : 1.085 g/cm3
Vapour Pressure: 1.5E-08 mmHg at 25°C
alpha of Androsterone (53-41-8) : 96°(c=1, C2H5OH)
storage temp.: -20°C
Index of Refraction: 1.536
Chemical Properties: Androsterone (53-41-8) is a white to light beige crystalline powder
Safety Profile
An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.
Safety Statements: 22: Do not breathe dust
24/25: Avoid contact with skin and eyes
WGK Germany: 3
RTECS: BV8053000
F: 3: Hygroscopic
21: Sensitive to humidity
StorageKeep container tightly closed. Keep container in a cool, well-ventilated area.
Specification
Storage: Keep container in a cool, well-ventilated area. Keep container tightly closed.