CAS No.5308-25-8,1-Ethylpiperazine Suppliers

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Basic Information

Molecular Structure:
CAS No.:	5308-25-8
Name:	1-Ethylpiperazine
Article Data:	37

Formula:	C₆H₁₄ N₂
Molecular Weight:	114.191
Synonyms:	N-Ethylpiperazin;N-Ethylpiperazine;NSC 60707;
EINECS:	226-166-6
Density:	0.895 g/cm³
Melting Point:	-60 °C
Boiling Point:	156 °C at 760 mmHg
Flash Point:	53 °C
Solubility:	soluble in water
Appearance:	clear colorless to yellow liquid
Hazard Symbols:	Xi
Risk Codes:	36/37/38
Safety:	26-36
Transport Information:	UN 1993 3/PG 3
PSA:	15.27000
LogP:	0.17820

Synthetic route

: C11H22N2O2

: 5308-25-8
4-ethylpiperazine

Conditions

Conditions	Yield
With trifluoroacetic acid at 20℃; for 0.0833333h;	94%

: 110-85-0
piperazine

: 75-00-3
chloroethane

A: 5308-25-8
4-ethylpiperazine

B: 6483-50-7
1,4-diethylpiperazine

Conditions

Conditions	Yield
	A 20% B 55%

...Expand

: 21863-75-2
4-ethyl-1-formylpiperazine

: 5308-25-8
4-ethylpiperazine

Conditions

Conditions	Yield
With hydrogenchloride

: 74-96-4
ethyl bromide

: 7542-23-6
piperazine hydrochloride

: 5308-25-8
4-ethylpiperazine

Conditions

Conditions	Yield
With ethanol

: 98951-41-8
4-ethyl-piperazine-1-carboxylic acid ethyl ester

: 5308-25-8
4-ethylpiperazine

Conditions

Conditions	Yield
With hydrogen bromide; acetic acid
With hydrogenchloride

: 24426-42-4
EtN(CH2CN)2

: 5308-25-8
4-ethylpiperazine

Conditions

Conditions	Yield
With nickel; platinum; benzene at 44℃; Hydrogenation;

: 557-66-4
ethanamine hydrochloride

: 10024-89-2
morpholin hydrochloride

: 5308-25-8
4-ethylpiperazine

Conditions

Conditions	Yield
at 265℃;
at 265℃;

: 660-68-4
diethyl amine hydrochloride

: 10024-89-2
morpholin hydrochloride

: 5308-25-8
4-ethylpiperazine

Conditions

Conditions	Yield
at 250℃;

: 1-benzyl-4-ethylpiperazine dihydrochloride

: 5308-25-8
4-ethylpiperazine

Conditions

Conditions	Yield
With palladium on activated charcoal Hydrogenation;

: 821-48-7
bis-(2-chloroethyl)amine hydrochloride

: 75-04-7
ethylamine

: 5308-25-8
4-ethylpiperazine

Conditions

Conditions	Yield
at 130℃;

Raw Materials

75-00-3

110-85-0

75-04-7

10024-89-2

821-48-7

7542-23-6

74-96-4

557-66-4

Downstream Products

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Chemistry

IUPAC Name:1-ethylpiperazine
Molecular Formula:C₆H₁₄N₂
Molecular Weight:114.188760 g/mol
Appearance:clear, colorless liquid
Melting Point:-60 °C
Boiling Point:157 °C(lit.)
Flash Point:110 °F
density:0.899 g/mL at 25 °C(lit.)
refractive index:n20/D 1.469(lit.)
storage temp.:flammables area
Water Solubility:soluble
Sensitive:Air
BRN:102971
EINECS:226-166-6
Synonyms of N-ethyl Piperazine(5308-25-8):
1-ethyl-piperazin;Piperazine, 1-ethyl-;ETHYLPIPERAZINE-N;LABOTEST-BB LTBB000704;1-ETHYLPIPERAZINE;AKOS BBS-00003610;N-ETHYLPIPERAZINE;NEPRZ;1-Ethylpiperazine
Categories of N-ethyl Piperazine(5308-25-8):
Piperidines,Piperidones,Piperazines;Piperaizine;Piperazines;Building Blocks;Heterocyclic Building Blocks

Uses

N-ethyl Piperazine(5308-25-8) is used as an intermediate for veterinary medicine mainly used in the production of ciproflmoxacin ethyl.
N-ethyl Piperazine(5308-25-8) is also used as a raw material for the production of dyes and plant protection agents.

Toxicity Data With Reference

Toxicity Information of N-ethyl Piperazine(5308-25-8):
1.rat LC50 inhalation > 9219mg/m3/4H (9219mg/m3)
SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION International Journal of Toxicology. Vol. 16
2.rat LD50 oral 2158mg/kg (2158mg/kg)
LUNGS, THORAX, OR RESPIRATION: PULMONARY EMBOLI
GASTROINTESTINAL: NAUSEA OR VOMITING
GASTROINTESTINAL: OTHER CHANGES
International Journal of Toxicology. Vol. 16

Safety Profile

Safety Information of N-ethyl Piperazine(5308-25-8):
Hazard Codes:Xi
Risk Statements:36/37/38
36/37/38:Irritating to eyes, respiratory system and skin
Safety Statements:26-36
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:Wear suitable protective clothing
RIDADR:UN 1993 3/PG 3
WGK Germany:1
RTECS:TM0815500
F:10-34
HazardClass:3
PackingGroup:III
HS Code:29335995

Specification

First Aid Measures of N-ethyl Piperazine(5308-25-8):
Ingestion:Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:Get medical aid immediately. Remove from exposure to fresh air immediately. Do not use mouth-to-mouth respiration if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Skin:Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Eyes:Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).