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5371-52-8

Basic Information
CAS No.: 5371-52-8
Name: 2-HYDROXYTETRAHYDROFURAN
Article Data: 96
Molecular Structure:
Molecular Structure of 5371-52-8 (2-HYDROXYTETRAHYDROFURAN)
Formula: C4H8O2
Molecular Weight: 88.1063
Synonyms: Tetrahydro-2-furanol;oxolan-2-ol;2-Hydroxytetrahydrofuran;
Density: 1.148g/cm3
Boiling Point: 163.6°Cat760mmHg
Flash Point: 75.1°C
PSA: 29.46000
LogP: 0.11520
Synthetic route
Ph3 P

Ph3 P

5129-72-6

N-ethylpropionamide

5371-52-8

2-hydroxytetrahydrofuran

Conditions
ConditionsYield
HRh(CO)(PPh3)3 In para-xylene93%
5129-72-6

N-ethylpropionamide

5371-52-8

2-hydroxytetrahydrofuran

Conditions
ConditionsYield
With triphenylphosphine; HRh(CO)(PPh3)3 In para-xylene93%
96-48-0

4-butanolide

5371-52-8

2-hydroxytetrahydrofuran

Conditions
ConditionsYield
With diisobutylaluminium hydride In toluene at -78℃; for 1h; Reduction;79%
With diisobutylaluminium hydride In diethyl ether; hexane at -78℃; for 3h;64%
With diisobutylaluminium hydride In toluene at -78℃; for 3h;52%
1191-99-7

2,3-dihydro-2H-furan

5371-52-8

2-hydroxytetrahydrofuran

Conditions
ConditionsYield
With dihydrogen peroxide at 45℃; for 24h;76%
With hydrogenchloride at 0 - 20℃;67%
With hydrogenchloride; water at 0℃; for 0.5h;61%
6117-80-2

1,4-butenediol

A

5371-52-8

2-hydroxytetrahydrofuran

B

25714-71-0

4-hydroxybutyraldehyde

Conditions
ConditionsYield
With hydrogen; montmorillonite-diphenylphosphinepalladium(II) under 760 Torr; for 30h; Ambient temperature;A 72%
B n/a
109-99-9

tetrahydrofuran

5371-52-8

2-hydroxytetrahydrofuran

Conditions
ConditionsYield
With C36H40Cu2N6O2(2+) In acetone at -70℃;62%
With tert.-butylhydroperoxide; copper(l) chloride
With 3,3-dimethyldioxirane In acetone at 25℃; Kinetics;96 % Chromat.
With [{Cu(II)(Me2NMePY2)}2(O2)](B(C6H5)4)2 In dichloromethane at -80℃; Product distribution; Kinetics; Further Variations:; Reagents; other substrates;
1191-99-7

2,3-dihydro-2H-furan

A

5371-52-8

2-hydroxytetrahydrofuran

B

110-63-4

Butane-1,4-diol

Conditions
ConditionsYield
With hydrogen In 1,4-dioxane; water at 139.84℃; under 60006 Torr; for 4h;A 5%
B 52%
109-99-9

tetrahydrofuran

4676-82-8

2-hydroperoxytetrahydrofuran

107-13-1

acrylonitrile

A

5371-52-8

2-hydroxytetrahydrofuran

B

16237-62-0

2-(β-cyanoethyl)tetrahydrofuran

C

3-[2-(2-Cyano-ethyl)-tetrahydro-furan-2-yl]-propionitrile

D

2-(Tetrahydro-furan-2-ylmethyl)-pentanedinitrile

E

3-[5-(2-Cyano-ethyl)-tetrahydro-furan-2-yl]-propionitrile

Conditions
ConditionsYield
at 130℃; for 4h; Product distribution; Mechanism; He-atmosphere, other temperatures, times and initiators;A n/a
B 49%
C n/a
D n/a
E n/a
1191-99-7

2,3-dihydro-2H-furan

A

5371-52-8

2-hydroxytetrahydrofuran

B

453-20-3

3-Hydroxytetrahydrofuran

C

71780-57-9

tetrahydrofuran-2'-yl ether

Conditions
ConditionsYield
With water; hydrogen In 1,4-dioxane at 139.84℃; under 60006 Torr; for 4h;A 18%
B 8%
C 46%
With water; hydrogen; pyrographite In 1,4-dioxane at 139.84℃; under 60006 Torr; for 4h;A 18%
B 8%
C 46%
109-99-9

tetrahydrofuran

A

5371-52-8

2-hydroxytetrahydrofuran

B

96-48-0

4-butanolide

Conditions
ConditionsYield
With cobalt(III) acetylacetonate; oxygen In ethyl acetate at 70℃; for 24h; Product distribution; various cyclic ethers;A 9%
B 30%
With tert.-butylhydroperoxide; water; copper(II) bis(trifluoromethanesulfonate) at 90℃; for 20h; Inert atmosphere;A 21%
B 7%
With dihydrogen peroxide In water at 66℃; for 4h; Temperature; Green chemistry;A 6.85%
B 16.65%
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  • 2-Furanol, tetrahydro-

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Chemistry

IUPAC Name: Oxolan-2-ol
Synonyms of 2-Furanol, tetrahydro- (CAS NO.5371-52-8): Tetrahydro-2-furanol
CAS NO: 5371-52-8
Molecular Formula of 2-Furanol, tetrahydro- (CAS NO.5371-52-8): C4H8O2
Molecular Weight: 88.1051
Molecular Structure:

ProductCategories: Miscellaneous Reagents 
Polar Surface Area: 18.46 Å2
Index of Refraction: 1.475
Molar Refractivity: 21.64 cm3
Molar Volume: 76.7 cm3
Surface Tension: 38.7 dyne/cm
Density of 2-Furanol, tetrahydro- (CAS NO.5371-52-8): 1.148 g/cm3
Flash Point: 75.1 °C
Enthalpy of Vaporization: 46.6 kJ/mol
Boiling Point: 163.6 °C at 760 mmHg
Vapour Pressure: 0.697 mmHg at 25°C