Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products > 538 > 

538-71-6

Products Categories

Basic Information
CAS No.: 538-71-6
Name: 1-Dodecanaminium,N,N-dimethyl-N-(2-phenoxyethyl)-, bromide (1:1)
Molecular Structure:
Molecular Structure of 538-71-6 (1-Dodecanaminium,N,N-dimethyl-N-(2-phenoxyethyl)-, bromide (1:1))
Formula: C22H40NO.Br
Molecular Weight: 414.54
Synonyms: 1-Dodecanaminium,N,N-dimethyl-N-(2-phenoxyethyl)-, bromide (9CI);Ammonium, dodecyldimethyl(2-phenoxyethyl)-,bromide (8CI);Dodecyldimethyl(2-phenoxyethyl)ammonium bromide (6CI,7CI);(b-Phenoxyethyl)dimethyldodecylammoniumbromide;Bradonit;Bradoral;Bradosol;Bradosol bromide;Domiphen bromide;Fungitex;Fungitex R;Modicare;N-Dodecyl-N-(2-phenoxyethyl)dimethylammoniumbromide;NSC 39415;Neo-Bradoral;Oradol;PDDB;Phenododecinium bromide;
EINECS: 208-702-0
Density: 1.1411 (rough estimate)
Melting Point: 117-119 °C(lit.)
Boiling Point:
Flash Point:
Solubility: Soluble in ethanol, acetone, ethyl acetate, chloroform and water. Slightly soluble in benzene.
Appearance:
Hazard Symbols: IrritantXi
Risk Codes: 36/37/38
Safety: 26-36
Transport Information: UN 2811 6.1/PG 3
PSA: 9.23000
LogP: 3.06670
Synthetic route
13468-02-5

dimethyl(2-phenoxyethyl)amine

143-15-7

1-dodecylbromide

538-71-6

domiphen brominde

124-22-1

n-Dodecylamine

589-10-6

phenoxyethyl bromide

538-71-6

domiphen brominde

Conditions
ConditionsYield
With methyl bromide; formaldehyd; formic acid
112-18-5

N,N-dimethylaminododecane

589-10-6

phenoxyethyl bromide

538-71-6

domiphen brominde

Conditions
ConditionsYield
With ethyl acetate
With acetone
With water
538-71-6

domiphen brominde

1918-00-9

3,6-dichloro-2-methoxybenzoate sodium salt

dodecyldimethylphenoxyethylammonium 3,6-dichloro-2-methoxybenzoate

Conditions
ConditionsYield
In water99.5%
16484-77-8

(R)-Mecoprop

538-71-6

domiphen brominde

1354725-99-7

domiphen (+)-(R)-2-(4-chloro-2-methylphenoxy)propionate

Conditions
ConditionsYield
Stage #1: (R)-Mecoprop With potassium hydroxide In water at 39.84℃;
Stage #2: domiphen brominde In water for 24h;
99%
538-71-6

domiphen brominde

1082249-07-7

domiphen (4-chloro-2-methylphenoxy)acetate

Conditions
ConditionsYield
With sodium hydroxide In water for 2h;98%
538-71-6

domiphen brominde

147-85-3

L-proline

C22H40NO(1+)*C5H8NO2(1-)

Conditions
ConditionsYield
With potassium hydroxide In water at 59.84℃; for 12h;92%
1071-83-6

N-(phosphonemethyl)glycine

538-71-6

domiphen brominde

bis(N,N-dimethyl-N-dodecyl-N-phenoxyethylammonium) glyphosate

Conditions
ConditionsYield
Stage #1: domiphen brominde With potassium hydroxide In 1,4-dioxane at 25℃; for 6h;
Stage #2: N-(phosphonemethyl)glycine In 1,4-dioxane at 25℃; for 6h;
92%
  • Display:default sort

    New supplier

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemistry

1.IUPAC Name:  Dodecyl-dimethyl-(2-phenoxyethyl)azanium bromide
2.Synonyms: Domiphen bromide ; Oradol ; Bradasol ; Bradonit ; Bradoral ; Fungitex ; Bradosol bromide ; Fungitex R ; Phenododecinium bromide ; Oradol (TN) ; Domipheni bromidum [INN-Latin] ; HSDB 7236 ; 247480_ALDRICH ; Bromure de domiphene [INN-French] ; Bromuro de domifeno
3.The Molecular Formula of  Dodecyldimethyl(2-phenoxyethyl)ammonium bromide (538-71-6) :C22H40BrNO
4.The Molecular Weight of  Dodecyldimethyl(2-phenoxyethyl)ammonium bromide (538-71-6) : 414.46g/mol
5.The Molecular Structure of   Dodecyldimethyl(2-phenoxyethyl)ammonium bromide (538-71-6): 
6.Melting Point:117-119 °C(lit.)
7.Topological Polar Surface Area: 9.2

Uses

1.   Dodecyldimethyl(2-phenoxyethyl)ammonium bromide (538-71-6)  is used widely in the ENT.  
2. This item can be used as antiseptic and active pharmaceutical ingredient.

Toxicity Data With Reference

1.    

add-bac-esc 10 µmol/L

    MUREAV    Mutation Research. 89 (1981),95.
2.    

ipr-rat LD50:40 mg/kg

    FEPRA7    Federation Proceedings, Federation of American Societies for Experimental Biology. 6 (1947),307.
3.    

ivn-rat LD50:18 mg/kg

    FEPRA7    Federation Proceedings, Federation of American Societies for Experimental Biology. 6 (1947),307.
4.    

ivn-mus LD50:31 mg/kg

    FEPRA7    Federation Proceedings, Federation of American Societies for Experimental Biology. 6 (1947),307.
5.    

ivn-rbt LDLo:11 mg/kg

    FEPRA7    Federation Proceedings, Federation of American Societies for Experimental Biology. 6 (1947),307.
6.    

ipr-gpg LDLo:10 mg/kg

    HBTXAC    Handbook of Toxicology, Volumes I-V. 1 (1956),222.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Poison by intraperitoneal and intravenous routes. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx, NH3, and Br. See also BROMIDES.
 Hazard Codes : Xi
Risk Statements : 36/37/38
R36/37/38 : Irritating to eyes, respiratory system and skin
Safety Statements : 26-36
S26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:  Wear suitable protective clothing.  
WGK Germany : 3