Products Categories
CAS No.: | 5460-31-1 |
---|---|
Name: | 2-Methyl-3-nitrophenol |
Article Data: | 12 |
Molecular Structure: | |
Formula: | C7H7NO3 |
Molecular Weight: | 153.137 |
Synonyms: | 2-methyl-3-nitro-phenol;phenol, 2-methyl-3-nitro-;3-Nitro-o-cresol;2-hydroxy-6-nitro toluene;6-Hydroxy-2-nitrotoluene; |
EINECS: | 226-739-0 |
Density: | 1.32 g/cm3 |
Melting Point: | 146-148 °C(lit.) |
Boiling Point: | 269.5 °C at 760 mmHg |
Flash Point: | 121.8 °C |
Appearance: | yellow to brown crystalline powder |
Hazard Symbols: | Xn,Xi |
Risk Codes: | 20/21/22-36/37/38 |
Safety: | 26-36/37/39 |
Transport Information: | UN 2446 6.1/PG 3 |
PSA: | 66.05000 |
LogP: | 2.13200 |
Conditions | Yield |
---|---|
With sulfuric acid; sodium nitrite In water | 83% |
Stage #1: 3-nitro-o-tolylamine With sulfuric acid; sodium nitrite In water at 0℃; Stage #2: With sulfuric acid; water Reflux; | 67% |
Diazotization; | |
With sulfuric acid; water; sodium nitrite Diazotization; | |
(i) NaNO2, aq. H2SO4, (ii) CuSO4; Multistep reaction; |
Conditions | Yield |
---|---|
With boron tribromide In dichloromethane at -5 - 20℃; for 12h; Inert atmosphere; | 69.7% |
ortho-cresol
A
3-nitro-o-cresol
B
2,2'-dimethyl-4,4'-biphenol
C
4,4'-dihydroxy-3,3'-dimethyl-5,5'-dinitrobiphenyl
D
4,4'-dihydroxy-3,3'-dimethyl-6-nitrobiphenyl
Conditions | Yield |
---|---|
With ammonium cerium(IV) nitrate In acetic acid for 16h; Ambient temperature; | A 20% B 20% C 35% D 20% |
With ammonium cerium(IV) nitrate In acetic acid for 16h; Ambient temperature; | A 20% B 20% C 35% D 20% |
With ammonium cerium(IV) nitrate In water for 1h; Ambient temperature; | A 16% B 12% C 28% D 16% |
With ammonium cerium(IV) nitrate Ambient temperature; water or acetic acid; | A 16% B 12% C 28% D 16% |
With ammonium cerium(IV) nitrate; acetic acid Ambient temperature; water or acetic acid; | A 16% B 12% C 28% D 16% |
2-methoxy-3-methyl-4-nitro-aniline
A
3-nitro-o-cresol
B
6-methoxy-2-nitrotoluene
Conditions | Yield |
---|---|
With sulfuric acid; sodium nitrite Diazotization; | |
beim Diazotieren und Verkochen der schwefelsauren Diazoniumloesung; |
Conditions | Yield |
---|---|
Verkochen.Diazotization; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: alcohol; hydrogen sulfide; ammoniacal 2: concentrated sulfuric acid; water; sodium nitrite / Diazotization View Scheme |
2-methoxy-3-methylaniline
3-nitro-o-cresol
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 2: nitric acid 3: concentrated hydrochloric acid 4: beim Diazotieren und Verkochen der schwefelsauren Diazoniumloesung View Scheme |
acetic acid-(2-methoxy-3-methyl-anilide)
3-nitro-o-cresol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: nitric acid 2: concentrated hydrochloric acid 3: beim Diazotieren und Verkochen der schwefelsauren Diazoniumloesung View Scheme |
acetic acid-(2-methoxy-3-methyl-4-nitro-anilide)
3-nitro-o-cresol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: concentrated hydrochloric acid 2: beim Diazotieren und Verkochen der schwefelsauren Diazoniumloesung View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: [(2-di-cyclohexylphosphino-3,6-dimethoxy-2’,4’,6’-triisopropyl-1,1‘-biphenyl)-2-(2‘-amino-1,1’-biphenyl)]palladium(II) methanesulfonate; caesium carbonate / toluene / 16 h / 70 °C / Inert atmosphere 2: boron tribromide / dichloromethane / 12 h / -5 - 20 °C / Inert atmosphere View Scheme |
What can I do for you?
Get Best Price
Molecular Structure:
IUPAC Name:2-methyl-3-nitrophenol
Molecular Formula:C7H7NO3
Molecular Weight:153.135380 g/mol
Appearance:yellow to orange to brown crystalline powder
Melting Point:146-148 °C
Density:1.32 g/cm3
Flash Point:121.8 °C
Enthalpy of Vaporization:52.8 kJ/mol
Boiling Point:269.5 °C at 760 mmHg
Vapour Pressure:0.00437 mmHg at 25 °C
Water Solubility:2235 mg/L at 25 °C
BRN:1946057
EINECS:226-739-0
Synonyms of 2-Methyl-3-nitrophenol (CAS NO.5460-31-1): EINECS 226-739-0 ; 3-Nitro-o-cresol
Categories: Multisubstituted Benzene ; Alcohols and Derivatives ; Aromatic Phenols ; Phenol&Thiophenol&Mercaptan
2-Methyl-3-nitrophenol (CAS NO.5460-31-1) is used in organic synthesis, medicine and dye synthesis.
Safety Information of 2-Methyl-3-nitrophenol (CAS NO.5460-31-1):
Hazard Codes:Xn,Xi
Risk Statements:20/21/22-36/37/38
20/21/22:Harmful by inhalation, in contact with skin and if swallowed
36/37/38:Irritating to eyes, respiratory system and skin
Safety Statements:26-36/37-36/37/39-36
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37:Wear suitable protective clothing and gloves
36/37/39:Wear suitable protective clothing, gloves and eye/face protection
36:Wear suitable protective clothing
RIDADR:UN 2446 6.1/PG 3
WGK Germany:3
F:10
Hazard Note:Harmful
HazardClass:6.1
PackingGroup:III
First Aid Measures of 2-Methyl-3-nitrophenol (CAS NO.5460-31-1):
Eyes:Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:Get medical aid. Wash mouth out with water.
Inhalation:Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Storage of 2-Methyl-3-nitrophenol (CAS NO.5460-31-1):
Store in a cool, dry place. Store in a tightly closed container.