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553-69-5

Basic Information
CAS No.: 553-69-5
Name: PHENYRAMIDOL
Article Data: 11
Molecular Structure:
Molecular Structure of 553-69-5 (PHENYRAMIDOL)
Formula: C13H14 N2 O
Molecular Weight: 214.267
Synonyms: Benzylalcohol, a-[(2-pyridylamino)methyl]-(6CI,7CI,8CI); (?à)-Phenyramidol;2-(b-Hydroxyphenethylamino)pyridine;Cabral; Evasprin; Fenyramidol; NSC 23634; Phenyramidol; a-(2-Pyridylaminomethyl)benzylalcohol
Density: 1.206g/cm3
Melting Point: 82-85°
Boiling Point: 383.2°Cat760mmHg
Flash Point: 185.5°C
Safety: Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx.
PSA: 45.15000
LogP: 2.30010
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Chemistry

IUPAC Name: 1-Phenyl-2-(pyridin-2-ylamino)ethanol
Synonyms of Phenylramidol (CAS NO.553-69-5) : (±)-Phenyramidol ; 1-Phenyl-2-(2-pyridinylamino)ethanol ; 1-Phenyl-2-(pyridin-2-ylamino)ethanol ; 2-(b-Hydroxyphenethylamino)pyridine ; Fenyripo
CAS NO: 553-69-5
Molecular Formula:C13H14N2O
Molecular Weight :214.2631
Molecular Structure :
EINECS: 209-044-7
Index of Refraction:1.647
Surface Tension: 56.8 dyne/cm
Density: 1.206 g/cm3
Flash Point: 185.5 °C
Enthalpy of Vaporization: 66.63 kJ/mol
Boiling Point: 383.2 °C at 760 mmHg
Vapour Pressure: 1.48E-06 mmHg at 25°C

Uses

 Phenylramidol (CAS NO.553-69-5) is used as  intermediate in organic synthesis.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 355mg/kg (355mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ANTIPSYCHOTIC

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 141, Pg. 83, 1963.
mouse LD50 intravenous 124mg/kg (124mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Archives Internationales de Pharmacodynamie et de Therapie. Vol. 141, Pg. 83, 1963.
mouse LD50 oral 1850mg/kg (1850mg/kg)   Bollettino Chimico Farmaceutico. Vol. 103, Pg. 245, 1964.
mouse LD50 subcutaneous 405mg/kg (405mg/kg) BEHAVIORAL: ANTICONVULSANT Acta Pharmacologica et Toxicologica. Vol. 19, Pg. 247, 1962.
rat LD50 oral 756mg/kg (756mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ANTIPSYCHOTIC

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 130, Pg. 280, 1961.

Safety Profile

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. When Phenylramidol (CAS NO.553-69-5) is heated to decomposition ,it emits toxic fumes of NOx.