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| CAS No.: | 57-42-1 |
|---|---|
| Name: | MEPERIDINE |
| Article Data: | 20 |
| Molecular Structure: | |
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| Formula: | C15H21 N O2 |
| Molecular Weight: | 247.337 |
| Synonyms: | Isonipecoticacid, 1-methyl-4-phenyl-, ethyl ester (8CI);1-Methyl-4-phenyl-4-piperidinecarboxylic acid ethyl ester;4-Carbethoxy-1-methyl-4-phenylpiperidine; Demerol; Ethyl1-methyl-4-phenylisonipecotate; Ethyl1-methyl-4-phenylpiperidine-4-carboxylate; Isonipecaine; Meperidine; Meperidol;Pethanol; Pethidin; Pethidine; Pethidineter; Petidina; Renaudin |
| EINECS: | 200-329-1 |
| Density: | 1.055g/cm3 |
| Melting Point: | 270°C |
| Boiling Point: | 328.9°Cat760mmHg |
| Flash Point: | 111.6°C |
| Solubility: | 6.55g/L(25 oC) |
| Hazard Symbols: | F,T |
| Risk Codes: | 11-23/24/25-39/23/24/25 |
| Safety: | A human poison by an unspecified route. Poison experimentally by ingestion, subcutaneous, intravenous, intradermal, parenteral, and intraperitoneal routes. Human systemic effects by unspecified route: changes in sleep patterns and muscle weakness. Human reproductive effects by intramuscular route: effects on measurements and viability of newborn. A pharmaceutical painkiller. When heated to decomposition it emits toxic fumes of NOx. See also ESTERS. |
| PSA: | 29.54000 |
| LogP: | 2.15100 |
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This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.
Chemistry
Chemical Name: Meperidine
IUPAC NAME: Ethyl 1-methyl-4-phenylpiperidine-4-carboxylate
CAS No.: 57-42-1
EINECS: 200-329-1
Molecular Formula: C15H21NO2
Molecular Weight: 247.33 g/mol
Density: 1.055 g/cm3
Flash Point: 111.6 °C
Boiling Point: 328.9 °C at 760 mmHg
Storage temp.: -20°C
Following is the structure of Demarol (57-42-1):
Product Categories about Demarol (57-42-1) are Controlled Drug StandardsAlphabetic ; M ; MEA - MES ; Stable Isotopes
The chemical synonymous of Demarol (57-42-1) are Meperidine ; 1-Methyl-4-phenyl-4-piperidinecarboxylic acid ethyl ester ; 1-Methyl-4-phenyl-4-piperidinecarboxylicaciethylester ; 1-Methyl-4-phenylisonipecotic acid, ethyl ester ; 1-Methyl-4-phenylisonipecoticacid,ethylester ; 1-Methyl-4-phenylisonipecoticacidethylester ; 1-Methyl-4-phenyl-isonipecoticaciethylester
Toxicity Data With Reference
| 1. | unr-man LDLo:15 mg/kg | 85DCAI Poisoning; Toxicology, Symptoms, Treatments. 2 (1970),73. | ||
| 2. | unr-man TDLo:57 mg/kg:CNS | NEJMAG New England Journal of Medicine. 312 (1985),509. | ||
| 3. | orl-rat LD50:162 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 180 (1969),155. | ||
| 4. | ipr-rat LD50:87 mg/kg | JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. 47 (1958),323. | ||
| 5. | scu-rat LD50:113 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 24 (1974),600. | ||
| 6. | ivn-rat LD50:29 mg/kg | DDREDK Drug Development Research. 1 (1981),83. | ||
| 7. | idu-rat LD50:90 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 180 (1969),155. | ||
| 8. | orl-mus LD50:200 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 135 (1962),376. | ||
| 9. | ipr-mus LD50:150 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 135 (1962),376. | ||
| 10. | par-mus LD50:178 mg/kg | JMCMAR Journal of Medicinal Chemistry |
Safety Profile
A human poison by an unspecified route. Poison experimentally by ingestion, subcutaneous, intravenous, intradermal, parenteral, and intraperitoneal routes. Human systemic effects by unspecified route: changes in sleep patterns and muscle weakness. Human reproductive effects by intramuscular route: effects on measurements and viability of newborn. A pharmaceutical painkiller. When heated to decomposition it emits toxic fumes of NOx. See also ESTERS.
Hazard Codes:
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F: Flammable .gif){kind=small}
Risk Statements about Demarol (57-42-1):
R11 Highly flammable.
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements about Demarol (57-42-1):
S7 Keep container tightly closed.
S16 Keep away from sources of ignition.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S24/25: Avoid contact with skin and eyes.