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CAS No.: | 57432-61-8 |
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Name: | Methylergonovine maleate salt |
Molecular Structure: | |
Formula: | C20H25N3O2.C4H4O4 |
Molecular Weight: | 455.511 |
Synonyms: | Methergine;Ergoline-8-carboxamide,9,10-didehydro-N- [(1S)-1-(hydroxymethyl)propyl]-6-methyl-,(8a)-,(2Z)-2-butenedioate (1:1) (salt);Methylergometrine maleate (JP14);Methylergometrine maleate;Methylergonovine maleate;Methylergonovine maleate (USP);Methergine (TN);Erezin;METHYL ERGOMETRINE MALEATE;METHYLERGONOVINE MALEATE;METHYLERGOBASINE MALEATE;USAF UCTL-8;METHEGRIN;MALEIC ACID, METHYL ERGONOVINE; |
EINECS: | 260-734-4 |
Density: | g/cm3 |
Melting Point: | 1720C (dec) |
Boiling Point: | 638.4°Cat760mmHg |
Flash Point: | 339.9°C |
Hazard Symbols: | |
Risk Codes: | R23/24/25;R62 |
Safety: | Poison by ingestion, intravenous, and intraperitoneal routes. Human teratogenic and reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. |
Transport Information: | UN 1544 |
PSA: | 142.96000 |
LogP: | 1.96530 |
Product Name: Methylergonovine maleate (CAS NO.57432-61-8)
Molecular Formula: C24H29N3O6
Molecular Weight: 455.5g/mol
Mol File: 57432-61-8.mol
Einecs: 260-734-4
Appearance: Crystalline Solid
Boiling point: 638.4 °C at 760 mmHg
Flash Point: 339.9 °C
Water Solubility: H2O: 25 mg/mL
Enthalpy of Vaporization: 99.09 kJ/mol
Vapour Pressure: 3.6E-17 mmHg at 25°C
XLogP3-AA:
H-Bond Donor: 5
H-Bond Acceptor: 7
Product Categories: Intermediates and Fine Chemicals; Metabolites and Impurities; Pharmaceuticals
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 6mg/kg (6mg/kg) | National Technical Information Service. Vol. AD277-689, | |
mouse | LD50 | intravenous | 85mg/kg (85mg/kg) | Drugs in Japan Vol. 6, Pg. 828, 1982. | |
mouse | LD50 | oral | 187mg/kg (187mg/kg) | Drugs in Japan Vol. 6, Pg. 828, 1982. | |
rabbit | LD50 | intravenous | 2600ug/kg (2.6mg/kg) | Drugs in Japan Vol. 6, Pg. 828, 1982. | |
rat | LD50 | intravenous | 23mg/kg (23mg/kg) | Drugs in Japan Vol. 6, Pg. 828, 1982. | |
rat | LD50 | oral | 93mg/kg (93mg/kg) | Drugs in Japan Vol. 6, Pg. 828, 1982. | |
women | TDLo | oral | 36ug/kg/3D-I (0.036mg/kg) | CARDIAC: CARDIOMYOPATHY INCLUDING INFARCTION CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE | American Journal of Emergency Medicine. Vol. 16, Pg. 502, 1998. |
Poison by ingestion, intravenous, and intraperitoneal routes. Human teratogenic and reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Safety Information of Methylergonovine maleate (CAS NO.57432-61-8):
Hazard Codes: T
Risk Statements: 23/24/25-62
23: Toxic by inhalation
24: Toxic in contact with skin
25: Toxic if swallowed
62: Possible risk of impaired fertility
Safety Statements: 36/37/39-45
36: Wear suitable protective clothing
37: Wear suitable gloves
39: Wear eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
Methylergonovine maleate ,its CAS NO. is 57432-61-8,the synonyms is Erezingen ; Maleicacid,methylergonovine ; Methergine ; Methylergobasinemaleate ; Methyl-ergonovinmaleate(1:1) ; Methylergometrine maleate ; Methylergonovine maleate salt .