CAS No.57982-78-2,BUDIPINE Suppliers

Products Categories

Pharmaceutical (24)
Organic Chemicals (5)
Others (3)
Agrochemicals (1)
Reagent (1)
Materials (1)

Basic Information

Molecular Structure:
CAS No.:	57982-78-2
Name:	BUDIPINE
Article Data:	1

Formula:	C21H27 N
Molecular Weight:	293.452
Synonyms:	1-tert-Butyl-4,4-diphenylpiperidine;Budipine
Density:	1.009g/cm³
Melting Point:	108.5°C
Boiling Point:	387.6°Cat760mmHg
Flash Point:	168.7°C
Safety:	Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x.
PSA:	3.24000
LogP:	4.80490

Synthetic route

: 1465-76-5
1-tert-butyl-piperidin-4-one

: 71-43-2
benzene

: 57982-78-2
budipine

Conditions

Conditions	Yield
With aluminium trichloride at 60℃; for 2h; Yield given;

: 81831-81-4
(1-tert-butyl-4-hydroxy-4-phenyl-piperidin-3-yl)-phenyl-methanone

: 71-43-2
benzene

A: 57982-78-2
budipine

B: 1,4-Bis<1-tert-butyl-4-phenyl-piperidyl-(4)>-benzol

Conditions

Conditions	Yield
With aluminium trichloride 1.) 45 deg C, 30 min, 2.) 50-55 deg C, 1 h; Yield given;

...Expand

Raw Materials

71-43-2

1465-76-5

Total:35 Page 1 of 1 1

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 57982-78-2

Chemistry

Chemistry informtion about Budipine (CAS NO.57982-78-2) is:
IUPAC Name: 1-Tert-Butyl-4,4-Diphenylpiperidine
Synonyms: Budipine ; 1-(1,1-Dimethylethyl)-4,4-Diphenyl-Piperidin ; 1-(1,1-Dimethylethyl)-4,4-Diphenylpiperidine ; Budipin ; 1-Tert-Butyl-4,4-Diphenyl-Piperidine ; Budipine(Forr&Donly) ; 4,4-Diphenyl-1-Tert-Butyl-Piperidine
MF: C₂₁H₂₇N
MW: 293.45
EINECS: 261-062-4
Density: 1.009 g/cm³
Flash Point: 168.7 °C
Boiling Point: 387.6 °C at 760 mmHg
Vapour Pressure: 3.25E-06 mmHg at 25°C
Enthalpy of Vaporization: 63.67 kJ/mol
Following is the molecular structure of Budipine (CAS NO.57982-78-2) is:

Uses

Budipine (CAS NO.57982-78-2) is believed to be a NMDA receptor antagonist, and to promote the synthesis of dopamine. Because it provides additional benefits relative to existing treatments, it probably does not precisely mimic the mechanism of an existing known treatment.

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intravenous	33mg/kg (33mg/kg)	Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 85, 1982.
mouse	LD50	oral	120mg/kg (120mg/kg)	Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 85, 1982.
rat	LD50	intravenous	28mg/kg (28mg/kg)	Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 85, 1982.
rat	LD50	oral	165mg/kg (165mg/kg)	Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 85, 1982.

Safety Profile

Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x.

Specification

Budipine (CAS NO.57982-78-2) is a dopaminergic agent. Its mechanism is not well characterized.