Products Categories
CAS No.: | 6231-18-1 |
---|---|
Name: | 2,6-Dimethoxypyridine |
Article Data: | 8 |
Molecular Structure: | |
Formula: | C7H9NO2 |
Molecular Weight: | 139.154 |
Synonyms: | 2,6-Dimethoxypyridin; |
EINECS: | 228-334-4 |
Density: | 1.064 g/cm3 |
Boiling Point: | 178.7 °C at 760 mmHg |
Flash Point: | 61.7 °C |
Appearance: | clear colorless to light yellow liquid |
Hazard Symbols: | Xn, Xi |
Risk Codes: | 22-37/38-41-36/37/38-20/21/22 |
Safety: | 26-39-36/37/39-36 |
Transport Information: | UN 1993 |
PSA: | 31.35000 |
LogP: | 1.09880 |
Conditions | Yield |
---|---|
With sodium hydroxide | 94% |
With 5-(di(adamantan-1-yl)phosphino)-1′,3′,5′-triphenyl-1′H-1,4′-bipyrazole; palladium diacetate; caesium carbonate In toluene at 80℃; for 24h; | 77% |
With 5-(di-tert-butylphosphino)-1′, 3′, 5′-triphenyl-1′H-[1,4′]bipyrazole; tris-(dibenzylideneacetone)dipalladium(0); potassium hydroxide at 0.1℃; for 3h; Inert atmosphere; |
Conditions | Yield |
---|---|
With sodium hydroxide for 8h; Reflux; | 94% |
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 80℃; | 65% |
Conditions | Yield |
---|---|
With sodium methylate In N,N-dimethyl-formamide at 80℃; for 2h; | 65% |
2,6-dichloropyridine
sodium methylate
A
6-chloro-2-methoxypyridine
B
2,6-dimethoxypyridine
Conditions | Yield |
---|---|
In methanol for 25h; Heating; | A 80 % Spectr. B 20 % Spectr. |
Conditions | Yield |
---|---|
at 40℃; under 4500450 Torr; for 24h; Hilbert-Johnson reaction; | 100% |
at 80℃; for 24h; | 72% |
2,6-dimethoxypyridine
3-iodo-2,6-dimethoxypyridine
Conditions | Yield |
---|---|
Stage #1: 2,6-dimethoxypyridine With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; zinc dichloro(N,N,N′,N′-tetramethylethylenediamine) In tetrahydrofuran; hexane at 20℃; for 2h; Inert atmosphere; Stage #2: With iodine In tetrahydrofuran; hexane at 20℃; Concentration; Time; Inert atmosphere; regioselective reaction; | 98% |
With iodine; silver(I) acetate In acetonitrile at 23℃; for 0.5h; | 80% |
With iodine; sodium hydrogencarbonate at 20℃; | 41% |
With dichloro(N,N,N’,N‘-tetramethylethylenediamine)zinc; 2,2,6,6-tetramethylpiperidinyl-lithium In tetrahydrofuran at 20℃; for 2h; |
2,6-dimethoxypyridine
3-bromo-2,6-dimethoxypyridine
Conditions | Yield |
---|---|
With N-Bromosuccinimide In acetonitrile at 80℃; for 18h; | 97% |
With N-Bromosuccinimide In acetonitrile for 10h; Reflux; | 89% |
With N-Bromosuccinimide In acetonitrile for 10h; Heating; | 85% |
Conditions | Yield |
---|---|
With (dppf)Ni(o-tol)Cl; caesium carbonate In neat (no solvent) at 130℃; for 16h; Inert atmosphere; Sealed tube; | 96% |
Conditions | Yield |
---|---|
With C25H36O2P2Ru In tetrahydrofuran at 120℃; for 12h; Inert atmosphere; Sealed tube; | 96% |
What can I do for you?
Get Best Price
Hazard Codes Xn,Xi
Risk Statements 22-37/38-41-36/37/38-20/21/22
Safety Statements 26-39-36/37/39-36
RIDADR 1993
WGK Germany 3
HazardClass 3.2
PackingGroup III